RE: Sareum get a mention.21 Jan 2020 09:27
Sareum also think inclusion in the Immuno-oncology article is good as they have tweeted the article this morning:
https://twitter.com/Sareumplc/status/1219547897425027072
Relevant part:
'Cytokines
Cytokines are a bit more complex to explain. In simple terms, they are a group of proteins that play an important part in boosting the immune system.
They have a lot of control over the body’s response to an antigen – a toxin or foreign substance which causes the immune system to start making antibodies.
If there is an imbalance or their production is altered, this can lead to tumours developing.
Scientists have developed man-made versions of interferon and interleukin, which are types of cytokines found in the body.
On the flip side, if the body is producing too many cytokines, Janus Kinase (JAK) inhibitors can stop the proteins from being excessively activated. These have proved useful in treating cancers like renal cell carcinoma and melanoma.
Sareum Holdings PLC (LON:SAR) is among those developing TYK2/JAK1 inhibitors. In fact, it has two of them, SDC-1801 and SDC-1802.
Preclinical programmes have been mapped out for each discovery with the aim of getting them into the clinic in 2020.'