Member Info for Runner-Runner

Shows the discontent amongst the LTH's, I think.

So the directors took £130k of placing shares in the end.

Seen some posts about the raise being 10% dilution.

However, they are seeking to raise £26.8 million at 50p which, if successful would equate to a 20% dilution.

"£25-30million & they have only got away £13million "

How so?

They are trying to raise £26.8 million.

Wether they get it is another matter.

Every company needs money Jem. Please provide your rationale for the statements you made.

TIA

1. Raise at least £20m

2. Until they get to the the end of the next trial

3. Only then will AVACTA look at offers or JV

4. The raise has to be around 90p- 95p

Hi Jem. Please qualify the above statements you made, because at first glance it appears as though you have pulled them all out of your backside.

TIA

"Ice, I know, everyone knows, the platform works, that was known at the end cohort one.

Its about Efficacy. "

It isn't though Wyn. It's about the Platform.

The efficacy we are testing is of AVA6000. The results of that have no bearing upon the potential efficacy of other toxins that can now be used on our peptide.

Many other toxins can be tested using many other dosing regimes on our platform. Only AVA6000 itself is under the spotlight now for signs of efficacy.

The platform is ready for selling. We will be judged over the next few months on how valuable that platform is or isn't to Big Pharma.

And BigPurps. You didn't spell his name correctly. What with you being a professor of English and all? Who would "of" thunk it?

"Fact DX could be sold for plus 40mil"

Fact? Are you sure?

"This alone will see them through AVA6 phase2 and a lot of runway between"

We still owe HCI £41m, so not sure that helps much in any case.

"The tech will sell itself tbh."

That's alright then. Al can put his feet up and wait for his door to get knocked down. Lol

If we can do this, how long before someone else works it out? Get this data on every CEO's desk in the industry asap and start touting for business.

It's clear from the presentation and the language used around P1a that the mechanism of action is proven.

This means that we can (in layman's terms) stick a chemical onto our proprietary peptide and send it into the human body, knowing that only FAP will cleave the peptide and release said chemical in the body. It's the "Holy Grail"

That's it.

The Golden Goose has been created. Send it into the body clutching the chemical of your choice and it will lay its golden eggs wherever it encounters FAP within the body.

We are choosing to send it in loaded with Dox. Getting that to market is not cheap and will take much more time to generate revenues for us.

The opportunity however is to pimp out the Goose to the highest bidders. That opportunity exists RIGHT NOW.

Efficacy data for AVA6000 is NOT REQUIRED for other companies to attach their chemicals to our peptides and give them a try. Their chemical would be distributed in FAP-rich areas of the body, it's "unequivocal". Further efficacy data for AVA6000 is only relevant to us since we are choosing at the moment to keep it to ourselves.

What is perplexing is how confidently, consistently, and proudly AS talks about his Golden Goose and how he turns to mush at any questions about the commercials. If he truly believes his rhetoric around the science (and I believe he does) why can't he pimp out his precious Goose to the highest bidders - RIGHT NOW!?

I just can't square that circle.

"Does it even have to demonstrate efficacy if it’s proven to be Dox at the tumour?"

No BBB. This part of the trial was only ever supposed to be about safety and tolerability. Hopefully what the data will show is how much of the dox gets cleaved around the tumour site and how much is found in the tumours themselves.

It should follow that the dox cleaved from AVA6000 puts a higher proportionate concentration of Dox into the tumour than the random cell-killing properties of straight dox. Hopefully, proof of this will come from the data.

indeed bitl.

avacta aren't boosters. however.

2.5 years of a "data rich" study that as has described as "remarkable" and as being on the verge of a "paradigm shift" in oncology.

this is his moment to shine on the world stage. if the data backs these bold claims, then he has an extremely valuable asset to sell, 6 months after entering the "commercial phase". he should be boosting the **** out of it on wednesday.

if the data doesn't stand up to scrutiny or if we get some wooly can being kicked down the road again ......................

the sept 19th rns was, in my opinion, the greatest rns in avacta's history.

the data rns or release in the presentation on wednesday, should surpass it.

Wow VR. It's like you got up on a Sunday morning with an irresistible urge to show everyone how stupid you are.

Hey presto!

Mission accomplished.

You are enough to put anyone off buying in here Ria. The ridiculous amount of pumping posts you have made on here today is a huge red flag. Why would you need to post garbage every minute or 2, all day long?

Admitting you don't understand is OK Sheepy.

What part of the science are you failing to grasp Sheepy?

We have been pumping lethal amounts of Dox into patients for over 2 years. The absence of the usual toxicities is "remarkable". Remember the usual toxicities present themselves in horrific ways in patients at just normal levels of Dox. We have started putting 3.5 times the amount of Dox into patients, which usually causes horrific side effects, which can't even be administered to many patients - even at normal doses.

The Fap cleaving chemistry is targetting dox into the tumour and leaving healthy cells largely unscathed.

Pre|CISION "works" as intended.

Forget Dox for a moment and hence AVA6000.

Pre|CISION "works". Think about that. Think of the myriad of other cancer-killing "warheads" that could be attached..

This is about owning the rights to a Fap targetting platform biotechnology, not a single limited drug. This is where the value lies.

It is safe - proven.

It works as intended - proven

It delivers the warhead to the intended target - proven

It has shown signs of efficacy - proven

Right now, that is about as good as it gets.

"Seems really odd"

The only thing really odd here is you Sheepy.

It's the new name for Omega Diagnostics

"I hope that the presentation puts this to bed, I am after all an investor (but not a mushroom)."

If it doesn't "put it to bed", it seems (due to your terrified concerns) that you will have no option but to sell out asap. Hoping there is no mention of it for all our sake, as you will have no credible alternative but to sell and won't need to post on here anymore will you?