RE: Kissei28 Oct 2019 22:45
Super interesting read...the figures quoted make more sense now - if NFX have cracked Tranislast then having rights to that platform will be hugely valuable for Kissei...
“It has been reported that tranilast has the ability to induce or enhance neurogenesis and, therefore, could be used as an agent to treat neuronal conditions such as cerebral ischemia, glaucoma, multiple sclerosis, amyotrophic lateral sclerosis, Alzheimer's disease, neurodegenerative trinucleotide repeat disorders, neurodegenerative lyosomal storage diseases, spinal cord injury and trauma, dementia, schizophrenia and peripheral neuropathy (A. Schneider. EP2030617).”
“Tranilast, as discussed above, is known to possess anti-allergic, anti-fibrotic, anti-inflammatory, anti-tumor, neurogenesis enhancing and angiogenesis inhibitory properties. The tranilast complexes and cocrystals of the invention may then be used, in the same way as tranilast, to treat diseases, disorders and conditions, such as those discussed above, that are associated with such properties. Accordingly, the invention relates to the method of treating such a disease, disorder, or condition comprising the step of administering to a patient in need thereof a therapeutically effective amount of a tranilast complex or cocrystal of the invention or of administering to a patient in need thereof a therapeutic composition containing a tranilast complex or cocrystal of the invention.”