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Those 2 x 6.3m would add up to 4.52% of the total company voting rights. There are only three holders who are capable of selling that amount. Yorkshire Cancer Research, which I doubt, as that would defeat their presence and they are the biggest holders. Dawn Coverley who actually started the company and that would also make this a farce, and finally our new holders, which would be possible as they were given the stock for free, and it makes close to 50% of their current holding.

So the only deducement one can make is that we do have a potential buyer as the trades went through at ask full price, unless both 6.3m were seperate entities. I would also deduce that we should be then getting a new TR1 very soon, one way or the other.

mcadder as you may or may not know I have been in CIZ since 2019 in its various forms and still here. So no offence intended.

Fact 1 There has been no RNS to confirm any further sellers since the last RNSs
Fact 2 The only facts are the news coming out of the company.

You said "just imagine what would happen" and "you can imagine" and then said its not ramping its fact. Its not my friend its your imagination and your scenario "say for argument sake" has not actually happened. What is happening is the price is cheaper than last week and so therefore one will need to work out for themselves from their own risk tolerance whether that offers a good deal or not. Its a numbers game and the company has clearly put in the last China related RNS what those numbers could turn out as. That is why I personally hold, and not because so and so sold last week, or so and so bought or "just imagine." Imagination is very dangerous if not used wisely, and in these times imagination is the last thing we should rely on.

I will give you this much, its a good opportunity.

https://text.123docz.net/document/5952845-expression-of-ciz1b-in-patients-with-non-small-cell-lung-cancer.htm

Journal of military pharmaco-medicine n08-2018 disease status, suggesting that Ciz1b plays an important role in the development of lung cancer. The results also suggest that Ciz1b gene may be used as a biomarker for diagnosis and prognosis of lung cancer [5]. The study showed that Ciz1b levels help diagnose cancer patients with an accuracy threshold of 98% for patients with NSCLC and controls (AUC = 0.96). When comparing patients with NSCLC in stage I with asymptomatic smokers, or those with benign pulmonary lymph nodes, the AUC reached 0.913, and 0.905, respectively. In this study, we also analyzed the diagnostic potential of Ciz1b for patients with NSCLC and the results showed that Ciz1b was capable of detecting patients with NSCLC (AUC=0.602). Therefore, determining the presence of Ciz1b in the serum of high-risk groups is an effective non-invasive method for diagnosing, screening and predicting lung cancer. CONCLUSION Increased Ci1zb mRNA expression in patients with NSCLC was observed compared to healthy individuals. Citzb mRNA expression levels were associated with tumor cell differentiation and correlated with liver enzyme levels.

Ci1zb plays an important role in lung cancer development and has the potential as a biomarker for diagnosis and prognosis of lung cancer.

Ciz1b Variant as a Surrogate Marker in Surveillance of Lung Cancer Recurrence
https://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2016.193.1_MeetingAbstracts.A3129

'Conclusion: Serial plasma Ciz1b variant expression may have a tremendous potential to be used as a surrogate marker in surveillance of lung cancer recurrence, Ciz1b variant may serve as a unique noninvasive biological test for diagnosis and disease monitoring in lung cancer.'

2017 Apr

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441127/

Objectives
Non-invasive tests for early detection of lung cancer are an important unmet clinical need. CIZ1b plasma biomarker can discriminate stage 1 lung cancer from within high-risk groups with clinically useful accuracy, with ROC AUCs in excess of 0.9 for two independent retrospective cohorts, and could therefore meet this need.

Conclusions
Unexpected and unusual molecular structure of CIZ1b in native plasma has complicated immunoassay design, and delayed translation of this promising biomarker. However, CIZ1b can now be measured using a high-throughput, hospital-friendly sandwich ELISA format, overcoming an important barrier to further clinical development and application of this blood test for early stage lung cancer.

Before this gets lost in the minute by minute commentary, I am reposting this again.

This is probably one of the most important videos long term holders should watch. Posted on 11th Feb 2022 (10 days ago), and at last count only had 14 watches 10 as of last night). It will certainly rack up a lot more with time.

https://www.youtube.com/watch?v=MOswBpjrCQA&ab_channel=UoYCommercialisationTeam

https://www.youtube.com/watch?v=MOswBpjrCQA&ab_channel=UoYCommercialisationTeam

InvestingGenius

Could you post in what capacity the proposed directors are working with GW Pharmaceuticals as I am struggling on this? What are their current roles at GW Pharma?
I do not own any shares OCTP but its on my watch list.

Great news that they held and not sold. This will make the job of buying even harder for others as there is only 90m free float available (see post from em earlier in the week) and those have probably very few floating around. Given the next news as and when will rerate this. CIZ have confirmed to me they will update the website.

Jigger_1
Yes the information my friend is off the CIZ website, but the date was the first thing I looked for and realising it was out of date I used the various recent holding updates and today's total voting right RNS to update all calculations. I have made the amendments to the holdings so they are up to scratch to my knowledge and calculations. The Finance Yorkshire holding has been adjusted accordingly to take into account their recent sales. I have added Conduit's holding into the list as well.

BTW your recent posts have been very helpful. Nice one will use in my own researching.

Jim Nominees
46,590,287
16.73

Yorkshire Cancer Research
32,382,330
11.62

Finance Yorkshire Seedcorn Fund
7,437,410
2.67

Bank of New York Nominees
17,534,371
6.29

Roy Nominees
15,195,532
5.45

Dawn Coverley
13,359,042*
4.79

University of Sheffield
11,128,058
3.99

University of Leeds
11,128,058
3.99

University of York
8,195,045
2.94

Conduit Pharmaceuticals
25,000,000
8.98%

There are 278,447,788 shares (Total Voting Rights as of 16.02.2022)
67.36% is held by the holders above of which two are no longer significant holders, above 3%. Conduit Pharmaceuticals is the new name in the list. From the above list the total holding is 187,562,429.

32.64% or 90,885,358 are free float to the market right now.

PLEASE DO NOT PRINT OR CAVE INTO DEMAND FROM OTHERS TO PRINT YOUR HOLDINGS HERE. I WOULD NOT ASK ANYONE THEIR BANK PIN NUMBER OR YOUR CARDS AT THE TABLE. VARIOUS PARTIES HAVE MOTIVES. NEVER FORGET THAT ESPECIALLY THE NEWBIES AND THOSE WHO THINK THEY SHOULD DO IT AS ITS ONLY A BIT OF FUN. TAKE IT FROM SOMEONE WITH EXPERIENCE. DO NOT REVEAL YOUR HOLDINGS UNLESS ITS WITHIN THE LIST ABOVE.

Honestly Riseoftheporper? Short term above 4p. Long term, given that the deal of £300m per annum to CIZ cost free IF and that still an IF, is signed, that alone adds £1.08 to the bottom line per annum!.So long term I don't have a value as I will not need to ever sell this. This is if you were asking me my friend? Its a case of adding as and when you can which would be the better option.

Been here since the PSL days and been through the pain of the suspension etc like a few good people here. Now its finally paid off holding.

Sharebel its a guess if one does not research. There was no need for Nirland Limited to announce once they had gone uder 3%. They held 2,595,532 less than 3% announced 02.02.2022. On the same day a trade was announced after hours at 4.32pm for 2,595,532. It could be someone else, OR it could be them. The chances of someone selling externally the same exact number would be very coincidental. They are out but its not an issue given todays news.

Traders from 03 and 04 Feb are still settling up and the MM knows this and they are getting a fair price based on the buying then. Once cleared which will be by tomorrow evening, then I would think with confidence long term holders willing to hold for more than a year, will be adding once the herd have exited. The hangers on will also add and sell along the way and move on but with only 103m free float its going to get interesting this week.

No evidence of block seller. Last Seller announced they were under 3%. Next morning exactly to a share their 2.5m approx trade went through.

What is evidence and fact is traders are settling today and tomorrow on t trades done 7-8 days abo. Market knows it, intelligent buyers know it. Book needs cleaning up and once done, you are left with intense pressure upwards. To my estimation there is only 103m free float after significant holders are accounted for. Now you have 25m being added but not being sold.

So come end of the week it will be a personal shock if this is still sub 3p. Traders leaving from the same buy range 7-8 days ago today and being replaced by serious long term buyers. Stupid not to take advantage.

I have a theory but not facts. Going to see how events play out into next week and then I reply to you. Going to do a bit of number crunching over the weekend first as I could be totally down the wrong alley.

Thanks for the reply. I certainly don't think his 3.9m would make much of a difference and to be honest I have had a personal meeting with him 3 years ago which was interesting helpful and eye opening. He came across as someone dedicated to seeing BOU succeed so your guess was a little confusing.

Widglide, honestly feel for you being 90% down. I have been there and in a flash it turned into multiple profits, but had to go through 4 years of hell first. Hope this link helps. We are shareholders supporting a business, which sometimes comes into conflict. Maybe this link helps explain better?

https://www.ft.com/content/0b4be1bc-1790-49bc-b5c6-bfff2e52e02b

widglide, I am sure there used to be a poster by the name of wideglide who used to post here ages ago? Very positive before it was suspended, whereas in respect to you its the opposite but I do respect your stance.

Can I ask what proof have you that Antos has sold please? "Antos walked away extremely happy and made a huge profit" As far as I can recall his holding dropped to around 1.5% or 3.9m (previous hold was 1.96bn before 500-1 consolidation). Since 5m was sold in one hit yesterday and the price hardly flinched today, what difference does his 'selling' or presence make to you? You mentioned it so I am curious. Thanks.

Just for the record:
Debuted on 09.02.2021, with the market cap of around £32.8m, and had 2.229bn shares at 1.475p.

Current market cap is based today’s price of about 1.8p and with 2.682bn shares around £47.7m.

During the year it recorded a high of 9.25p, which at one point shot the market cap to around £206m.

The shares are mostly driven by retail investors, who have a tendency to hold short term, and there has been no real record of significant holders. Therefore the price action reflects exactly what you would expect from a retail driven stock. Its volatile! Its slow torture! Its predicted to never recover!

As results are due soon, that could all change, and recently the trading has shown signs that the stock has been accumulated (see Mid Dec to Mid Jan) and that retail are being driven to the edge of desperation. A few said you cannot gain any evidence that charts tell anything. It certainly cannot predict price movement going forward, but what it can evidently show is the pattern of price behaviour, which right now is going lower. It’s being driven lower because retail sell in droves more than long term buyers accumulate. The fact that is has been nothing but a straight line down for six months is more evidence that this has been retail to blame.

Initial market cap of £32.8m V current £47.7m with results on the way? Retail are again making the classic continuous mistakes. No proof results will be good or bad right but right now retail are in the driving seat and they are driving it over the edge of a cliff and convincing themselves it’s all bad.

Capital raised, contracts signed though incestuous in some cases, and in an industry likely to explode upwards, it’s going to be interesting.

NOTE to retail: Biggest ever mistake. Invested in VMP in 2010, price kept dropping for 4 years, invested all the way from 3p down to 0.04p! held 5m or 1% of the company, losses were life changing, the negativity immense, the calls to get out from others rising each day. Robbers! Thiefs! Roll on 2014 just wanted my money back, sold for £30000 when it bagged multiples, and walked away with profits. Thank God I was out. Roll on 2022 VMP is REAT and my holding would have been £175000! Now who is laughing?

You can ilsten to soothsayers the ones who don’t research properly, they are your best friends and they will keep you poor and convince you from the 10 minutes they have held to get out while you can.

Thank you Magoo and hopefully you will not have to wait 2 years my friend. Confident this will come to fruitation very soon.

Jones2810 excellent thanks for posting the reply from Peter, appreciated. He has not broken any rules, as I can confirm that BOU had a PR team acting on behalf of Dr Allan Syms., chairman. This was to stop all the insulting, panic riddled emails that he kept getting. If you come across professionally and friendly you get help. Example of one of the replies I received was:

"Let’s hope so and hopefully the next email you get from me will be attaching an announcement, which with a fair wind looks like next week now." That was March 2021. Bould returned as Cizzle on May 2021. 13 months after cancellation on AIM. People can think I made that up, fair enough, but I am withholding my name and the PR MD's name, for security purposes.

I should have also added that during that suspension period the level of secrecy, confidentiality and abiding by the rules by Bould and those associated (PR marketing) was second to none. It was handled in hindsight very well with no leaks to destroy the deal. You get the same here with SPC. The posters who are impatient remind me of similar at BOU. They have all disappeared since and the same will happen here. Yes it was frustrating but some of those who are getting personal are doing it because of their own behaviour and characteristic patterns. They are not helping the cause. Patience is waiting over 2 years and now having the investment back. On the face of it I do not believe SPC will be the same. It will complete. Good on Jay and co for not revealing what they cannot and destroy the deal.