Member Info for gixer

Out of stock at the moment but were we aware Fruitflow Plus was available here?
http://www.lloydspharmacy.com/en/fruitflow-omega-3-30-capsules

Not knowing the time scales involved in Blue Cap approval is frustrating as is not knowing what health claims have/are being applied for.
With any luck lowering Blood pressure is high on the list.

No idea what a pilot study like that would cost wellsite.

COMPOSITION FACILITATING LOWERING OF BLOOD PRESSURE AND DIETARY SUPPLEMENT

Publication Number
WO/2020/077747
Publication Date
23.04.2020

Applicants
BY-HEALTH CO., LTD.

"the water soluble tomato concentrate, folic acid, Vitamin B6, Vitamin B12 and Vitamin B2, and the combination of a plant extract composition and a vitamin composition achieves a synergy that enhances the effect of lowering blood pressure."

https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2020077747&_cid=P10-K9F8JJ-45635-1

https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2020077747&tab=FULLTEXT&_cid=P10-K9F8JJ-45635-1

Luke, over 100 regional consumer healthcare brands/products with fruitflow have been launched. However we dont know how many of those products didn't make it.
You will find the companies cash position in the interim results RNS.

Completed early despite what is happening in the world.
Study Completion:
June 2020 [Anticipated]
March 13, 2020 [Actual]
A Pilot Study to Investigate the Effect of Water-soluble Tomato Extract on TMAO
Locations
Ireland
Atlantia Food Clinical Trials
Cork, Ireland
Sponsors and Collaborators
DSM Nutritional Products, Inc.
https://clinicaltrials.gov/ct2/show/NCT04160481

There are 2 different agreements (not SPLITS) with By-Health.
1/ "The Company (PXS) has previously announced it was working with DSM and BY-HEALTH Co., Ltd (‘By-Health’), a
listed Chinese dietary supplement business valued at approximately £3bn, to support the planned launch of a
number of Fruitflow based products in the Chinese market."

Hopeful outcome, By-Health get Blue Cap and release products into the Chinese market after purchasing Fruitflow and/or Fruitflow products from DSM. Profit share between DSM and PXS.

2/ "In August 2019 the Company (PXS) was delighted to announce it had signed an open-ended collaboration agreement
with By-Health, in support of By-Health’s planned launch of Fruitflow based products in the Chinese market.
Project work will be managed and conducted by Provexis primarily in the UK, with the first project agreed
concentrating on the use of Fruitflow with nitrates in exercise, an area of considerable commercial interest to
By-Health. The agreement further strengthens the close relationship between By-Health and Provexis."

Hopeful outcome, By-Health pay PXS for project work carried out by Provexis. By-Health get Blue Cap and release products into the Chinese market after purchasing Fruitflow and/or Fruitflow products from DSM. Profit share between DSM and PXS.

That,s how I see it anyway and no mention of a 3 way split.
https://provexis.org/wp-content/uploads/2019/12/PXS_2019-11_Provexis_plc_30-Sep-19_interims_31-Dec-19.pdf

"Isn't Bi Health a 3 way split? DSm/Bi Heakth/Pxs"

Not that I am aware of.

https://m.facebook.com/story.php?story_fbid=10220961411920263&id=1090174970

From Puravida
Cardio Flow
https://www.puravida.com.br/natural/nutrientes/cardio-flow/

From Biogrow

https://biogrow.com.my/products/botanical-supplements/smoflo-capsule

Other than patent applications I am not sure what we can do with little cash.
"Intellectual property

Antihypertensive (blood pressure lowering) effects in collaboration with the University of Oslo, which have
now been granted for Fruitflow in Europe and three other major territories. Patent applications are being
progressed in a further five major territories to include the US and China, with potential patent protection
out to April 2033."

although there is some evidence that By-Health are/were doing a study
http://www.chictr.org.cn/showproj.aspx?proj=27048

General disclosure of price sensitive information
11. An AIM company must issue notification without delay of any new developments which
are not public knowledge which, if made public, would be likely to lead to a significant
movement in the price of its AIM securities. By way of example, this may include matters
concerning a change in:
7
— its financial condition;
— its sphere of activity;
— the performance of its business; or
— its expectation of its performance.

Much as it would be nice to get an update on China, no news is good news IMO.
https://www.londonstockexchange.com/companies-and-advisors/aim/publications/rules-regulations/aim-rules-for-companies-march-2018.pdf

trades shown on this site are from 13th Feb

CircuACE
https://www.youtube.com/watch?v=m40gZG9zwDE

Results:-
Fruitflow Inhibits Platelet Dense Granule Secretion In Vitro
Fruitflow Attenuates Platelet ?-Granule Secretion In Vitro
Fruitflow Attenuates Platelet Lysosome Secretion In Vitro
Fruitflow Has No Cytotoxicity To Platelets
Fruitflow Downregulates Platelet Src/PLC?2/PKC Signalling
Fruitflow Inhibits Platelet Granule Secretion Involving PKC Signalling

No idea what it all means but it sounds good lol

China
Fruitflow attenuates human platelet granule secretion through down-regulating Src/PLC?2/PKC signaling pathway

https://www.researchsquare.com/article/rs-17401/v1

2019 Annual Report : - Disclosure Date: March 13, 2020

6. Scientific research papers and reports The company attaches great importance to the writing and publishing of scientific and technological papers for employees, has formulated relevant incentive measures, and has made clear regulations on the writing, publishing and rewards of scientific and technological papers. In 2019, the company's employees published a total of 47 scientific research papers, which not only activated the company's academic atmosphere, but also significantly expanded its academic influence, as follows:

34 Water-soluble Tomato Concentrate (Fruitflow®) Toxicological Evaluation of Edible Safety Modern Health 2019/10

http://pg.jrj.com.cn/acc/CN_DISC/STOCK_TIME/2020/03/13/300146_nb_1207368915.PDF

Published in US end of February
http://www.freepatentsonline.com/y2020/0054706.html

Reason behind earlier post
https://www.youtube.com/watch?v=KtmTj__Xxe4
Video now in Malaysian and posted in Biogrow's youtube page.
https://www.youtube.com/channel/UCmvOZzmGRlV1f_UxwvrVg8g