RE: US Analysis on the importance of interferons9 May 2020 10:20
This is another compelling endorsement of SNG001 possibilities.
“ Despite virus replication, the host response to SARS-CoV-2 fails to launch a robust IFN-I/-III response, while simultaneously inducing high levels of chemokines needed to recruit effector cells. As a waning immune response would enable sustained viral replication, these findings may explain why serious cases of COVID-19 are more frequently observed in individuals with comorbidities.”
And
“ To determine if SARS-CoV-2 was sensitive to IFN-I, we next treated cells with universal IFN??and assessed viral levels at both an RNA and protein level (Figure S1B-1C). These data demonstrate that the addition of IFN-I resulted in a dramatic reduction of virus replication in agreement with the findings of others (Lokugamage et al., 2020).“
Note : I have only read the first six pages thus far.