Prospectus5 Aug 2020 21:46
I've not seen this posted so apologies if I have missed but within the fundraising RNS is a link to the commercial prospectus that accompanied the sale. It provides a neat summary of the key areas of business (updating some areas from the annual report). It is available at: https://www.sec.gov/Archives/edgar/data/1723069/000121390020020182/ea124966-424b5_tizianalife.htm#T24
Eg Stemprinter summary therein.
StemPrintER is a multi-gene signature assay intended for use as a prognostic tool in patients with estrogen-receptor positive ER+/HER2 negative breast cancers. This in-vitro prognostic test can be used in conjunction with clinical evaluation to identify those patients at increased risk for early and/or late metastasis to help physicians distinguish ER+/HER2 negative patients. Two posters were selected for presentation at virtual ASCO 2020 Conference. One demonstrating the superiority of StemPrintER stem cell based genomic prognostic tool versus the market leader, Oncotype DX, in predicting recurrence in ER+/HER2- postmenopausal breast cancer patients was selected for discussion session. The second poster describing results on prediction of distant recurrence using a next generation StemPrintER model, named SPARE, presented in a separate ASCO session, showed even more refined accuracy than standard clinicopathological markers in predicting risk of distant recurrence. Both posters were authored by a team of scientists from the European Institute of Oncology in Milan, and the head-to-head comparison of StemPrintER with Oncotype DX was conducted in collaboration with the Royal Marsden Hospital and Queen Mary University in London.
On July 1, 2020, we announced plans to continue with “demerger” of the StemPRintER© technology and spin-off into a separate company. This event followed announcement on May 29, 2020 of results from a study showing that StemPRintER outperformed Oncotype DX in 10-year risk prediction in more than 800 ER+/HER2- postmenopausal breast cancer patients in the analysis, including in lymph node-negative (N0) and 1 to 3 lymph node-positive (N1-3) patients.