Roundtable Discussion; The Future of Mineral Sands. Watch the video here.
When's the BFS due?
Ah, good stuff. Thanks a lot
Hi Daprophet thanks. Yea its Meelie's comment ' who's 90 days is up on Monday' that I'm confused about as Q2 doesn't end for another 2 months so I'm wondering if they have a certain amount of time to publish the results after the collect the data ? I'm not sure
Hi Kevin thanks for your reply, i first invested march 2020 so been on this thread a while, mostly in the early days but kept pretty much up to date since - having said that there's clearly a slight gap in my knowledge which is the 90 days -what's the significance of this ?
Should prolly know this but what's the significance of 90 days ?
GTFO pal doing my head in
Anyone know when the results are out for the home trials ?
Anyone know why Google sp says 170 but LSE and HL say 130 ? Is it that google is live and HL and LSE are lagged ?
There's not even more sells than buys lol volume ratio sell to buy of 0.86
Not really, still made a small profit if you'd have sold this morning at 75p and bought back this afternoon at 70p
That's from the copd and asthma trials nothing to do with the covid trials
There isn't two ACE2 receptors. mRNA is the precursor to a protein, and gets turned into a protein... so when he says "The data in the paper are predominantly for ACE2 mRNA expression, not ACE2 protein expression – these do not always reflect each other. “ he means that not all the ACE2 mRNA that the authors used as a proxy marker for the ACE2 receptor does in fact get made into the ACE2 receptor
Upon further thought I have realised the error I made in that logic. Lol
I did suggest this the other day - although upon further thought if the whole point of SNG is offer IFNB when you have stopped producing it yourself then I'm not sure that increased ACE2 would create an increase in IFNB production in parallel.
Nevertheless, his answer raised some reassuring points and I feel much more secure, great work Miggy !! Cheers for that
Oranges and Rahulrajas,
Theres nothing wrong with speculation. You don't need a degree in medicine to logically follow the studies that come out and try and formulate what's going on to give you a better understanding of what you're investing in. If you want to follow SNG in blind faith then you do that, but there are quite a few investors on this board that want to read the studies that are coming out and discuss their implications. No one is claiming we know more than the scientists at all. If you don't want to partake, don't comment
I'm not offering any new information on what is going on, I'm offering an explanation. It's already been shown that IFN DOES increase ACE2
That's possible JM4910 yeah but we don't know that the effect isn't more severe in sars-cov-2 as opposed to sars-cov !
It does loads of things Rich like cut viral dna, stops host cells being able to manufacture protein, stimulates programmed cell death etc etc I read theres like 200 ISG's such as genes that are turned on by IFN to attack the virus in various ways such as the above
Yes that's my understanding Jack. However this effect of IFN doesn't just exist for no reason so I was wondering whether, perhaps before the virus learned how to turn off IFN prod, it was beneficial to have more virus enter lung cells as it resulted in more IFN production that would overwhelm the virus
Some good points but I hope you can understand I'm reluctant to just have faith that everything will be OK if I can help it!
Yeah it does do a lot of things to curtail the virus which is great but if it does something bad like raise ACE2 then I would like to understand whether this is a problem or not.