Member Info for CHELSEA7

Will take 150k at 7.22

Buys 265k

Sells 106k..........................6 trades..................3 buys............3 sells

A nice 105k Black Trade (Buy imho) at 7.50

Kost his fight against cancer today, after a long battle where he fought so hard, topped the most recommended posterlist for many years and spent his final year in hospital as he said here losing his battle, and commiserations to all who new him an who was never into Biotechs, but he enjoyed posting here in recent weeks. and stated he was onthe look out for news here to ease his sufering. Commiseration to his family and Wassatt r,i,p fella, you gave every thing to thrsr BBs for a very long time.
Catch you guys tomorrow.

Just seen the news about Wassatt, a brave man to the end and when he said he was in hospital struggling we all kinda knew what was coming. He will be sadly missed by so many, he was a genuine chap and loved to do what he did best on these BBs with myrth. My deep condolences to his family, another hand picked for heaven, heaven is a richer place for him. R,I,P Wassatt you fought the fight of your life, ATVB Chelsea7x

Just a little one, closing SP 7.2/7.8, just the two trades, 100k and 63k buys, NO sells more importantly, and the MMs close taking 150k shares at 7,33, started the day at 7.07.

Just thinking about the Fibonacci Retracement articles from last night, and the 50% figure was introduced after the original levels, which is interesting as at the high we were 150% up from the 3.7 level, and at todays close 7.50 we are a smidge over 100% up, which means we have retraced 50%!! Phew thats a mouthful. Never given much time to TA, probably because I have never studied it, still feel it is a self fulfilling chart, but very open minded to it.

Night guys, self fulfilling or not, it has got me interested, and that is only a good thing.

Guess so. The mathematical modelling for trading came after that

Would you believe, just the two trades still, a 100k and a 63k buy. Hope I"M not tempting fate but will happily take that at the close.

Inan, did you mean to post that link?? Check it

Yeah was reading that last night, very interesting, haven"t finished with it yet. Back to shares, doing a bit of jiggerey pokey, I managed to work out the first Fibonacci Retracement point as being the 23.6%. Admittedly I am perhaps bias, but can you see how that works out?

Will still take 150k at 7.33, that is the first time in more than a week that the bid has gone up so much from the open, time for a change in sentiment??

The Western Front...........still just those two trades, a 100k buy and a 63k buy over on NEX. Last time i looked a dummy sell was for 150k at 7.33, up from 70k for 7.07 at the open. Been very hard reading Level 2 lately, hoping it suggests orders to be filled and a respite from those 50k and 100k sells.

Thanks Ray. So many of these links make more sense now than they ever did to me especially with reference to combination therapies where they explain exactly what does what, and lets face it it is pretty much updated from 3 years ago. This part is to me so interesting, and it makes understanding what Scancell are doing that much easier, and note by easier I don"t mean simpler, it doesn"t come easy for me, never has, but by researching what is relevant to us certainly helps, and that is why i appreciated the posts yesterday, it pointed me in a few directions that I wouldn"t have thought of. Surely that is what a BB should be used for? This piece, for example, is what I find interesting.........................

Combination therapy using both anti-PD1 along with anti-CTLA4 therapeutics have emerged as important tumor treatments within the field of checkpoint inhibition.

A combination of PD1 and CTLA4 antibodies has been shown to be more effective than either antibody alone in the treatment of a variety of cancers. The effects of the two antibodies do not appear to be redundant.[5][31][32][33] Anti-CTLA4 treatment leads to an enhanced antigen specific T cell dependent immune reaction while anti-PD-1 appears to reactivate CD8+ T cells ability to lyse cancer cells.[5][34][35]

In clinical trials, combination therapy has been shown to be effective in reducing tumor size in patients that are unresponsive to single co-inhibitory blockade, despite increasing levels of toxicity due to anti-CTLA4 treatment.[36] A combination of PD1 and CTLA4 induced up to a ten-fold higher number of CD8+ T cells that are actively infiltrating the tumor tissue.[34] The authors hypothesized that the higher levels of CD8+ T cell infiltration was due to anti-CTLA-4 inhibited the conversion of CD4 T cells to T regulator cells and further reduced T regulatory suppression with anti-PD-1. This combination promoted a more robust inflammatory response to the tumor that reduced the size of the cancer. Most recently, the FDA has approved a combination therapy with both anti-CTLA4 (ipilimumab) and anti-PD1 (nivolumab) in October 2015.[37]

Seems like only yesterday that combination got Approval, but it is nearly three years ago now. So much has changed in that timeframe.

I trust your post was in reply to one of my filtered posters. FWIW I read your post that way, and that post got me researching in the wee hours. FWIW as i said earlier, thanks to you, Wildforce and Ray for some very informative posts yesterday, all of them got me thinking, even down to a reminder that Keytruda works on the T-Cells not the cancer, just the small things..........

Action on the bid............MMs began 70k at 7.07 moving to 7.23 for 70k..................now will take 150k at 7.33!!!

Is it possible our seller has finished for now?? Just two trades, 2 buys...........100k and 63k

Buys 163k

Sells .......

100k buy here at 5,575 and a 63k buy over on NEX at 7.5, hence tick up,

Will take 70k (not very accurate) at 7.23. Started the day 70k at 7.07

7.20/7.80

Fibonicci Retrace Support?? Hmm, hope so.

7/7.8

Nice start a buy at 7.575

Hopefully support will come in now.

Yes they are.