RE: Hold firm7 Jun 2024 15:30
So, if I am correct in thinking - Boehringer Ingleheim, whilst trialling Zealand Pharma's Survodutide (under development for the treatment of non-alcoholic steatohepatitis (NASH), liver fibrosis, type 2 diabetes and obesity) they found during sub-analysis that up to 64.5% of adults with fibrosis stages F2 and F3 (moderate to advanced scarring) achieved an improvement in fibrosis without worsening of MASH (Metabolic dysfunction-associated steatohepatitis - inflammation of the liver caused by excess fat cells in it). Could Aptamer Group's Optimer now be used to specifically target fibrosis??, as mentioned in the April RNS "it's Optimer binder against cells associated with fibrotic liver disease, developed for targeted delivery of therapeutic payloads to fibrotic liver disease, has been shipped to a top 15 pharmaceutical company for evaluation in their own therapeutic applications".