Member Info for Matml74

Based on 300 shares traded.... I wouldn't bother.

This rns is likely priced in by existing shareholders but the awareness of SNG particularly in US via Activ-2 news late Friday should bring new investors and further price rises. This company is still undervalued with respect to the upside. Should be north of 500ml MCAP.

Spinnaker, Re: nebulisers - This has been fully considered and is the reason for the shift to Aerogen one-way nebuliser I believe. Aerogen have produced this document specifically around this issue including for at home use.

https://www.aerogen.com/wp-content/uploads/2020/12/ICS-guidance-for-nebulization-during-the-COVID%E2%80%9119.pdf

and more evidence here....

Pre proof for Cell journal in interferons

https://www.cell.com/trends/immunology/pdf/S1471-4906(21)00027-2.pdf

“ Despite the above concerns, prophylactic use of IFN-1 (or IFN-III) might have potential; a recent uncontrolled exploratory study on hospitalized COVID-19 patients with mild disease found that administering nebulized IFN-?2b reduced the duration of detectable SARS-CoV-2 in the upper respiratory tract, and also reduced the concentrations of both IL-6 and C reactive protein (CRP) in blood [23].”

I know Mac. This is yet more evidence of the effectiveness of interferons. There is now a huge body of evidence around interferons that needs to be considered by the authorities.

Come on MHRA get your heads out of the sand!

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(21)00023-7/fulltext

“Findings

Interferon-beta-1b was associated with an improved composite outcome (OR=0.55, 95%CI 0.38, 0.80) and earlier discharge (-8.8 days, 95%CI -9.7, -7.9) compared to those not administered interferon-beta-1b.”

“Our findings support the early administration of interferon-beta-1b alone or in combination with oral ribavirin for COVID-19 patients.”

UK have waited for 70k people to die this winter before thinking about accelerating treatments. What planet are these imbeciles on. They were warned about this is last July in the ‘Preparing for winter’ report. They chose to ignore it. The UK government dropped the ball on treatments last summer and are now trying to make amends but it is too late for all those that lost their lives this winter.

They celebrate a 1 in 25 improvement of so and so a drug because it came out of recovery trial. Seriously 1 in 25! God help us if that’s the best they can do. That is not going to change the way forward in this pandemic.

This will turn out like the EU/UK vaccine issue. UK will be up in arms when US has bought up all of the SNG supply. The writing has been on the wall since last October when it was clear it was the US getting behind SNG. Sir Holgate’s frustration clearly shows that the UK have not changed their track and will explore everything else but our drug. UK gov have taken their bat and their ball and they are going home and they are not going to give SNG a look in.

God bless America :-)

Rant over!

Seriously. Not the move I would have made but each to their own.

Josh, Venrock still hold 2.2 million shares. I think they are involved in something for sure.

Great news. Well done RM and all the SNG team.

CE marking needed to sell into Europe.

It continues to be a requirement for goods placed on the EU market to have the CE mark by way of confirmation that they comply with EU product regulations.

"Export businesses will therefore need to ensure that any mandatory third-party conformity assessment is carried out by an EU-recognised notified body where necessary in relation to goods that are intended for export to the EU27 countries after 1 January 2020. If you are using a UK approved body for this purpose, you should check with them whether they are taking steps to enable you continue to export to the EU without needing to switch to an EU-recognised notified body, and seek appropriate guidance from them in this connection."

https://www.gdlaw.co.uk/site/blog/our-services/EU-UK-Trade-Cooperation-Rules-of-Origin-CE-mark-UKCA-mark

Tom,

Newcrest exploration report week of March 12th. They publish every 6/7 weeks.
Surely get the second set of Scally results before they start next campaign in March.

correct.

We did start the week at 179 so pretty sure no leaks involved. The SP has been held in a range since Activ -2 news and has not had the rise that it should of from that RNS so a rerate might be on the cards today.

Hopefully all goes well for them Hull!

Unlikely Mac. That would take an added layer of genetic testing that isn't widely available at this point. Also it doesn't really fit with the statement that there is a specific list of people excluded, rather than included.

It is more likely some of the same exclusions as P3 like:

History of hypersensitivity to natural or recombinant IFN-ß or to any of the excipients in the drug preparation.
Females who are breast-feeding, lactating, pregnant or intending to become pregnant.

"We’re talking about the end of a mine and now we’re talking about the beginning of a great new mine, right? It’s chalk and cheese. It’s incredible."

Wow. Thanks Paddy! That is a really positive statement of where this is heading.

https://tools.morningstar.co.uk/uk/stockreport/default.aspx?tab=0&vw=st&SecurityToken=0P00007OXV%5D3%5D0%5DE0WWE%24%24ALL&Id=0P00007OXV&ClientFund=0&CurrencyId=BAS

7 million shares!

Chris, Yes I think we will push higher once the US gets wind. More importantly we have a clear path now to EUA.

• 220 patients to recruit in the US where infections are still high
• SNG001 has to beat placebo on this Primary Outcome measure ......

Duration of COVID-19 symptoms (Phase 2) [ Time Frame: Up to Day 28 ]
Symptoms: Fever or feeling feverish; cough, shortness of breath or difficulty breathing at rest or with activity; sore throat; body pain or muscle pain/aches; fatigue; headache, chills, nasal obstruction or congestion; nasal discharge (runny nose); nausea or vomiting; and diarrhea. Each symptom is scored daily by the participant as absent (score 0), mild (1), moderate (2) or severe (3)

I am very confident that can be achieved before the end of March!