RE: £224 Nov 2020 21:05
Technick, many thanks for the interesting insights into virus mutations.
I have a background in conducting clinical trials and whilst I appreciate that nobody wants to be a killjoy, I am flabbergasted at widespread unquestioning acceptance of the vaccine efficacy claims. The key issue in a trial, for statistical predictive power, is not how many subjects you had at the start but rather how many end-points you have to compare between the 2 groups. In the vaccine trials this appears to be between 90 and 130. If you stratify this for different age categories or co-morbidities you're left with less than a dozen in each strata. This is not good enough for robust conclusions. In my view, things will start to unravel once we have data on 100,000s of people, may be in about 6 months.
The other elephant in the room that none of the studies have addressed, is how long any immunity lasts. There have been published studies, albeit limited, that suggest individuals being reinfected after a matter of weeks. Anything less than 1 year would be disappointing for a vaccine. In any case, to determine the length of immunity in a meaningful population you would need continuous mass testing globally for a long time.
I am sure LTH holders of GDR will be rewarded for their patience.