Member Info for inanaco

VAL401: The main event is the completion of the Phase II trial with VAL401 in patients with late-stage lung cancer. The data confirmed the palliative effect and improvement of quality of life in the patients treated. VAL is currently in discussions with potential partners for starting a Phase III trial, expected next year.

sorry but it did not go into trial to test its quality of life ....

so i ask again from 7 patients what is the value attributed .. ?

can you confirm the separation from Risperidone is responsible . ?

what was the base line ... ie No Placebo was used

in what is written in RNS ..............

hence Don't moan at me

so what they have said

""" This part of the study is also further establishing potential efficacy levels """"

its aim was

o substantially raise the dosing level in patients in order to reach therapeutic levels and reduce disease progression

can you see how the RNS now ... is not reflecting what it set out to do ..

missing"""" therapeutic levels and reduce disease progression""""

bearing in mind the OCT 2018 RNS

The current cohort has already received the escalated dose. This marks the point that VAL201 entered the concluding stages of the Phase l/ll clinical trial.

so that 6 months of data !!!

as per RNS Dec 2017 ....... does escalation to achieve

·     To substantially raise the dosing level in patients in order to reach therapeutic levels and reduce disease progression;Â

have you seen any evidence yet of this ?

patient data ?

The Actual trial investigator reporting ?

Scans

ATB

Valju

discussing RNS .... not the merits of buy or sell

LOL

i suggest you look closer at the RNS ... as Val seems to have Two Phase two then ....

The completion of the trial is a mandatory milestone prior to permission being given for further pre-market authorisation efficacy studies (Phase II/III).

basically you are in a phase 1 ....... still trying to work out the dosage

and this part of the RNS on 201 tells you exactly ...

This part of the study is also further establishing """"potential efficacy levels"""""" and pharmacokinetic / pharmacodynamic profiles as well, providing supporting information with respect to the """"optimal therapeutic regimes"""""" to be tested in the subsequent late stage clinical trials.

in other words they still do not have a trial running yet that is at " optimal therapeutic" after all these years they still don't know what that is ..

Read the RNS .. Don't moan at me

now val 401 based on 7 patients gives you what exactly ?

next stage ...pretty well the same

https://clinicaltrials.gov/ct2/show/NCT01795703

what is worse .. Val will not get involved ... why ? if it's so good surely it would want to develop the asset.

after all its what VAL do ....

Whilst ValiRx currently holds a 55.5 per cent. majority equity ownership of ValiSeek, the Company does not have any further financial and contractual requirements or commitments towards the remaining stages of ValiSeek's clinical development.

have NOT been

The wish of Politicians rarely finds agreement with the voters ...

hence the Scot Nats or Sinn Féin have been able to consolidate a view on one particular area of policy

Don't read to much into Nicola's .. grandstanding

for future ref Rats .. it's called a Muktuk buttie ... but not available in Gregs

so why are you here with a Bazooka ?

Smart Move Crumbs ... in deed .. the Falklands .. you can have Real chocolate dipped penguins

Knowlesi Big Bazooka moment ... delayed as he buys Bonds in upcoming markets that are out of the current economic model like Venezuela "the Safe Haven for capitalists"

reads well ?

Further comparisons of the pharmacokinetic parameters of risperidone and 9-hydroxyrisperidone in plasma of patients administered VAL401 and the corresponding parameters obtained from published data for conventionally formulated risperidone provide evidence for altered biological processing of VAL401 as compared to risperidone

all its done is shown a "difference" between Risperidone and VAL401 and that its safe to use

so ?

i suggest you are caught up in Project fear ..

hate to say it but the Faroe Islands managed to stay out of the EU .. and survive ... an Island that clearly believes in itself

https://www.government.fo/en/foreign-relations/missions-of-the-faroe-islands-abroad/the-mission-of-the-faroes-to-the-european-union/the-faroe-islands-and-the-european-union/

7 patients ? and you are trying to establish accurate data to generate a deal ? all for helping you out guys but

the algorithm is pretty simple

n7 = worthless

based on what data ? quality of life .. ? 401 .. tap water is good for quality of life ..