Member Info for OAMOT

Isn’t it a 6 dose regime administered in 3 week cycles? So 15 weeks in total. That would mean we are still 2 weeks ish from the earliest date to finish the increased cycle assuming it began immediately after the RNS saying it was moving to DE? If they’re measuring toxicity as main measure then normal dox is quickly out of the body I think (?) so results may only take a short time from final dose but might they need to wait longer for results? But no news is good news so does it matter? If they keep going it means it is working at this phase (nothing like as toxic). The fact those timings mean it’s still going after 5 doses, which is past normal MTD based on the current dose level, means unless it is also non toxic in the tumour it’s going to be a winner. All just based on my understanding so could be off the mark.

I could be wrong but I think he said EU HUA would make these markets accessible with relatively few hurdles? So hopefully HUA comes soon. Which I’m sure it will.

It isn’t positive or negative. The individual may need the net profit (15-20k) for a personal reason now, so it is totally neutral (a bit like AS selling to buy a new house, not positive or negative just an immediate personal need. . It could be negative as you would sell any asset you thought was about to fall, especially if right now it has profit in it. Or it could be positive - if you though a big rise was coming finding the cash to exercise now saves loads of tax. But speculating is fun and passes a Friday afternoon when there is nothing concrete to talk about.

The answer is probably in the tax treatment. If these are unapproved options (not sure they can be EMI shares - the section is EMIs and unapproved options) Income Tax is due on the gain when they are exercised and capital gains on any subsequent growth after exercise. As income tax is higher than CGT you would exercise now if you expected the price to rise. So the 30k gain now is taxed at 40/45% but future growth at CGT rates (20%). If you waited to exercise and the price was higher then you’d pay income tax on more of the gain and lose 20/25% of the profit in tax. All irrelevant if the individual is selling immediately. But if they aren’t then you exercise as low as possible I think to save tax. So if you expected prices to rise you’d exercise asap. Not a tax adviser so don’t go crazy if I am wrong!

I don’t think them resigning has any relevance. The RNS says avacta appointed BDO after a tender so KPMG were exiting at avacta’s choice. I think it is then standard practice the outgoing auditor resigns (as opposed to being removed by the company) to make way for the new.

They are definitely too small - J&J has over $30bn in cash at end of Q3.

I’ve not got time to search for that. But as I am researched in this share I did spot immediately that the list you shared was from before avacta’s approval date. So to help discussion, and avoid anyone thinking that proved avacta couldn’t sell in Europe, I thought I’d make the point. It didn’t take a lot of effort (far less than searching global approved product lists) to give the avacta approval date.

Agent B having spent all the time putting that together you will also know that the date the EU approved products lost you’ve provided the link to was updated is one month before Avacta announced EU approval? Not sure why you’d go to all that trouble to give everyone those links but forget that key point…….

If you are 60% down you must have bought at the very top - quite recently. Surely you didn’t buy at 280 recently based on what was said last summer before the fund raise?

85% of adults have taken a dose of the vaccine. Are more than 15% of deaths unvaccinated? If so then not taking the vaccine make a you more likely to die from Delta. That is without doing anything to weight the fact vaccinated are older and therefore have a higher covid risk.

It isn’t new auditors. KPMG Leeds have audited avacta for years.

And I’d expect a small pharma like avacta to have resolutions to allow fund raising so they can do it if needed. It is probably there in some form every year.

The other allows either a right issue or share buy back up to 5% if I’m reading it right.

I’d be pretty confident none of it means anything. Just confirming standard tools to let the BOD run the company without an EGM.

Do you think those large late reported ‘sells’ are buys?

Worth not with

Well so far a business with just north of quarter of a billion.

It reduces your liability. Everyone has got that bit. The point is you save £1 or £2 in tax on profits elsewhere for every £10 you lose. So you don’t make a loss on purpose because you are still losing £8 or £9 out of every £10 you lose. You just Crystallise one sometimes when you’ve profits elsewhere. It reduces you loss slightly, but you still take 80 or 90% of the loss. There is only one way to make money from a share price falling. A short. Unless you are shorting you aren’t profiting from a fall to 102.

Everyone gets it. The tax rules are very simple Nobody gets the bit about waiting for 102 to sell? There are no investment or tax reasons which let you gain from selling an asset you own that’s worth 110 today for 102 in the future.

Really? And clients pay you to deliberately lose 10k to save 2k in tax? Offsetting losses is an obvious part of investing. Deliberately making a bigger loss to do this is insane. I’d love to see you compliance manual.

But your plan is to lose £4 or your money to avoid £1 of tax. Will you manage my money please?

Many times. But if I offset a 10k loss I save 20% tax on a gain or 2k. You don’t deliberately lose money to offset a gain. You are still losing 80% of your money. It’s not an investment approach for me but each to his own.

I almost never post on here, in fact I only have once. That needs a response though. You want to wait deliberately for a lower share price to sell? You can sell. Ow around 110 but want to wait to sell at 102? I understand offsetting losses for CGT etc but never heard of the concept of deliberately losing more money for tax reasons. Can you help me understand?