Member Info for Ivyspivey

Not sure JB I can think of at least 3 Biopharma that had a AIM and Nasdaq dual listing all with Market caps lower or similar to SCLP.

Makes sense to me to consider it if results are very good and provides a good exit strategy for major SH if they want the opportunity

JB any threshold price on Nasdaq is immaterial to current SP as they would simply list as ADRs which will have a “ consolidated SP. But good to see publicity in a major Sunday and the Nasdaq but was the only new bit as far I as I could see.

Should have added “ planned” as part of official trial protocol

In response to your query the only official possibility of “ formal success” regarding the trial is this bit.

The Phase IIa expansion cohorts of the master protocol is designed with a Simon two-stage methodology, with an interim analysis for futility based on RECIST 1.1 ...

Normally an interim analysis would be in order of 75% of trial patients completed but as you can see this is only in the p2A bit so is in fact a sub set where the trial could be finished early.

This would be fantastic news but is some way off but any successful update would be most welcome as this would be indicative of progress so far.

Hi hope you are all enjoying B/H.

Not sure if this adds anything as from a couple of years ago but may be useful as background.

https://www.google.co.uk/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&ved=2ahUKEwi83NT4upr_AhXKRkEAHe7wB2gQFnoECDEQAQ&url=https%3A%2F%2Fwww.interpressnews.ge%2Fen%2Farticle%2F115008-statement-by-green-capital-and-zaza-mamulaishvili-aims-to-mislead-the-public%2F&usg=AOvVaw2h6t6vol6_dhHQkUv7XcLG

WTP there have been issues with BBC NW news this morning so we have had London and Look North today already so have not seen article on locally.

Hiwever I have been looking fir a few weeks so nothing on local TV AFAIK.

By coincidence I am in Widnes today :)

I know the Nomad had some issues with FRR ahead of the delisting but think it was the publication of the “ court documents” that highlighted some blatant misinformation that was the final step

Hi LL,
I honestly don’t believe that RM will be in the slightest bit interested in making a takeover bid for SCLP as they are an investment/ hedge fund and SCLP have many different platforms so making a complete takeover by anyone will be difficult.
The taking of control of Redx was a totally different situation and I don’t mean the diversified platforms are not valuable just they will have different value to different people not all to the same entity if that makes sense.

Hi ZZ it was my Friday ritual after coming back from the pub and the wife never understood when I seemed more keen to look on my I Pad than go to bed.
I have not checked the Cayman Court lists for years and she now says to me don't come to bed but there is nothing to stay up for lol

Yep Cleaner wishing you all the best and your health is much more important than any wealth this may bring you but they are nit mutually exclusive so May you and others enjoy a good chunk of both

Thanks Zeron it was Justice Kawarley and Looed yes still a way to go and unpredictable outcomes as the one big lesson here is to expect the unexpected but at least there is some ” Hope “ though sone will shudder at the mention of that name.
I have long given up on who is right in this scenario and view any return here as a totally unexpected but welcome bonus whereas others will be seeking redress and the promised return for all their suffering and there are I am sure some real tales of heartbreak here.
What prompted my post as well as checking in was my Friday night/Saturday morning ritual of checking the Cayman Gazette and Court proceedings for updates

Morning and thanks to all who have updated us with the latest developments and especially Looed.Despite the obvious increase in positive sentiment I won’t get too excited until some concrete news and a real willingness by FRR to engage with SH about the current and future situation.The real change that seems to have occurred is the now apparent recognition brought about by whatever means legal or financial that the main adversaries need to work together to secure sone type of outcome.I just wish they had heeded the words of the wise Judge in the Caymans( can’t remember his name) who tried to bang the heads together some years ago as may have saved all parties including the long suffering SH a lot of grief. Enjoy the w/ end all

The free trip to Legoland is the real prize as most of the goldfish die pretty quickly.
Jigger us a top class poster and does great research

Completely agree Burble that would remove any speculation about when updates would be given and keep SH regularly informed.Of course these planned regular updates would also be supplemented by the normal newsworthy RNSs which are subject only to the normal timeline.
SCLP have a broad enough pipeline to do this as does not have to be any more than a brief update as other Companys do.
It is just a feature of small Biopharma that only seem to think they need to keep investors happy by releasing material news or subject to normal interim and full results touchpoints

Johnny has given an excellent summary of the Modify trial and of course there can be an update at any time and we are all keen to know the latest news as we believe the Science will generate the game changing data.
Bojo I can only think of one AIM Biopharma that gives regular updates ie every time the dose rate increases and a different cohort is initiated and traditionally SCLP has never given what I would call regular updates apart from the normal FPI/LPO and the actual final results etc.
This p1 trial is a very comprehensive one with lots of different cohorts involving different combinations and indications and apart from the universal safety data presumption common across different cohorts the efficacy data will be based on relatively low numbers and I just don’t feel that SCLP will be keen to update the market until they are in a position to provide pretty conclusive data and to me that will be a while.
They also as BS says have an interim analysis as part of the protocol and normally if you have that you are pretty confident but equally it provides a planned analysis and prepared. update point in advance.
None of us can be certain but I just counsel against the ebb and flow of expectations that have been observed recently and during the Covid trial and am happy to be patient confident in the Science delivering the results which will rerate the SP but there is a long way to go imo.

Afternoon and not sure why people are expecting the next trial update to be very soon.
Traditionally Biopharma do not give ongoing updates on trial progress unless significant milestones are passed which generally happens rarely during the course of a trial.
I can think of examples where you do get more regular updates such as when the next cohort group happens but SCLP do not normally fall into that category.
I understand the “ anticipation” that some thought would happen at the time of the AACR meeting but normally SCLP waits until say a results reporting RNS which we can predict the time of or when significant news occurs.
There just seems a discrepancy between the expectations of some who seem to anticipate a “ running commentary” which imo is unlikely and the normal SCLP practice of issuing infrequent updates.
That is why when SCLP do issue an RNS trial update it is so worthwhile not only as it usually contains very good news but also they are conservative when it comes to updating the market.
Enjoy the w/ end but patience is the watchword

Thanks EE,
Makes sense and good to have your experience on board in explaining these situations.I find this invaluable when usually it is “normal housekeeping” but can lead to speculation both good and bad.

Morning EE,
I view of your experience I understand the historical bit but why do you think they have included the reference to funding.

The Board considered both historical practices and on-going funding requirements in this regar

Thanks in advance

Thanks Bermuda re the interim analysis bit and normally the case in later stage trials it would generally be at 75% stage rather than earlier but will have to wait and see

Yep footy a bit like dealing in shares.Ups and downs but stay in the game and get rid of the “ parasites”