Member Info for NFTs

What we can see from the dosing is that lower dosing has near on no bad effects at around cohort 3,4,5 areas.

Like any disease cells regrow so if you hit them quicker then they cannot grow back fast enough so reversing the process of cell growth.

Now a 69yr old patient has been I believe on cohort 3 since Feb 23 thereabouts on 3 wk dosing which as we know is not quick enough to get that reverse action working properly.

Therefore it is truly remarkable that it’s also working on these 3 wk dosing intervals so 2 wk dosing is going to be one hell of an improvement in action.

With a 45min half life then we know that dosing even quicker will be possible imo. Who knows weekly / every other day etc at lower dosing will obliterate tumours. We have seen precision hits selectively FAP and delivers Dox efficacy splendidly.

You are looking at the holy grail of chemo precision right now and upon the 2 wk data release I think that will be enough to get our first Major to come fwd with an offer.

With 3996 data due out also and IP protection being primary then the multi billion £ assets will come alive.

It’s a very big year ahead for Avacta and those loyal investors here.

Ignore the city paid spivs playing the spreadet CFD game. They know nothing. Their luck 🍀 is nearly up ;)

I had been warning that this is most likely outcome since 2022 but always got shot down instantly by a few here who continued to try buy themselves out.

This company showed no success in 22 and it should have at that point. US flop EU flop. Small contract wins flop even a so called NZ air deal which imo was done on a special rate to try hide facts.

TB is a flop that cost shareholders their money which he simply didn’t care. The only thing he wanted was to try get his HIS baby afloat at any cost. Now sells out to Chinese. I don’t think that’s a surprise either imo and all been played out to escape after he realised taping the UK market no longer works like he hoped. Bad advice all round here.

“ NFTs

Posted in: EISB

Posts: 458

Price: 1.025

No Opinion

You were warned25 Jan 2024 12:14

I explained that the business plan is awful and it still is until they drop prices lower than fever and grab volume. Tony’s brand is good but the direction of exclusivity is the problem. They need to drop expectations and think about surviving. Unfortunately that imo won’t happen.

“NFTs

Posted in: EISB

Posts: 386

Price: 1.225

No Opinion

Few million required3 May 2023 15:25

The issue is funding and nothing to do with any poster stating the obvious. If people are trying to average down be prepared as 2 million now will be more than 50% dilution of the SP.

I am surprised that management have sat on their backsides to raise capital so late here in this market. That’s exactly what happens to others that shut the doors. Too little too late springs to mind here. Protect what you got as managers are not looking out for you here they are looking out for their pet project which was supposed to find cash easy here over on the UK main market!!! Oooops”

It was finished in 2022! They have kept the shocking truth being said but the facts on figures and reality were there in black and white but the management were only in the UK market to try last chance saloon to extract cash to fill Burts personal dreams but he was a dreamer and too obstinate to realise his dream was just not possible in large form.

It’s terrible how a NZ company can list and hide facts to keep taking money from UK investors. It won’t be properly investigated to hold BOD to account and the Chinese will ensure Burt gets payback imo.

Shocking and anyone with considerable cash in here should form a group to go after BOD to ensure they also pay the price properly for what they have knowingly done and hidden over this last period to try escape.

For example

https://www.astellas.com/en/system/files/news/2020-02/20200220_en_1.pdf

Too many newbie’s trying to sound like they have a clue in what is going on here.

Worth checking out the below to realise how close they are to getting targeted therapy approved for certain indications.

precision conjugates can get approved quicker than new drugs. This is because precision conjugates are often based on existing drugs that have already been approved for use. This means that the safety and efficacy of the drug has already been established, and the focus of the approval process can be on the new delivery system.

In addition, precision conjugates are often designed to target specific diseases or conditions. This can make them more effective than traditional drugs, which may have a broader range of side effects. As a result, precision conjugates may be approved for use in specific patient populations, which can reduce the time it takes to get them to market.

Here are some examples of precision conjugates that have been approved quicker than new drugs:

* **Brentuximab vedotin (Adcetris)**: This precision conjugate was approved by the FDA in 2011 for the treatment of Hodgkin lymphoma and systemic anaplastic large cell lymphoma. It was approved based on a clinical trial that showed that it was more effective than the standard treatment at the time.

* **Trastuzumab emtansine (Kadcyla)**: This precision conjugate was approved by the FDA in 2013 for the treatment of HER2-positive breast cancer. It was approved based on a clinical trial that showed that it was more effective than the standard treatment at the time.

* **Enfortumab vedotin (Padcev)**: This precision conjugate was approved by the FDA in 2019 for the treatment of urothelial cancer. It was approved based on a clinical trial that showed that it was more effective than the standard treatment at the time.

Overall, precision conjugates are a promising new approach to drug delivery. They have the potential to improve the efficacy and reduce the side effects of drugs, which could lead to better outcomes for patients.

sorry for those losing money but i made my opinion very clear here for last year and a bit. they had failed to change tact to higher volume lower margins with a cheaper product outlook. this cottage style mantra of ultra premium around the world without a lot to **** in was a dreadful business plan. burt has been at this for nearly 10 years prior to coming to uk market to milk it. problem is he was 10 years too late and uk market now doesn’t play ball like it did.

you cannot say you will possible become profitable in a year or so when your whole business plan revolves around investment for growth. it will never make a profit on this current business plan and i said that ages ago.

it was doomed unfortunately to ever succeed when it started to lose mcap it couldn’t raise to carry on. i hasten to say covid shipping prices did kill it quicker but it was going to die.

fevertree cheaper and frankly nicer!

aberdeenman again finds another howler of a company lol 😂

It always been coming but it really is now a matter of waiting till that first major goes for a bid and on that bid will come the starting gun for a massive bidding war.

This cheap solid tech is the way to go for a generation or two with all the other warheads they will attach,

Anything less then 10 bil and you will be a loser ;)

you can tell it’s about to lift off as the city have their usual posters working overtime.

as absurd that that seems it’s obviously true here.

really sad people to try ear money spamming message boards with constant ****e

I’ve a few 100 thousand votes which is only a decimal of a percentage here and I’ve had a huge hit in my financial position but I absolutely strongly believe that any of this money raised now is going to deliver a huge return. Obviously I’d loved to have hindsight and sold and bought back down here to get way more shares and be laughing but I didn’t.

I’m 100% certain on outcome here and 100% certain he can deliver that for us as shareholders.

I also wished it had been placed higher but it hasn’t. I can deal with that if confidence in the company and product.

This has everything it needs but a sale to a major. That will be what comes sooner than expected.

Lucky for anyone who can load up at these levels.

No Redshoes 👞

That’s not why they have only done 10%. And yes you were saying they had plenty of funds to last.

Simply if they tried more the price would been a lot lower and the risk for those who will be dumping those shares over coming months will struggle.

Every year now this share has a large holding being dumped. When that finishes they will then raise the next tranche and so on. Sort of like Lanstead but just more conventional and easier.

🤪

I’m sorry but I’m not the one being bitter!

Perhaps you need a mirror also.

Hard for some to reflect on the fact they got it wrong here.

Really?

I do t remember any of you saying there is a placing coming.

All I ever read is wonderful stuff coming going to be great same rubbish every month after month. Yet here you are after two years more diluted less cash than at any previous time with works required no deal anywhere near and requires orphan status to try get them to become interested.

They will have the option to allot more stock after the AGM which they will use in September this year to keep them going till next AGM. Miracles can happen but no new developments here apart from some worthless updates on NXP004

You haven’t got a clue what I have or haven’t done.

The presumption and arrogance is rife. The failure to see is your weakness

Not sure why you want to keep discussing other shares here as you keep mentioning Avacta.

But you are absolutely correct that the market are corrupt as we all know. It’s basically about trying to miss the bullet and catching it after the drops if IF the companies are investable.

So when comparing since you want to keep talking about AVACTA then it’s a little bit childish.

AVACTA is a huge huge huge potential with assets already close to being able to sell for billions to BP yet here we have something that has been trying for years to get one thing over the line properly and that being NXP002. The rest is worth few grand as you see with NXP001 etc now gone.

It has no office no proper management absolutely no income but bleeding shareholders every 6 to 12 months and now on its last throw or so of the dice.

Not sure you can even begin to compare lol

I mentioned that the placing of the last chunk was never notified and that same institution who held that stock dumped the other day knowing they could grad a load more cheaper.

Wake up and see that this is being played and the directors don’t care as they have no choice otherwise those who take the placing stock won’t partake.

Now we see why they do!! It’s all so corrupt isn’t it!!

Being able to accept you get things wrong is an important part of life.

One two here who throw jibes at people who mentioned this coming saying they are wrong and deflecting it with insults and jibes and false accusations should realise that they are the ones who are having trouble to accept different opinions.

I’m not always right but I was absolutely right that this was inevitable.

Perhaps learn to accept but you will never and will always throw retorts back as you always think you are right.

I can add and sell stock as and when I like. Thats my business not yours.

Funny as who were the ones saying that!!!

Ummmm mirror mirror on the wall.

At the one that states Karma and how it comes back to bite.

You have no idea 😂

If you can look at things without being emotional and personal I have been stating the fact they will have to raise therefore being invested was a risk of dilution. By all means do your own things but certain significant know it all’s here persists in being personal and blinded.

You were warned and I was right.

They have nothing tangible for a long period and it will continue to stagnate as cash goes out and nothing comes in.