Todays science on interferons6 Mar 2021 09:55
More science .....
https://www.nature.com/articles/s41392-021-00526-2
“ The concentration of interferon-a (IFN-a) in the serum of patients with COVID-19 increased significantly compared with that of the controls in an additional cohort of 215 patients with COVID-19 and 106 controls, further suggesting the important role of the IFN-I pathway in the immune response of COVID-19.”
“IFN-I is crucial for promoting antiviral defenses through the induction of antiviral effectors.33 The production of the multifunctional cytokines IFN-I (IFN-a and IFN-ß) is one of the earliest innate responses induced by viral infections.33,34,35,36,37 MAPK pathways have roles in IFN-I production, viral replication, mucus production, and T cell responses, all of which are important processes in infection airway disease.38 We found the serum IFN-a levels of patients with COVID-19 are higher than that of normal controls, and the highest elevation was found in moderate and mild patients, which may suggest that an increase of IFN-a in the blood is beneficial for killing SARS-CoV-2.”