RE: BA.2.75.2 variant17 Sep 2022 18:46
Aether, it is mutating constantly. Each new variant, or sub-variant, or sub-sub-variant, includes different mutations.
The ones that survive and spread the most are more transmissible, but transmissibility also depends on levels of immunity, which can come from prior infection or from vaccines. Immunity wanes over time. So - the 'fittest' variant this winter will be completely different from the 'fittest' one last winter - because of the context it's operating in.
It's really very important to get across that 'less severe over time' and 'pandemics get weaker and go away' are FALSE. This is received wisdom which has produced terrible policies that killed a lot of people. It is possible for it to get 'weaker', as it did in the first Omicron wave. It is also possible for it to get more severe and kill a lot more people, as it did in the Delta wave.
I
t is not going away.
We have to deal with reality.