Member Info for RayPointer

My favourite comment was

"These people are psychopaths do not take this vaccine...."

Well done miavoce

I'll second that Wild.
Lindy has devoted her whole career to perfecting her science.
That's a life mission not a life style.

"The prototype is a tiny - and harmless - gold bullet coated in DNA, which is fired under the skin by compressed gas."

That suggests to me that the harmless gold bullet is a nano particle.

https://www.sciencedirect.com/topics/chemistry/gold-nanoparticle#:~:text=Gold%20nanoparticles%20(AuNPs)%20are%20small,Metals%20for%20Biomedical%20Applications%2C%202014

I make it S****horpe rather than Goole

But it doesn't have to be an equilateral triangle, Burnley Technical College could be in the running.

Perhaps Nottingham and Manchester are looking to form their own golden triangle.
But what is to be the 3rd point of the triangle? Could Rat's favourite Keele be in the running?

The Manchester Uni article could have been written by Lindy herself.
It summarises Covidity almost exactly.

Manchester Uni does not count, it is well outside the Golden Triangle :-)

It would be great to see Lindy giving the interview.
I'm invested in Scancell but I'm afraid another CH interview would send me to sleep.

Morning all

But the idea of collating SH questions and the publicising answers does have merit IMO

The dental instruments are now on 2 metre poles

If it is TCells that are the prime players in seeing off the virus, then the Scancell approach may be in pole position.

Immunobody creates up to 100 times of the normal TCell avidity.
Memory TCells seem to play an important role.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980353/

"To prevent recurrence of melanoma it would be ideal to stimulate memory responses. In animal models, SCIB1 stimulated memory T cell responses that continued to increase in avidity as the T cells were selectively recruited into memory.19 Similarly, in this current study, patients have shown stronger and broader responses following extended treatment with SCIB1. All patients on continuation responded to all four epitopes after five continuation doses at 21 months or after 10 immunizations; this suggests that vaccination for the prevention of recurrence should continue for at least 2 years post-surgery and that maintenance vaccination should be considered as it appears to improve the strength and breadth of the T cell response to vaccine-encoded epitopes. The former maybe related to memory but this is difficult to assess as we did not phenotype these responses. The latter may indicate de novo stimulation of new populations of T cells."

Well not everybody thinks that it is 1.

https://en.wikipedia.org/wiki/Zero_to_the_power_of_zero

Tumours were mentioned in the patent description.
I think you would lose your bet nom

"In all, 13 men still complained of poor memory, personality change, irritability, or depression after four years."

I this about the SCLP BB?

Sick joke Rats

And can we tell what this guy had for breakfast?

Sorry it is scib2 that has 16 targets.

Thank you for the link LL.

It is very relevant to the work Lindy is doing. Lindy will be trying to find the best targets(epitopes) for Covidity and she will be reading this and other articles to help direct her own research in the right direction.

Immunobody vaccines can carry multiple targets (scib1 has 16) and this article suggests that there are plenty to choose from. I would imagine that the work involved in target selection and resultant animal testing is similar to that for tumour targets. This is work that Lindy and her team are very skilled at.

Thanks Bermuda
I see what you mean

https://www.ipo.gov.uk/types/patent/p-os/p-journal/p-pj?startYear=2020&startMonth=June&startDay=3rd+-+6837&endYear=2020&endMonth=June&endDay=3rd+-+6837&filter=scancell&perPage=10&sort=Publication+Date