Member Info for inanaco

learn something new

thought i would take a look at Graham Pockley .... he holds the patent for the Prostate Cancer Pap peptides ... and is in the Covid Group ...

what i did not know

Polynucleotides encoding the peptide, alone or fused to a polynucleotide vaccine as described above, may be administered, for example, intravenously or intramuscularly. Immunobody™-based vaccines have been previously found to persist at intramuscular injection sites for 90 days and lymph nodes for 7 days and induce strong CD8+ responses (Durrant et al Supra).

single vaccination can persist for 90 days ... ie keep the immune system on its toes

Anyway ......... Lets see how the Avidmab deals are structured, that will tell you if we have an Arm Holdings scenario starting to form, it's my considered opinion we have ... it seems the collaboration route leading to license deals is the right course for Scancell because our "Tech" within scancell is such high Quality, our greatest strength is we can develop in house, and the innovation is in house, with access to the University across the coffee table, and also we should thank CRUK for the initial support it gives to University funding of projects like immunobody ...

what Covid is showing you is the importance of Uk Innovators in a crisis ...... Scancell could be come strategic, indeed if Moditope hits expected efficacy, "FULL" development of should be done and if we follow the licensing route the dividends payable per year will dwarf the current SP ....

back to that "the number you hold"

rare chances like this occur ... a company with a Mcap of £80m with the potential to corner the market in late stage cancer treatments ........... look at the mouse data i showed yesterday !!

All kicks of in the New Year ....

Tick Tock

Crackin or UK shareholders not selling the "internet of everything" .......... cheap and failing to value it .. quick buck syndrome

SoftBank completes $31 billion acquisition of ARM - The Vergewww.theverge.com › softbank-arm-acquisition-complete
5 Sep 2016 - SoftBank surprised the technology world with a plan to acquire British chip designer ARM Holdings for £23.4 billion ($31.4 billion) back in July,

didn't .... acknowledge

Ivy come on is there any need for this ? because at the time every trade was made that was the market price .. !!!

you cannot be any smarter waiting because how would you know ? ............ its just a term bermuda used, he knows full well that nobody has that sort of insight ... indeed he has other holdings that have done far worse than Scancell

and scancell dangled the carrot few acknowledged what the RNS delivered

Avidmab and Homocitruline maybe some LTH that did acknowledge this substantial up lift in the IP and instead carried on with a relentless attacked of the BOD should look inwards first

Rats ... he had faith but greed to buy low consumed him

anybody buying now its the luck of the draw ...

however i have been telling folks "I am a Buyer" scancell is very cheap ...............in fact one man described us as

"ludicrously cheap"

even the most pessimistic ... kept a core holding just in case a deal .. popped up ..

different now Scancell seem happy to tell us they are close to concluding one

ask Knowlesi he is a shareholder

nobody in the last 5 years posted .......... """ I will wait until Covid arrives """

and they certainly did not buy in at the Lows

Redmile or Vulpes ..

wrong ivy ... those holding got preferentially prices at the OO

instant capital gain

exactly scousemark which is why many myself included did not sell and continued to buy through the perceived crisis that wasn't and i said the falling SP is your friend if you are buying ... what Ruck failed to see with GF and myself is our ability to divert cash as and when required because we are cash generators from other investments mainly property, and because we are experienced in property developments like Bio they can take many years to plan approve and fund. Thus sitting on non productive assets for us is usual ... but the End of the investment a completely different story .. i won't leave Bunsie out he also has access to funding at will, should the need arise because of his life experience of being an entrepreneur and still having the investment income flowing in ... There are some pretty smart people buying Scancell !!

explanation of Investing by Ruck ............. this will make you laugh

To Inan, From Ruck ....... 12 Sep '20

"Your last buy was 10p"

So what?

My 60,000 @10p will make more profit than your £500 @ 3.6p once the SP hits 12p
Or don't you think it will make 12p????

This is the trouble with your arguments - you put yourself in a position where you can't win on either of two binary options.

So SP over 12p, I've outsmarted your £500
SP under 12p, you've lost a lot of money.

So which of the losing options are you backing?

Oh, and at £8 per share, my investment at 10p will be worth £363,396 more than your 3.6p investment. Lol

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I believe his last top up was 5000 shares .. at 0p ... or 10p to correct the error ....

so basically he took the mick because i only had £500 spare at that moment ....

can any one do the maths on 5000 x 10p

RuckRover

Posted in: SCLP

Posts: 3,461

Price: 12.90

No Opinion

RE: AB12411 Sep 2020 19:54
Bunsie,
My average was 13.3 before I managed the extra 5000 at 0p. Not sure what my average is now as I haven’t calculated it. I have to ignore what Halifax says as it only counts purchases not sales.
Have a good weekend.

so Ruck take the mick out of £500 despite me near doubling my holding sub 8p

i actually filled my isa this year at the OO

255m Mcap

v

81m mcap ... with £15m cash and a huge pipeline ....

MaxCyte and its collaborators at the Johns Hopkins Kimmel Cancer Center explored the various attributes of MCY-M11 in nonclinical studies. In a murine ovarian cancer model, a single intra-peritoneal (IP) injection of MCY-M11 resulted in the dose-dependent inhibition of tumor growth and prolonged the overall survival (OS) of the mice in the study. Weekly IP (intra-peritoneal) injections of the optimized MCY-M11 dose boosted disease control and further prolonged OS, both of which improved with an increasing number of injections.

v

Results: The combination of citrullinated vimentin and enolase peptides (Modi-1) stimulated strong
CD4 T cell responses in mice. Responses resulted in a potent anti-tumor therapy against established
tumors and generated immunological memory which protected against tumor rechallenge. Depletion of
CD4, but not CD8 T cells, abrogated the primary anti-tumor response as well as the memory response
to tumor rechallenge. This was further reinforced by successful tumor regression being associated with
an increase in tumor-infiltrating CD4 T cells and a reduction in tumor-associated myeloid suppressor
cells. The anti-tumor response also relied on direct CD4 T cell recognition as only tumors expressing
MHC-II were rejected. A comparison of different Toll-like receptor (TLR)-stimulating adjuvants showed
that Modi-1 induced strong Th1 responses when combined with granulocyte-macrophage colonystimulating factor (GMCSF), TLR9/TLR4, TLR9, TLR3, TLR1/2 and TLR7 agonists. Direct linkage of
the TLR1/2 agonist to the peptides allowed the vaccine dose to be reduced by 10-fold to 100-fold without
loss of anti-tumor activity. Furthermore, a CD4 Th1 response to the citrullinated peptides was seen in
ovarian cancer patients.
Conclusions: Modi-1 citrullinated peptide vaccine induces potent CD4-mediated anti-tumor responses
in mouse models and a CD4 T cell repertoire is present in ovarian cancer patients to the citrullinated
peptides suggesting that Modi-1 could be an effective vaccine for ovarian cancer patients.

Thanks ... we are up and away .. i think the current re-rate has a way to go yet, and example of that was a quick flip between the mouse models .. of Ovarian which i did on the other BB did you read it ?

Times lines on something never done before ............

Oh well some still don't get it ...

100 years of science chasing cancer ....

time lines ?

well in tolerance

well Bermuda that IMHO is the image you have presented, however what ever it is .... I apologies if a miss understanding exists and lets move on ...

well that one statement has been proved to be completely wrong Ivy

"""BoD was not good in developing the science."""

and that is my point and what i have been saying for years ... that the science at this level is challenging indeed it took two years to understand how to build Modi1 stocks commercially as a conjugated hydrophobic peptides so even world leading manufactures struggled

imagine trying to copy it ............ end up like "son of Concorde" built by the Russians .. with wings added to try and make it fly ....... because they did not understand the concept

In fairness you had been quite negative towards the Scancell BOD .. Bermuda and rarely refuted, Ruck, Panama, Tosh, Lozan etc and never accepting that my posts are fundamentally correct or providing sufficient data to refute my claims even thou i dominated the posts with science backed Data. what i was referring to with fake news is often he situation when you post

"is this what you meant"

and what you was actually doing was Posting as if i had said that ....

then you speedy exits because the Challenging questions i can pose ...

Ruck has just done the same ........... I am filtered because he Cannot answer

exactly .......... example scancell targets 55% efficacy in the SCIB1 trials

Ruck targets the 45% failure .......... as a reason to call it risky ... even thou Scancell predicts we cannot help everyone

and my posts have already explained why

which is mainly around the cancers ability to "cloak" itself even hijacking the immune systems suppression side

so Nobody here can say i Have "Duped" ..... hence my anger about his ridiculous comment