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Poisoned not prisoner. Predictive text rubbish
....or was he vaccinated? Conspiracy theorists - you decide.
....according to CNN. Quotes Fauci as saying more research required. Obviously lots of room for various treatment options supported by good data. Plus 55% of Americans expect the virus to get worse
Sparkle. They might be heading towards their twilight years but they clearly know the value of this and if the readout on COPD is anywhere near as good then there's even more value to be had. How much do they need? That's up to them but I'd look after my grandkids and great grandkids. Imagine being able to say" I'm lucky to have this great lifestyle because my great grandad was a scientific genius who helped saved hundreds of thousands of lives! And then because he got so much money he donated to lots of other medical causes. "
They've spent 15 years on COPD. I imagine they appreciate the support available to them for research on the development work they've done so wouldn't be surprised if they had philanthropic intentions if/when this goes huge
Sanofi bought Principia for $3.7b today and reported to have a $50b war chest for buyouts. SNG001 addresses a short term (next 2/3 years) worldwide need (covid) but also a long term worldwide need (COPD). This is worth far more than £1b. The likes of Venrock know this hence they're building a position and I'm sure so do Sanofi, Astra, Gilead etc. Some big stages to go through over the next few months with the expected news flows
"herd" not gets . Hate predictive text!
Fauci reported today as saying deaths occurring in trying to get to herd immunity will be too costly. You'd think he be very keen on a solution which anyone testing positive gets given a nebuliser which provides a natural protein to reduce, in most cases, the worst effects and side effects. Take some time to produce the doses but he only had to point to the costs of each ventilator, the loss of life. 'Mr President, we need to give everyone who has this virus this treatment and, along with everything else we're doing, we might achieve immunity by the end of 2021. But it's gonna cost billions'. POTUS -' we've already spent trillions so what's a few more billion. JFDI '. Fauci - 'Cheers boss. More good news is that this will help us to deal with COPD too'. POTUS: 'What the fck is that?'
Hey Everton.
Had it been the final would have been the best frame ever. Couldn't have scripted it. And normal to see them handshake at the end. Sanitised back stage and then possibly fined for bringing game into disrepute.
Talking of disrepute, Trump will ultimately be regarded as one of the biggest fools to hold power in history but if his scientists at the FDA approve SNG then we'll all see a significant increase in value. The science will prevail, he's just desperate and will pay the bill to save his political career. More fool the yanks if they vote him in again
Sparkle - agree that he's a complete fruitcake and twisted. However, do I want him to spend billions of dollars to help save lives in the US, get an economy moving, encourage the rest of the world that this is a way out of the unnatural world we've lived in for months and without it the next 12-18 months? You bet I do.
With the exception of Ardern in NZ, I don't think anyone has handled this pandemic well. Outside of Republican America most people think he's a rambling idiot (God knows how he's maintained his businesses) but if the yanks buy this so will everyone else. That's why RM is talking to the FDA. You don't have to like everyone in business but he'll pay top dollar for this so let him for once make the right call.....
And said he didn't care if the answer to the virus came from abroad, he just wants to get a result and save lives. Bit of electioneering involved but he'll pay anything to give the Americans hope and cling into power.
SNG001 could be his passport to power. That, or Joe Biden forgets there's been a virus
Trump just said that US working with other countries to find treatments and currently work being done to combine anti viral /anti inflammatory treatments alongside remdesivir. No names mentioned but would fit SNG001 profile - earlier stage treatment and developed by foreign but w ell trusted ally of the US. And RM referred to the FDA
Excellent post.
This has potentially significant value long term just to alleviate COPD because that population worldwide is also so big. Short term, it's the potential impact on COVID and restoring world economies where this is going to be so big in demand. Horrible circumstances for those that have suffered but is potentially creating the perfect storm for SYN and whoever they partner with. So I'd be surprised if it's not more than £7.50. I have no idea but a sensible share of global licensing rights paid for by all the governments desperate to reassure their voters and reopen economies pushes it further North than that - perhaps some patience through the winter
Sad thing here is that lots of suppliers have profited massively out of PPE (rushed and not up to standard),ventilators hiked up, hospitals popped up all over the world. Money was no object to get supply. I doubt any government was truly prepared for the scale of this pandemic. They need to be stockpiling across the UK, Europe, America's, Africa, Asia for the next 12 months. SNG might be the light at the end of the tunnel. If they're purchasing unproven vaccines they should also be stockpiling SNG, especially when/if the COPD trials produce positive results.support
Reckon Boris would commit to a couple of billion pounds worth of doses to treat UK sufferers. US five times our population, Europe another 4/5 times in the most affected areas, India and Africa even more multiples. The order book would be huge so needs huge production and distribution support. World wide licensing sounds like the way to go for me
Trump has signed an Executive Order to provide more economic relief for the US. They are well into trillions of dollars. Successful approval and then proven success in the field in an emergency use/live P3 trial and he'd happily pay billions to secure a 12-18 month supply of SGN. Plus, these big pharmas also have to account to their shareholders and pension funds whilst they're saving the world.
They've referred to making millions of doses. At the moment we have 700,0000 dead worldwide, nearly 20m infected. Of those that have recovered, an unknown number with lung problems, breathing issues, other organ problems. Cases increasing again and more likely as all governments try to revive their economies. This has the potential to save most of those lives in the 2nd wave,reduce the impact of side effects for the survivors, relieve the stress on the NHS and their incredible staff and provide a pathway to begin to reopen the economy properly. Price that. Get the WAY sorted
There is no way or at best a remote chance that any supplier could produce and deliver vaccinations for the world's population within the next 12 -18 months. therefore effective therapeutics are essential to both save lives and reduce consequential ill health. SNG001 hasn't featured much in the UK media but it's being reported in many other countries. We haven't heard much of treatments from other countries so this looks the most promising.
Chris Witty said he was 100% confident we'd develop treatments even if we don't get vaccines so I'd be surprised if he and Patrick Vallance and their teams aren't all over this
Just watched interview on CNN with 28 year old covid survivor who had to have double lung transplant and had other organs failing. Get EUA and Right to Try and you might have a chance of a few billion. SNG001 should be prescribed as soon as a positive test is confirmed.
His plan should be:
1. Get a test. If positive greatest centre will give you a prescription to get a nebulizer and a treatment from Synairgen which is very effective, uses naturally occurring proteins and prevents other damage to the rest of the body.
2. Take it for 7 days. Then get another test to see if virus cleared. If not another 7 day course.
3. Once cleared, invite 4 weeks after for antibody test. (for the ODD holders)
4. Resume life as normal
5. 6 months later invite for another antibody test to check levels of immunity retained.
Do this and you can see spread of disease, immunity levels, transmission levels and how close we are towards herd immunity. This is going to take at least 18 months to be effective but it would enable the economies of the world to open up. Several billion is a small price to pay for the health of everyone.
Most importantly which big pharma wouldn't want to be recognised as helping to save hundreds of thousands, if not millions ,of lives and the legacy that this could create. It took 3 years for the world to get rid of Spanish Flu a 100 years ago. We have better science but a much bigger population so this needs massive support to get us back to anything like we were. Gla
'intention to make millions of doses available '. BBC website states pandemic has cost travel industry £320b between Jan and May and now travel is being disrupted again. Add onto that hospitality and leisure. How on earth do you put a fair value on a treatment that will help 4 out of 5 to recover, with less side affects and, on the basis that the at home trial works anywhere near as well, protect the vulnerable in care homes? I have no idea but it sounds absolutely huge to me
....then again, it could have been something to do with Paddington Bear as that was the rucksack. So if there isn't an Ann don't blame the poor little bear