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Good afternoon Rebster408.
I did sell just under a million at 9.2 p old money.
Not sure where MAJWandCo, Puma or Robin Hood of AIM are these days, very quiet.
Still along way to climb on this one just to get back to normality or around 70p per share to bring market cap to as it was pre Right Fleecerd equity swap.
That will be gone very very soon within next week or so, shares will become far less a binding then we can expect steady rise up until the good news.
1 Riverfory bombed out
2 clinical trial safety data being satisfactory and progression to either phase1b or 2a.
3 possibly progress with details of on licensee for 737 along with their progress and intent.
Just dediating a tad here but l see a similarity between Mark Wheelet CLO of Riverfort and MAJWandCo as well as James Rooke and Puma.
Maybe just coincidence but interesting posts on LinkedIn thst reflect certain content of posts they put here. Nothing like a good game of golf to spread the word on the street haha.
Needs investigating as far as l am concerned.
Onwards and upwards and with 8 months if constant decline in the SP due to Rivetfort finance it is now time for share price reversal and we are still a very long way from where we should be.
You can have a good laugh over at the ADVN chatboatd at the absolute bile that they post.it is about time that two of them were put back in their specimen bottles in the lab.
How can you claim have achieved nothing in 20 years and at the same time claim to have sold at the spike in 2021.
Why on Earth don't the come on here and try and achieve reasoned debate?
Banned from here for the same behaviour they now carry out over at ADVN
Regards to all
Interesting link below. One of the Indications in SDC1801 patent description is Alzheimers
https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/trc2.12445#:~:text=The%20use%20of%20baricitinib%20in,CNS%20and%20may%20suppress%20neuroinflammation.
Regards
Don't go mad Wiggly keep a degree of calmness.
You can go on the ADVN chat site.
You will get a completely different opinion from a couple of posters on their.
So you can at least see what they see as downsides and make your own conclusions as to what is and what is not a viable investment.
Feel free to ask here, as there are knowledgeable posters that have been here for a significant period of time.
Regards
May get a slight drop as 3 million additional shares issued to Riverfort finance. It may well be they have forward sold most of them.
Regards
There is absolutely no reason as to why the SP should not recover Wiggly.
I did say a few days ago that an individual here who had an average of 61p should be in profit by end of May,
I also put that in my 100% belief on the removal of finance contract the SP should have a clear runway up to 100p
Further along we await news of phase1a clinical trial.
Following this with sufficient funding we can go phase 1b or phase 2a.
Advantage of phase 2 trials is therapeutic doses can be established per indication ( that cannot happen in phase 1b). Disadvantages are increased cost due to the number of clinical trial volunteers we get. Typically 100 to 300. Before anybody pipes up about Sareum only using 25 patients , they need understand that at these low numbers it is nothing more than proof of concept. However, phase 2 can start in 2a and lead into phase2b without further phase application.
Plus side is on satisfactory progression it greatly increases the value of SDC1801 and hence bring greater value to its shareholders, which will take some doing after the virtual abortion of a finance deal which had wiped around 90% from an already down trodden price.
Choice is yours what you do and when you tend to exit. As l see it steady growth whilst terminating RF finance deal followed by satisfactory phase 1a safety data results.
In addition we do have SRA 737 formerly CCT245737 a checkpoint 1 kinase inhibitor which was on licensed to a non named private company in the US.
That is about as much as l can say.
As for advice your two biggest enemies will be fear and greed. Fear of missing out that is.
Don't forget to take profit, when to take out is just as important if not more so than when to put in.
Regards
Funnyguy you are an extremely erratic
You post:-
'RE: Interesting Parallels 17 Apr 2024 02:27
Considering the current SAR performance, you would be bonkers not to take a price of 200-300m. I have little confidence that the results will propel this into the billions, its track record has been woeful and every turn it has disappointed. However, its not unrealistic with a bit of market spin this could get to a pound in a short time. To me sar is now definitely a short term play.'
What results are we looking at here?
Data results on its own will not reach 200 to 300 million, l will agree.
Phase 2a leading to phase 2b very likely to exceed the 300 million.
In addition we have SDC1802 for oncology coming to the end of preclinical.
Would you care to put your expert opinion as to a value of here?
Early Jak inhibitors all have black NDA black box warnings to adverse side effects.
No early first generation Jak 1, 2 and 3 inhibitors do not have the dreaded black box warnings either irrespective of claimed selectivity over.
Along comes Deucravacitinib, an allosteric Tyk2 inhibitor that has very good acceptable safety profile. It has proved mediocre to good efficacy in Psoriasis. It failed to meet its end points in ulcerative colitus. Very little different to the placebo used!
Clearly an allosteric Tyk2 whilst being safe is overly selective and thus will.show very poor results in some Indications.
SDC1801 is Tyk2 Jak 1 inhibitor.
The Jak 1 has approx 4 to 5 fold selectivity over Jaks 2 and 3.
This will prove to have far greater success in areas in which Deucravacitinib have and will.flunk.
It is a very competitive field that we are involved in.
Tell me in your expert opinion how many Tyk2 Jak inhibitors have been approved for clinical.use and if not approved, the reasons for.
Whilst l.understand your concern for the Sareum performance it is in no way an indication of the future performance.
The SDC Co.pounds have value irrespective of the current SP.
RF have decimated the SP here, absolutely nothing to do with non existent failings in the Sareum pipeline.
Regards
Many will be aware of forward selling but an interesting link below.
https://www.sharesoc.org/blog/regulations-and-law/forward-selling-a-crime-against-shareholders/#:~:text=Forward%20selling%20occurs%20when%20a,prior%20to%20actually%20receiving%20them.
Good evening Mathsprof,
certainly would not surprise me either, to recieve further news of RF issuance of shares.
It would be in their interest to request as many as possible to dispose if in a short time.
Parasites!
Soon they will be long gone, l reckon by end of the month.
Good afternoon the BoD.
I am fairly certain that raising of funds to a certain degree can be obtained by members of the LSE chatboard. Have you ever considered this as an option.
300k should not present too much of a problem and would far less damaging than any funding raised via RF
Regards
Yes it was substantial Billy.
I emailed sareum at 12.31 pm on 13th of March.
'Good afternoon the BoD.
I am fairly certain that raising of funds to a certain degree can be obtained by members of the LSE chatboard. Have you ever considered this as an option.
300k should not present too much of a problem and would far less damaging than any funding raised via RF
Yours Sincerely
So well done to all that participated.
Regards
Mitzy, l for one never said we are going bust.
Indeed, l was accused of ramping, l should be banned by the LSE due to my ramping causing investors huge losses, l cannot put a sentence together properly, by taking part in the WRAP offer l am causing the dilution of my own shares l already hold.
Yet some of these posters that choose to insult now would be classed as rampers.
I will add that we owe a lot to the individuals who visited Pampisford (they know who they are)
In addition l believe it was fearg that posted here regarding raising funds amongst ourselves to finance Sareum. Billy Bunter contacted Sareum and am certain that also an individual contacted Sareum with regards to the raise, specifically of 300k. This 300k due to the clauses in the RF agreement was not available to us.
A couple of days later an RNS appeared with a WRAP offer limited to raising 300k, it was heavily oversubscribed achieving nigh 1.2 million pounds.
In my opinion RF were looking to acquisition Sareum, by the use of the death spiral, followed by more funding to take the company over.
RF are evolving from an invest company into an acquisition company. Look at their history!
With the raising of funds this has been thwarted.
I would not rule out here any connection between 2 posters that came aboard in August 23 and RF.
Dilution has been achieved close to 45%
Sareum 70 million market cap prior to RF loan shark funding.
Minimum market cap should be 70 million around 70p per share.
On top of this we need to add the further development of 1801 ie phase1 a trial data results and interpretation thereof. The raising of further funding.
RF will be blown out of the water soon with respect to Sareum. Companies interested in on licensing or partnerships do wish to become involved with companies involved in this form of finance.
An RNS from Sareum stating the termination of the agreement with RF global finance should result in the current SP being propelled to the 70p per share mark.
Regards to all the LTH that never lose sight of the end goal.
On good news of 1801 funnyguy l reckon you will be in profit. Mid May to mid June.
737 development news will add a 4 or 5 million to market cap at least me thinks. Some will be taking profits on the way up but l would expect a steady rise increasing in momentum up till 1801 news with concrete RNS as to where we are heading and how.
Enough from me for a while, more than likely a very long while.
Regards to all.
Covid 19 vaccines ( around 8 in all) containing messenger RNA was never tested in vivo and was deemed safe.
However, there have been recent reports and complaints from some people that have suffered as a result.
We are looking at the long term effects that can happen in some people ( definitely not all) to people who are susceptible to, not having the ability of adequately reducing the synthetic messenger ribonucleic acid (mRNA) present in the vaccines.
'Intracellular accumulation of the nms-mRNA and the reverse transcribed cDNA molecules triggers intrinsic cytosolic RNA and DNA sensory pathways. Simultaneous activation of these pathways initiates a coordinated innate response against both types of non-self nucleic acids, prompting type-I interferon and pro-inflammatory cytokine production which if unregulated, leads to autoinflammatory and autoimmune conditions. Activated TEs increase the risk of insertional mutagenesis of the retrotranscribed vaccine mRNA, which can disrupt coding regions, enhance the risk of mutations in tumour suppressor genes, and lead to sustained DNA damage. '
Some people will be ok and some will not.
I don't think you will find much about this in mainstream media, indeed l doubt you will find much about the origin of Covid 19, a reverse engineered bat virus with a feron cleavage in which is inserted a segment, reportedly of HIV origin.
I tend to take anything the msm say with a pinch of salt.
Regards
Interesting read in the link below.
There are a couple if spelling mistakes in but on the whole, very good and informative.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959504/
Apologies if l have posted before.
Regards.
CB,
Most of the posts l put here are done on my mobile phone.
Are you not aware Cb, that after a full stop the next word starts with a capital letter?
As for seeing your own mistakes?
You may see the written mistakes, but you have a good deal more, that l dare say others will have pointed out.
Regards
Industry profits doubled over the course of the pandemic, growing from $83.4 billion in 2020 to $188 billion in 2022. Over three years, the companies amassed profits of $455.4 billion, equivalent to nearly $5,000 every second.
15 Oct 2023
Does the grammar really matter, is it that important?
It is a chat board where ideas and opinions are put forward not a written English test.
Nigh 1.2 million pounds raised by investors via the WRAP offer.
Clearly they are all of the same opinion and matters not if they spell 5hit with one t or 2 t's.
Regards