Member Info for Grace83

Jenny, I wish!

Gin maybe ;)

Not you Jenny...that was directed at Baxters

Are you drunk?

Sorry, I always assume that everyone is intimately familiar with the results so far (as I am) and I can see why people can get very excited. I’m a typical scientist in that I’m always reserved and cautious, even when hopeful and excited about something...so will never get carried away. It must be so much more fun and I’m sure it would be better to be more excitable! Need to take a leaf out of others books...

Haha...it’s good to see you excited Baxters and enjoy your dinner.
I have to put in a caveat about these results though...we have one person with reduced psa so far. Increasing doubling time is positive, but the big one is reducing the psa level itself. We need more Of those from the increased dose, so it’s not a done deal To be the next xtandi yet. I can see why you’re excited to turn this around and I really don’t blame any of you guys that have been here a long time. This does seem like a completely different prospect now and Suzy seems to have a good plan for developing treatments early on and subsequently getting the funding to continue them, so it’s not on Valirx to carry out expensive further trials. So possibly more legs in this company for the future than I initially thought and I really hope that it’s successful. We will see what she comes up with and what irons are in the fire. 301 looks promising, as it’s not a far stretch from 201 at all, which would only need to be tweaked slightly for repurpose for endometriosis. I’m sure you already know all of this, so enjoy your evening.

I’m going to be up well before seven to check for an RNS...

It’s a bit ambiguous, so I would check with more knowledgeable people about the 16mg/kg mind.
Well we have results for the first eight people, so it would be a maximum of four, if they put all four people in the extended trial on to 8mg/kg. I’m not sure how they worked out the dosing until the results are out.

Hi Tommy
I’m not entirely sure, but my understanding is that they did approve up to 16, but 8 was found to be the optimum. George mentioned one adverse event, which I’m presuming was at 16, so maybe it was just too high? There should be some other people that know more on this, as I wasn’t around then and it’s just bits I’ve picked up...

Hunsen
Thank you for these figures. Your posts are always interesting and very well informed/researched. Might have a look at a few of their stocks now and it’s interesting to see that they have done so well here too this year.
When you look at it from that perspective, this stock has increased so much this year already. It’s easy to forget and lose sight of sometimes. I’m not concerned about RG selling in the slightest, as I don’t believe it’s anything sinister...just a bit of profit taking, which everyone is entitled to do. It has been holding the price back quite a bit, but more importantly, those sells have been absorbed easily and we are still making some progress. In fact, it’s a relief to know exactly what’s been holding this back recently, as it hasn’t made sense, with all of the positives lately. Lots of positive news happening and more to come.
Looking bright here :)

By the end of Q3 I believe, so end of September :)
GL

Viera, I agree with Valuefinder on that comment. That’s why I retracted my question, as my strategy is my own, as is yours, so I shouldn’t have asked you about your target. Apologies. We will all have to make the decision at some point and everybody on this board needs to do what is right for them.
Happily, we can all get on with being excited for the upcoming results at the moment :)

Actually, forget I asked. I’m happy here and will base any future decisions on the results coming soon.

And apologies oldbaldy, I’m sure you are very handsome. I just thought we were both on the same wavelength with the skittles comment :)

I’m pretty sure that oldbaldy isn’t your neighbour. He’s done a bit of googling, clever chap. I’ll let him explain.

Are you debating selling some before the results? I thought your target was at least 80p?

I agree with oldbaldy that you are who you say you are And Borgia isn’t correct

This bb is great. Some great people here, who are happy to take a bit of gentle ribbing. I think ST is great, but his new nickname cracked me up Jenny. When Mr N is constantly criticised, he just ignores it and does it even more, especially when someone mentioned about his posts not being up to date the other day. I wouldn’t even know about this company if it wasn’t for him

Yep. They clearly had a lot of money to be able to do this. We should have been at this stage years ago. Clearly nobody told George that you can recruit patients simultaneously and not have to study them one at a time! We find our optimum, which is 8mg/kg, by the looks of it, then extended our number of participants at that dosage to get to this. It shouldn’t take long, in a normal world that isn’t run by the old team.

I agree with oldbaldy. Oh and I swear I’m not this boring in real life oldbaldy!

Shai
I doubt you will have offended anyone. We are a friendly bunch and all need to learn about our investments. I’m still quite new here and there are quite a few things I have missed along the way :)

Oh I see! That’s awful! It’s hard to believe that people can be that callous...how they can sleep at night, I’ve no idea!

Viera
Congratulations on your realised profits :) You are one brave person and it’s great news that you managed to sell that many and we managed to absorb that easily and increase our sp by so much, last week :)
Ha...I think I should be asking you when to sell! I bought most of mine at 8-9p and haven’t sold a bean yet. It’s crossed my mind, but I decided to have faith and hold out for the 201 results before I even contemplate it. Putting my money firmly where my mouth is. Now hoping it’ll pay off, as I didn’t intend to put this much money in here originally.
Honestly don’t know what I’d do if I had as many shares as you though...

Oldbaldy
Yes, there are plenty of other amazing treatments in progress and I’m in quite a few pharmas and mining companies. This one really stood out to me because of the unfortunate position that we have ended up in due to the poor mismanagement previously, which has unfortunately stagnated the development of our potential drugs and driven the sp down to a ridiculously low level. This has clearly been completely unfair for the lth’s, who we all have a huge amount of sympathy for (Thankyou again, Freddie and Valju). So my thinking was and still is that this has the most potential upside in a relatively short space Of time, compared to others.
To answer you and Rscorpio, if I knew the answer to that, then I would have remortgaged and put the lot into Val. Unfortunately, we are still at a fairly early stage of investigation and whilst everything is looking positive, there is no way of knowing if this really does Reduce tumours until the results come out. I’m hopeful as the signs are there, but these types of things can never be a dead certainty, by any means. Src kinase inhibitors are now being found to have so many potential applications, that we should have been so much further into investigating their potential uses by now. Instead, George and Mildred took an inordinate amount of time and bled investors dry in the process, to get nowhere near where the company should have been at this point. Src kinase inhibitors are now being looked into to potentially treat neurodegenerative diseases (such as Alzheimer’s and ALS) and as antivirals, amongst the other areas they are already in use mentioned earlier, such as leukaemia treatments and cancer treatment in dogs. So what I’m basically saying is in the worse case scenario if this turned out to be ultimately unsuccessful down the line as a prostate cancer treatment, there’s a good chance of it being an effective treatment for something. We just need to find out what exactly and be in a position to move forward with that in the future. Sorry that I can’t commit more than that...I’ve topped up to increase my average a couple of times this week, so I’m with everyone else, in keeping my fingers crossed!

Tommy, we wouldn’t be able to partner with Keytruda, I don’t think, as they’re not effective against prostate cancer. Nice idea though and the idea of partnerships is certainly a possibility as with bc201, we need to use other drugs to help with the immune system response. We may well get a nice surprise there...who knows...along with 301 :)