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Thanks for the further info bignose.does seem a tad odd to be saying basically we have no say in the manufacturing process etc. one might have expected some degree of mutuality in the rights and obligations under the licence agreement which would give regent some say over things.i suppose when you are in such a weak position as regent is, having enforceable rights on paper may simply be an academic point in practice (no alternative).sorry im just chuntering i know.

Morning bignose. yes i imagine royalty finance is like that.you take a percentage of ultimate royalties etc,which could impact future earnings dramatically. all speculation of course and i suppose the other side of the coin is that mellon has considerable resources at his disposal,so not in the same desperate situation which some companies are in when they resort to damaging finance options. anyway time will tell.on the clinical holds point,i agree that a potential finance provider would certainly want the reassurance of a formal SPA before proceeding.i probably didn't express myself clearly,as i was just wondering if the no holds statement indicated any real progress with the fda and was not suggesting regent might go ahead without one. lets hope for NDA submission news without further delay.

Sorry, lanstead, not lansdown.memory not what it was.

Cont. as to royalty financing,my ears did prick up on hearing this. whilst i'm familiar with a lot of last resort financing (e.g. convertible loan notes of the death spiral variety, such as specialised in by companies like lansdown), im not familiar with royalty financing as such. i assume,on the principle that no one does anything for free, this would come at a very considerable cost in terms of regent's potential profitability, even if it is not in strict terms,dilutive.i f anyone is familiar with this type of finance and has experienced it in practice i would be interested to hear their thoughts. of course,anything (within reason) which enables regent to carry on and leaves at least a little on the table for its PIs is better that going bust, but i do have concerns as to the road regent may have to go down in that regard.

well that's more than enough from me.gla

I mentioned earlier the there were 2 or 3 particular points in the response which caught my attention.first it was good to see the identity of the manufacturer.second,the figures given re manufacturing capability seem to be of a different order from what we have been told in the past.i sense you feel likewise and are somewhat sceptical of this,a sensible approach bearing in mind how often Regent 's statements have had only a passing acquaintance with accuracy.

the main points however, were their statement about no clinical holds and the reference to royalty financing. does the reference to "no clinical holds"mean that they could in principle (certainly not in practice proceed with a trial ,but without the benefit of a formal SPA?.my understanding,which may well be inaccurate, is that an SPA is not essential for a trial to take place,but the risk is much greater as there would have been no formal agreement with the fda on the criteria and format etc of such trial. having a formal spa in place is, equally, no guarantee of the trial drug being approved, even if the results meet the endpoints specified in the protocol, as the fda will still want to assess the trial results on the basis of their normal criteria. so,having no clinical holds does not mean we have any substantive form of go-ahead, but it does perhaps indicate that the discussions so far with the FDA have achieved some degree of tangible progress. just my musings of course. tbc

Its!

Articles are two a penny.https://finance.yahoo.com/news/heres-why-were-not-concerned-064340814.html i haven't read the full mail article,but from the extract quoted,it's stance appears very much at odds withe the general interpretation of the results.

Morning bignose.no i hadn't seen it,so thanks very much for that. interesting that mellon through galloway is prepared to extend a further loan.small beer to him of course,but presumably indicates he can still see some light t the end of the tunnel.i agree it's prudent to be sceptical about any rerate in view of the history here, but i suppose it is possible. q1 is now over and no news on submission,but as you say could be any time.

kudos to you again for pursuing a direct approach to the board and eliciting the response posted yesterday. tbh, i had completely given up on a direct approach in light of the wall of silence which seemed to prevail.very glad you have proved me wrong.

there were 2 or 3 nuggets of information in their reply,which i will comment on later, hopefully.

Completely agree,weareallguessing. i also topped up this afternoon when the s/p appeared to have stabilised.when you consider the likely news flow over the next 12 months or so,it is very hard to imagine the s/p staying at this low level for long.aimo.

Bignose,thanks very much for the detailed post.much appreciated. need to look at it in detail later.

Afternoon bignose.agree with that.i haven't bothered to calculate the value of a 10k trade but it is less than £1000 think.these anomalous rises and falls on derisory volume don't mean anything imo.still t least it was a rise.

I ss we have a trading statement on the 12th, presumably ahead of the agm.

Another tweet.presumably this is,or is part of,the new launch referred to in the results.nothing exciting,but just for info. https://twitter.com/Deep_Longevity/status/1775968994643562996?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Etweet

As I've commented before on the absence of any observable activity from dli for a considerable time,i should perhaps point out a tweet now,which is the first i think for 8/9 months. nothing of significance in itself, but at least a small sign of life

https://twitter.com/Deep_Longevity/status/1775596244968092123?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Etweet

Last year notice of results on 6th april and results on 18th April. so expect to hear probably by end of this week. as to the wider market, i have holdings in a number of different ares and virtually all of them have been market down fairly aggressively today. thg is not the worst.

Just a reminder that the delisting meeting is set for 4th april. will be interesting to see if aim listing stimulates any retail interest.

Morning bignose.no problem.optimism is probably going it a bit.just relief that we did not get the bad news i was more than half expecting. i do of course,entirely agree with your post (and yours dougie,morning).the level of failure to advise as to promulgated developments is what you would expect from the most tin pot of aim companies and this is,despite its pitiful market cap,a main market company.anyway, question is will we get an announcement of china submission in next couple of weeks or silence and more delay?place your bets.

i hope mrs wylie,who is after all an innocent bystander in this sorry story, does not take offence at my poor attempt at humour,or else i shall also be exiled to the realm of those to whom no communication may be extended!

bothwell good morning to you also. i suspect we are,sadly, very far from mellon's thoughts now.

I am assured that Mie Wylie is a charming lady and a highly competent CSO to boot!

Interesting post, canary.certainly puts the decision to retain the right to market in non iceland territories in an interesting light.( here could be many reasons for this, but the aim to market in say the us is clearly one strong possibility.

It is difficult to know exactly what is meant by 10 launches,as 'alunch seems to be a slightly fluid concept.we did have the option exercised by N8 for 14 additional south american countries (a not insignificant thing in itself), but i assume none of these were included in the scope of the reference to 10 new, as they were the result of the option exercise. however, i'm personally not too bothered by whether or not anything is announced, as the important news re launches/marketing is principally the US and china. also im not getting too excited by what figures are given in the results as i still think it is very early days. im more inclined to take a slightly longer term view from the perspective of the current and potential totality of the aggregated markets. there is a map on fum's website which give an indication of the reach. mightily impressive imo. i accept that there will be other views of course.