RE: Biopsies.20 Oct 2022 13:14
We won't know, until we know, but AS has been pretty vocal about him being confident that we will have biopsies.
That is a secondary objective in this phase anyway but obviously great to have.
Primary objectives:
-Evaluating safety and tolerability
-determine MTD and/or recommended phase 2 dose
Secondary objectives:
- characterise the pharmacokinetics in plasma, urine and tumour of AVA6000, of the pre|CISION leaving group, and of active metabolites (Doxorubicin and doxorubicinol) when given as monotherapy, after a single dose and after multiple dosing
- to evaluate the initial anti-tumour activity
You'd think after this long 450 days odd then at least one of those secondary objectives will be achievable