Member Info for John117

Not sure about that, I don’t think there would be the resources or much appetite to flog a dead horse.

I guess. Massive positive as you would not extend The trial like this if you had not seen any benefit. Really pleased with this development.

ShareSting, did the trial amendment get posted after clise of business do you know? Surely that information must be in an RNS in the morning. Bit annoying as I was ready to top up today but decided to wait until tomorrow (limit order not hit).

Don’t look back in anger

My guesstimate is they should be out/nearly out of placement shares. I would say tomorrow in fact. However we don’t know if anyone else is taking the free money. Hopefully not. Good news will make it academic anyway.

ShareSting, I don’t see why we would need to join ACCORD, like you say we are further down the track. It would be a step back, it makes no sense. We just need to finish the trial we started, that’s the quickest way. Also that Bre drug had shown benefit in vivo, but that’s a long way from benefit in humans. My understanding is that MOST drugs that show benefit in vivo do not carry that over to human trials. It’s a head scratcher to me as to why we are sat at a market cap of 80m. Can’t last.

Ok thanks Ghia. I’m not desperate for more I’m already massively exposed but I’m up for buying more in what I think are dips. Hard to know though. I kinda thought we wouldn’t get news in the early part of this week as we had that video release last Thursday. My guess was Thursday at the earliest. I also think the timing of that video was to help stabilise the share price amidst some placement shares being cashed in.

I wen to buy some more when google was showing 52, but the ask was 54. Which is a big enough spread! So I haven’t bought more today yet. What’s the cheapest people have bought today? I saw it touch 51 odd earlier but now wonder what the ask was at that time.

I think your timing is pretty good here.

Best guess is we have to wait until the SNG trial is finished. Then anything could happen. I know we all want news, but it will only come when necessary, and that is not dictated to by the current share price fluctuations.,

I notice Tom Wilkinson is heading up the ACCORD initiative

I think it’s interesting they should tweet that now.

We only need a partial win. With no side effects a partial win will suit me just fine :-)

In a nut shell - it worked better with more severely ill patients. This only strengthens my opinion tbh.

Hi Forest, the summary of that article (10 minutes of my life I won’t get back):
“In summary, this study suggests for the first time that administration of IFN-ß by inhalation can enhance innate immunity both locally within the lungs and, to a lesser extent, systemically, thereby compensating for the IFN-ß deficiency that we have previously demonstrated ex vivo in the epithelium of patients with moderate-severe asthma (6). The possible beneficial clinical effect of treatment seen in patients with moderate-severe asthma that was associated with this enhancement suggests that this treatment may impact favorably on cold-induced asthma exacerbations. The trial was designed and powered on the basis of the entire mITT patient population; therefore, further adequately powered studies focusing on more difficult-to-treat people with asthma are now needed to test the hypothesis that IFN-ß is effective in this high-risk patient population.“

10 year I meant

Just read that article, what a load of tosh. He wants to use charts on a breakout company, and goes on about 20 year time scales when we are already over that here. And obviously pointing out liquidity is low, which is a good thing if things go right. SNG001 is also a unique and patented formulation not a rebrand. Muppets.

It’s in our favour, see the research paper.

Punit you are funny.

When you say failed to meet its end point, I think AZN made a commercial decision because they thought the market was too small (they couldn’t find enough people to test it on). AZN were wrong because they didn’t see the full potential IMHO.