Member Info for Sangijuelas1

Better tell Innova quick not to build that factory in Wales

Just filter it. It's one of the bots that has found a way to hack dormant LSE accounts to spread FUD.

Did you not get your unicorn Mrs K? I am told mine is held up at customs for the foreseeable

Nice to see Gokul from MSD Exploratory Science division also speaking here.
https://microbiome-summit.com/speaker/gokul-swaminathan/

He is the MSD lead for the vaccines collaboration. Interview posted with him on his LinkedIn.
https://www.linkedin.com/in/gokul-swaminathan-53409810

He shared the 4D post with Times Square photo from the Nasdaq listing

I think the media are part of the whole murky mess.

Look at the screenshot of this Kim Thonger tweet (the Innova dealmaker) where he is contacting Nick Robinson and shows another message from Sky's Tom Parmenter who he thanks for helping him connect with the Department of Health regarding supplying ventilators

https://mobile.twitter.com/JuneSim63/status/1326154712010412036

Kim has now made his Twitter private

Thanks for explaining that Monkshood. So do you reckon there's no reason why the Innova tests would be any less effective than previously for detecting Delta?

It's Innova that say that amino acid changes that there MAB binds to could render the test less effective. Another article said that these are different to the main Delta spike mutation

Worth revisiting this Guardian article
https://www.google.com/amp/s/amp.theguardian.com/world/2021/jan/28/how-uk-spent-800m-on-controversial-covid-tests-for-dominic-cummings-scheme

Deaths in nursing home linked to Innova false negatives
https://www.theguardian.com/world/2021/jan/22/care-homes-face-devastating-results-of-losing-englands-covid-jab-lottery

The screenshot of an email from David Evans to Andrew Marr at the bottom of this thread is interesting
https://mobile.twitter.com/sensetalka/status/1409867483981488130

Yeah I thought I corrected myself about the spike.

This article mentions the N changes, which the Innova document says might make the test less effective

"Other mutations in Delta could help it thwart immunity. Some alter the spike's N-terminal domain (NTD), which protrudes from the protein's surface. A recent Cell paper identified one spot in the NTD as a “supersite,” unfailingly targeted by “ultra-potent” neutralizing antibodies from recovered patients. Delta's unique mutations delete the amino acids at positions 156 and 157 in the supersite and changes the 158th amino acid from arginine to glycine; the latter eliminates a direct contact point for antibody binding, says David Ostrov, a structural biologist at the University of Florida. “We think the 157/158 mutation is one of the hallmark mutations in Delta that has given it this more immune-evasion phenotype,” concurs Trevor Bedford, a computational biologist at the Fred Hutchinson Cancer Research Center."
https://science.sciencemag.org/content/372/6549/1375?rss=1

This Scottish MP was cut off in the midday of his question to Lopez yesterday about Innova, mentions something about the Innova tests being reassessed at PD

https://mobile.twitter.com/JNHanvey/status/1409852749928411139

They say more will be revealed tomorrow

https://www.theguardian.com/politics/2021/jun/30/bids-from-politically-connected-firms-for-covid-test-contracts-designated-fast-track-email-suggests

I don't think that would be very helpful

You are on here and Angle AgentB. Good job

Exactly, AS used to talk about the Ablynx buyout by Sanofi at £3bn but I think they have set their sites higher now.

Anyone still not convinced really needs to look again at the Trinity Delta note

They might not be detecting the amino acid changes in Delta as per my post below

Good overview of KRAS inhibitors from MD Anderson Cancer Centre. Written by guy overseeing 4D Pharma's cancer trials.

https://www.mdanderson.org/cancerwise/targeting-the-kras-mutation-for-more-effective-cancer-treatment.h00-159458478.html#:~:text=KRAS%20mutations%20are%20present%20in,90%25%20of%20pancreatic%20cancer%20cases.

Darpin from Molecular Partners was mentioned in the Trinity Delta note

Pfizer has been approved for 12-15 year olds in the UK.