Member Info for inanaco

Politics Politics and Politics .....

Give them a headline ............ don't look at the small print ....

this one

https://www.vaccitech.co.uk/phase-2-clinical-results-for-vaccitech-universal-influenza/

lets put Big Pharma into perspective ....... Block Buster "Keytruda"

Yet the success of pembro was anything but inevitable. It was discovered accidentally, by biotech scientists looking for drugs that would tamp down the immune response in patients with autoimmune disease, and would stimulate, not block, PD1. Even after a potent PD1 inhibitor was identified and recognized as a potential cancer drug, the research program had to fight for funding through two mergers and acquisitions. After the program finally wound up at Merck, in 2009, it was considered such a low priority that it was shut down and placed on the out-license list. A term sheet (valuing the program at next to nothing) was reportedly in place, but pulled at the last minute, as promising results from competitor Bristol-Myers Squibb (BMS) motivated a reconsideration of the mechanism.

so smart ...

43,551 is mine

so public information ref melanoma us the trial investigators name .. easy

so the way you word it has to be done very carefully so that Scancell itself does not get mentioned or a particular product

so instead of scancell use "University Group" .... DNA Vaccine ... rather than SCIB1 .... patients receiving a melanoma vaccine rather than using a direct name SCIB1

It’s an advert, spam, or promotes a specific product or service ...

in the rules

if nothing is on the market even a vaccine that is poor .... has value

snowflakes would happily pay for a placebo ...

they are now .. Nigerian Doctors are so smart

Ray they are probably fired at you at ballistic speeds ... which is how they open up cells .

careful folks ... A new Policemen on the BB ....

Supernintendo Ivy ...

labour MP's are paid 100% to sit at home and do nothing ........... chill lammy

its a Grant .......... not a stipulation that you will work for nothing ......... Jermey Corbyn is not in office

well at least my original concerns expressed about the Oxford vaccine that failed in Flu, and had a poor response in cancer has shown to have been not far off the mark ....

not great that ....

seems that its a partial response to the vaccine ... i would suggest from that data that the vaccine may impart some immunity in healthy people so that if you get the virus it may reduce the viral load, however in the over 55 group it may not help much

good find well done

commercialisation ......... of Covidity

1/ head of terms can be negotiated prior to

1/ get the animal studies done
2/ get the phase 1 data and full dose starting to feed through

at that point you will have a direct comparison of the effective Antibody generation against other developers

you will also get the Immunogenicity of the T cell response .......... and the vaccines ability to generate memory t cells

this is the point of divergence from low affinity vaccines and antibody only vaccines that our data should show clear differential

turn heads of agreement into a license ...........

Director ? but non operational ... (Non-Executive Director)

so is not involved in the day to day running ...........

that's fantastic news CC ... that they have "target epitopes identified"

so by next year ......... Immunobody for Cancer ......... could be manufactured by a not for Profit operation funded by the Government ....... after all Cronovirus will not be around for ever

Moditope is a different class and they probably will not have the set up for a specialist vaccine like Modi1

To build a factory based on an unkown format is going to be interesting .... they seem to be banking on the Oxford vaccine ...

LOL ....

Guess what they all start with a Plasmid DNA

Such therapies are based on using either adenoassociated virus (AAV) or lentivirus (1), both vectors being frequently generated through transient expression routes based on plasmid DNA as a starting material.

Thanks BJ ....

ImmunoBody® is a DNA plasmid that encodes a human antibody or fusion protein engineered to express helper cell and CTL epitopes from tumour antigens over-expressed by cancer cells. .

"" Now keep yourself out of mischief""

who are you ?