TREM212 Aug 2020 17:51
'Antibody aids immunotherapy in clearing out cancer in mice'
'The team tested the idea in mice with sarcoma. One group received an antibody that blocked TREM2, one group received a checkpoint inhibitor, another group received both together, and a fourth group received just a placebo.
As expected, the control group’s cancers grew steadily. The mice that received either treatment alone saw their tumor growth slow down, and in some cases reverse. But strikingly, every mouse that received both treatments together had their cancers completely disappear. Another round of experiments, targeting colorectal cancers, had similar results.'
https://newatlas.com/medical/antibody-immunotherapy-cancer/