RE: Enhanced Trial Structure16 Jul 2024 18:47
There most definitely are a number of non-dilutive funding options available; I've been saying it for months, as have others. Just a cursory read back through editions of 'Endponts' publications online will give you a a flavour for the array of funding options available. Mutually beneficial deals are not rare anymore, it's just some posters on here prefer to ignore them and not research them, as it does not serve their narrative.
Dipffs raises a very valid point about the trial structure in the recent report. Here's what the company said: "Preparatory work for a trial commenced in 2023 and has continued into 2024. The company is currently
finalising potential trial structures and a potential financing plan to enable it to pursue an enhanced trial structure. If this comes about, details will be communicated in due course.". For sure, the traditional clinical trial model is now longer an optimum route in this new age of precision medicine, which Synairgen are clearly aligned to. After all, the first dozen or so pages in their 2023 AGM report was pretty much just about precision medicine. Adaptive trials/platform trials / phenotyping - all words we are no aware of and link to enhanced trial design. Here is an article - worth a read - explaining how much cancer clinical trials are transforming from old P1,2,3 models, to using enhanced trial designs : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693060/
Finally, I think one would be misinformed to assume many investors have gone because they have lost faith and put any stock in some of the wilder claims made here. Based on what I know of a number of PI's, that is a false assumption with no basis in fact.