Member Info for Gampy

Why does anyone care about this AGM so much.

A lot of us attended last year and we were lied to. All of us. When we held them all to account we got nothing but disrespect and weird looks from the BoD. We were sold down the river of multiple trials just to keep us quiet.

Here we are a year later after those lies and they managed to treat us all even worse than we'd ever imagined.

So I ask, why the rush for this AGM? Because what they proved last year was that they can lie to us and disrespect us and get away with it.

PMJH - I agree. However as Karley suggests, maybe the new entity of TFG as opposed to Polygon came with a speedier team at the helm (as I understand it, Polygon was created as a hedge within TFG with Griffiths involved in both). Perhaps rather than a 20 year timeline with this company, they've now been forced to work on that 5 year timeline.

Trials aside, TFG are surely aware of the going-concern/audit problem and the consequences of keeping the company on a right track (if not 'the' right track) in order to keep the company afloat, get a good trial going with a good probability of success, and therefore get this going-concern situation controlled. By doing all of this, the company remains afloat, they turn the tide in a matter of months, and they begin moving the valuation of this company in a positive direction.

They said it themselves - "sometimes we're involved in a business that's never gonna be bigger than 300-400 million". That was his worst-case scenario in that interview. What's Synairgen worth right now, 8 million? Is this not a reason they may have stepped in before that five year window actually ends, as the company seemed to be going backwards toward the end of their five year window rather than forwards? This is what I'm choosing to believe and I choose to believe it bodes well for us.

So in this interview I think he talks about giving one of these companies five years. In the first five years TFG are much more useful to the company, and once the company starts becoming successful then in the five years after that the company starts becoming more useful to TFG. That's what I learned from the video.

Are we not nearing the five years they'd given Synairgen? Five years and nothing to show for it save for a cataclysmic crash in SP. This isn't "volatility" like he says in the interview, it's a catastrophe.

Is this why they may have stepped in to get things going? Is this behind the exciting RNS we've just received?

"Referencing Gampy's silly bit of ramping was comical".

Doc.Daneeka, I beg your pardon?

But are we not being too hasty? They've apparently said an AGM will be coming with an update. The ONLY thing I've taken from their delay is that they have a reason for the delay, with said reason needing to be finalised and then included with the AGM update like they've said. They're now "excited" to start the trial.

If no AGM was forthcoming, they wouldn't have waited surely.

So in terms of going bust - it seems unlikely in my opinion based on the above. And in terms of shareholders being wiped out, TFG haven't intervened meaning they must be happy with the company's plan and the likelihood of them both taking things behind closed doors and de-listing etc just doesn't seem likely to me after 20 years of being a public company.

Doc, what would you constitute as going belly up?

Thanks Doc83.

So 15 months from the last AGM would make the AGM deadline for this year 29th September I think, so if the AGM's still held on or before that date then am I correct in thinking that no rules will have been breached?

Hm ok. So it looks like they do not clarify timing of IFN administration either. I think I'm just trying to get a grip on the key points of IFN use in severe infection because of the links between AZN's IL-33 work, and SNG, that keep being suggested here.

If I can understand how our drug, which could worsen inflammation in severe infection states like ARDS, would at all be linked with a BP who are trying to show that blocking that very 'worsening' would be the goal, then how can our drug be tied in with an IL-33 inhibitor if they both work in opposing ways.

Anti-IL 33 that would aim to improve an inflammatory state, vs our drug that could potentially worsen an inflammatory stage in SEVERE infection like ARDS.

Thanks DD.

There is something I do not understand still and I am rather feeling dismayed at my own knowledge of this all of a sudden.

Our drug wants a fire to put out meaning IFN has been shown to dampen inflammation and aid the immune response.

However, doesn't it worsen inflammation in the severe stage of infection like ARDS?

Ok.

So IL-33 stimulates the inflammatory response by way of ILC2s and cytokines which would worsen any ongoing severe infection like ARDS. Therefore a drug to BLOCK this would dampen the inflammatory response and aid recovery time. Hence AZ's IL-33 inhibitors.

HOWEVER. Our drug is used to AID the inflammatory response by providing more interferon before it gets to the cytokine storm stage as it's beneficial earlier but could exacerbate any cytokine storms in later stages.

Have I understood this all correctly?

Hi, thank you for this hard work!

Can I ask what the connection is between IL-33 signalling pathway paper that's going to be presented that AZ/Sanofi may be involved with, and Synairgen? What am I missing?

1.7, 2.8, 5.5?... How do you possibly know these specific numbers you need to buy in at/it could reach? I am not sure how the MMs do their thing but how do you figure any of that out?

Golly, that is quite the back-story to the character. If that is all true then I don't need to say anything more to the poster.

This forum is a nice place to be when productive dialogues are held and ideas can be exchanged. Paladin had a great post recently and good posts followed that one too. I choose to focus on those, as things can be learned, morale can be lifted, and people can be helped. But with posts like this one, nothing is achieved.

"All the best in any new adventures. Bye bye"

Posted by you in June.

Why are you still here?

Fruits; not usually but I'm away for the summer!

If the company was going private or de-listing then why announce to everyone an AGM will be called via an RNS. Straw-clutching admittedly here but if you're going to privatise/de-list then do away with the shenanigans and put us all out of our misery sooner rather than later - it would have benefited them to have done it months ago as they would have known they lacked funding for the P2 a lot sooner than FY results surely. The fact they're planning on an AGM implies to me they've got TFG on board with whatever plan they've put across to them who are happy to let this play out, and that instead of cutting ties with the PIs they'd want to bring something to us. I understand that this could all be the case anyway if the worst were to happen but this isn't screaming privatisation/de-listing to me.

Billywild, I don't think I will be attending the AGM unfortunately as it would be laborious for me to get to with flights etc. Besides if the company did not promise more communication last year then do the total opposite of that for an entire year to us all then I'd probably be more enthused about going. So I'm going to rely on ppl here attending and I await their minutes from the meeting.

TP; thank you for reporting back. The only thing I'll add to that is that the identical responses they keep sending out do sound more positive than negative to me.

I think you did read my post and agreed with everything I said, which is why you've addressed nothing I've said in it. You can't be bothered to read someone's post after you've accused them of two things that you've realised you may be very wrong about? There's your lesson in humility.

We're not talking about lacking funds to do the trials and what you said about that months ago. If that's what you said then pat on the back. But you've brought up "de-listing" more than once despite Synairgen mentioning an "associated financing plan with an appropriate level of risk and reward for Synairgen shareholders".

You might be right. Noone's attacking anyone, but if you say something on an internet forum don't be surprised if other people on it ask you to elaborate. I'm asking you politely to explain why you think the company is about to de-list.

This might be the fourth time I've asked you if you could explain why and you've failed again.

Manifesto.

You deserve your own thread after the ridiculously incorrect sagacity you've displayed on all fronts today.

I didn't join this forum before now due to the relentless immaturity and fighting on this forum that you yourself have been a part of regularly. I've joined the forum now, due to the words "de-listing" and "suspension" popping up here by only one poster, and as sure as eggs are eggs, it's you!

I am not sure how you've deduced that I have no humility from the posts that I've made my friend. I've neither started nor joined an argument, but merely responded to your accusation this morning that I am another poster. Easy to see why you'd pay such attention to posters and their post counts. If I spent my whole life on an internet forum and had 10,000+ posts I'd indubitably be paranoid too.

I have, more than once, asked other posters here if this joke of a company de-listing was even a possibility, and I did this because I do not know the answer. Frankly it worries me this is even being considered. I think it's very unlikely but I am not going to say it's not a remote possibility. Do you even know what humility means? That is humility my friend.

Now would you like to put your extra energy that you've woken up with today to good use and finally explain to us all why you think Synairgen are about to de-list or be suspended? Instead of saying the word "de-list" and not explaining why you think this?

The stage you so desperately crave is yours.

Manifesto has just called me Tommy which means he thinks I'm speaking positively of the company.

Let me be clear. I hate what this company have done to me. I'm down on my investment, the management are communicating hardly anything, I'm worried about when I'll get my hard earned capital back, and I think the board have been less than considerate to us all. I bought in when this was still on the way down and I'm stuck in here like everyone else now. I am NOT supportive of anything that this company have done to us investors. But I remain hopeful we all get to walk away from this happier than we are now.

That's how silly you've made yourself look today Manifesto.

And de-listing? Really??

Is anyone else here thinking delisting is a possibility even in the slightest for this company at this moment in time?

A company about to announce further details of P2 trial structure including finalising site locations, and an associated financing plan with an "appropriate level of risk and reward for Synairgen shareholders" (Synairgen's words, not mine).

Imho this isn't even worth considering. Anyone else have a different view?