Cohort four, final phase 1a cohort18 Oct 2022 09:35
I know it's all made up, but AVA6k, the drug that received orphan drug designation from the FDA enters is seventh week dosing patients at 200mg (equivalent of 135mg of dox, which would do serious harm if freely circulating in the body).
Probably a few more weeks to run, this positive progress reflects the safety profile and tolerability in patients (of this made up drug).