VIR & Glaxo11 Apr 2021 11:50
VIR & GSK are about to receive ‘emergency use authorisation’ for VIR7831, GSK have a 7/10% stake in VIR Biotechnology.
Dr Alexander Edwards, Associate Professor in Biomedical Technology, Reading School of Pharmacy, University of Reading, said:
The success of VIR-7831 is spectacular and this new medicine would complement vaccines and other new treatments to make major reductions to the terrible impact of COVID-19.
“This class of drug could be especially important for those people who are less protected by vaccines for example if their immune system is weakened (as recently discussed for some cancer patients) – we can supplement their own immunity with this “extra” antibody against the virus.
“One reason this is so exciting is that it may herald a “breakthrough” for this class of medicines – monoclonal antibody treatment of viral infection. Monoclonal antibody drugs provide ‘artificial immunity’ by manufacturing antibodies in a bioreactor.
In contrast vaccines trigger your body to make your own antibodies (and other immune responses). Monoclonal antibody drugs have been most widely used to treat cancer and autoimmunity, but have always had enormous potential to directly combat an infection.
If the headline 85% reduction in hospitalisation or death translates into widespread use, this will deliver on the great promise of monoclonal antibodies to treat infections