Member Info for HelloSanDiego

Covid deaths are around twice the level of the same two-week period last year. New cases are much, much higher this year though. So, in a way, things are going better?

I get it now. As an inhalable, reducing breathlessness is likely to be one of SNG's strengths. So it would've been a considerable setback if they weren't actually measuring it.

pmjh - "I am delighted to see that Synairgen... will be taking in patients reporting breathlessness"

Thanks for clearing that up.

Ndn71 - "I’m saying we need to favour the symptomatic breathless to have the best chance of progressing from A2 to A3"

All the drug really needs to do is bring about some measurable improvement to progress. Why would breathlessness matter more than, say, hypoxia?

Ndn71 - "The outcome isn’t the issue, it’s the 'in-come'”

I don't understand. Are you saying there's some doubt about whether breathlessness is measured before patients begin using the drug?

Doesn't page 266 confirm that breathlessness is an outcome they're measuring in Activ-2 phases two and three?

https://fnih.org/sites/default/files/2021-10/ACTIV-2_v7.0-wLOA%20073021.pdf

SPRINTER and SNG001 phase3 are the same thing.
https://clinicaltrials.gov/ct2/show/NCT04732949

The other one we're waiting for is Activ-2 phase 2 and cmww2014 posted those details below.

I wouldn't really want to see the price jump up and down on rumours and hype. They're doing what they should be: focusing on the science rather than holding investors' hands.

Chesh - "With a 94.7p target price, means for a fantastic op don't dya fink HSD"

Not really. My lottery ticket could be worth £180m by tomorrow. But chances are it'll be worth f*** all.

drshan - "why do they turn up only when the price is dropping?"

Probably because the price has been dropping for a year now. But it's already dropped 50p so it might not go much further.

alkin - "but if any country did the math..."

It doesn't look like you have.

There are some serious logical flaws in your little rant there. Do you really think you know better than the world's leading statisticians and virologists?

Andym123,

You might not lose sleep over it, but you'll wake up and write a short essay trying to justify it to people you don't even know. Interesting compromise.

With the UK hosting COP for the first time since it began, I'll be surprised if the government doesn't take the chance to start making some noise about this company. They've recognised the potential it offers and have the ideal platform to position the UK and Velocys as industry leaders.

"Research indicates that by 2040 the SAF sector could generate between £0.7 billion and £1.66 billion a year for the UK economy, with potentially half of this coming from the export of intellectual property and the provision of engineering services."

https://www.gov.uk/government/publications/green-fuels-green-skies-gfgs-competition/green-fuels-green-skies-gfgs-competition-shortlisted-proposals

pmjh - "This isn't the reason I am ruling it out. How did you come to that conclusion? "

I didn't. I was replying to several people who have ruled out the UK gov's importance and the only reasons given all revolved around that.

I'm under the impression Synairgen is looking for support from the UK government in a variety of ways.

If you want to rule that out just because manufacturing is based outside the UK, that's fine. But it's not a very compelling arguement when the consider the whole host of ways in which the UK government could offer support.

pmjh - "If you think the UK Government are important to Synairgen, when it is obvious to most that the future of the company lies across the pond, then you're setting yourself up "

Richard Marsden's presentation on 30th September 2021, the slide clearly shows:

"Potential to increase capacity to ~100,000 treatment courses per month. Government support required to accomplish this larger scale of manufacturing operation"

You might argue that he's not referring to the UK government but I think you'd be clutching at straws. Here's the link: https://www.lsegissuerservices.com/spark/Synairgen/events/28f37f03-c7dd-4071-b047-66b191931742

"For the first time in the UK - and possibly the world - air pollution has been recognised as a cause of a person's death."

"The key in Ella's case was that a leading professional in his field, Prof Sir Stephen Holgate, was prepared to investigate all the evidence to find the link between a single death, and levels of pollutants in the air."

https://www.bbc.co.uk/news/science-environment-55352247

I can't see a tobacco company getting a look in here.

Woodstock1970 - "However I am wondering why the press is saying the flu this winter is becoming a problem with predictions of 60000 fatalities ."

You've misrepresented that report quite a lot.

The original research published by the Academy of Medical Sciences says "Between 15,000 and 60,000 people could die from influenza this winter according to new modelling for the report, though the planned widespread flu vaccination should help to reduce this risk."

https://acmedsci.ac.uk/more/news/winter-viruses-and-covid-19-could-push-nhs-to-breaking-point-warns-new-report

Retireby40 - "I’m not sure what details you’re alluding to?"

Ok, cool. Never mind.

Retireby40 - "HSD they will release material RNSs when they have to."

Of course they will. You're saying they'll release data only when they're obligated, and that's obviously true.

But if they have a product with such huge potential and they're confident in their ability to realize that potential, there's no good reason to keep the details from investors. So why do you think they are?

Retireby40

Do you have a better explanation why they're being so cagey about what's happening with it?

If it were going as well as we're led to believe, shouldn't they be going out of their way to publicize it?