Member Info for CHELSEA7

Tee Hee, well at least CH hasn"t used that word for a while, and he has earned a lot of respect from me for what I presume is his excellent work with the three collaborations on the Third Platform, amongst with what I can only presume are many other issues too.

I"ve got some really good news regarding my scans last Monday which were the first ones I have had since June last year after the Cryoblation operation, and after going to the Radiographer for a Stewards Enquiry, it has come back ""clear". The first time in seven years I have been clear for so long. The rest of me,....well no need to go there, but i have booked to go to Naples in November for just under a week with friends, not quite the world cruise I once had my eyes on, but the first time I have been away for nigh on ten years.

So come on Scancell, you have a timeline from me, lets get our patients treated and get those collaborations over the line, by end of this year

As for us. we know what we are waiting for, careful what you wish for springs to mind, but lets get an update, filled with hope , I think we all deserve that.

I just wonder how long ""shortly"" is in Biotech terms, lol, well we should find out in the update with the Interims.

Good to see Lindy getting the Market to receive MOD1 warmly, and I just wonder how long we will have to wait for our fourth collaboration?? It feels like that could be anytime soon, and it is certainly supporting the SP as we wait on so many items of news, the rises are getting more, the retraces smaller, and remember momentum was driven by the Vulpes Holding RNS on the third platform on collaboration two, and the third collaboration we saw the 8p breached, and a record in recent times with 60 trades in a`day. So that is collaborations in Sept, December and January, the next one, the fourth may not be far away at all.

Till tomorrow guys, still fair to say news will come this week with the Interims/Updates, even next Monday at a push a day before the February 4th Conference. A reasonable bet too that news of a Fourth Collaboration could come at any stage, each one validating the potential of the previous one, not just for us PIs but for the Industries information too

Just update on AIM share chat.and delighted to see three likes on the main post and another on the second smaller one, not bad, it was only posted a couple of hours ago and thanks to those here who are supporting it. One thing I promise is many more PIS are aware of our potential than they were just a couple of months back, lets keep it going.

Nice one cc, that is two conferences you have uncovered in the last couple of days, to add to the Feb 4th one, just a clip.........

FEATURED PRESENTATION: Stress-Induced Post-Translational Modifications (siPTMs) as Targets for Cancer Vaccines


Lindy Durrant, Ph.D., Professor of Cancer Immunotherapy, University of Nottingham; CSO, Scancell Ltd.

Citrullination is a widely expressed, novel, stress-induced post-translational modification that is a potent target for cancer vaccines. There is a repertoire of cytotoxic CD4 T cells in mice and humans that recognizes citrullinated epitopes. Tumors over-express PAD enzymes. Inflammation and stress induce high levels of autophagy and MHC-II presentation of citrullinated epitopes on tumors. Citrullinated peptides demonstrate potent anti-tumor immunity with no associated toxicity and will shortly enter the clinic.

So, "" Citrullinated peptides demonstrate potent anti-tumor immunity with no associated toxicity and will shortly enter the clinic."", we can almost feel Moditope coming

7/8

-3.23%

And just one sell 4,602 since the MMs pulled the bid to 7p................phew!!

Night guys

Now taking up to 150k at 7.02

At 7.31

And we Tick Down to 7/8

MMs 5 v 5, would be no surprise to me to see Peel or CFEP pull the ask

https://metro.co.uk/2019/12/27/cancer-patients-given-fitness-training-options-to-boost-survival-rates-11963924/

I first heard of this three years ago when my best friend was diagnosed with Bladder Cancer. He was privately insured and had chemotherapy for a few months before surgery. Fortunately the chemo stopped the cancer spreading any further and with surgery they were able to replace the bladder with a plastic one and he is all clear now.

Just prior to chemo he was advised to do exactly what the link is about, at a cost of £1000, privately, and as a result his body was much stronger to deal with the side effects of chemo and surgery. Remember, many patients are too ill with other conditions too, or just plainly unfit and they are precluded from surgery, which saved his life.

Great to see the NHS taking these steps, every little helps.

Buys 36k

Sells 182k

27/01/2020 10:02 10,000 7.7......................Over on NEX, and 26k here also at 7.7

At 7.47.

So a Tick Down to 7.30/8,

Thanks inan, yeah that was my question................""Now we have a man who can do what the specialists find so hard to do?? Forgive me for being a bit synical but how do his cancers grow so large and metastasise before his white blood cells kick in???""

That is a subject I have discussed with my own oncologist too many times to remember in the last 7/8 years. I have actually seen a couple of patient files, anonymous of course, showing the mutations that occur. No wonder with all the amazing technology they have at their disposal, that seems to be the biggest stumbling block of all. Thanks for replying.

That was first reported the 6th March 2015.

I would reckon there is enough instances of self curing cancer to fill many volumes, in the meantime all treatments focus on urging the bodies immune systen to fight cancer that these people seem to be able to do without treatment. Programming T_Cells................hmm

A Sell.........................

27/01/2020 08:09 108,042 7.55

MMs not taking that many at about 7.5625

The Daily Mail are certainly building up to World Cancer Day with a string of cancer articles.

Now we have a man who can do what the specialists find so hard to do?? Forgive me for being a bit synical but how do his cancers grow so large and metastasise before his white blood cells kick in??? Certainly seems real enough, an extraordinary man.

Yep, second trade a 10k sell at 7.60.........................showing in triplicate.

Thank the Lord for that, thought it was me!!!

Morning, first trade 9.990 sell at 7.60.................I believe it is showing in triplicate, three transactions executed at the same time?? and last week we saw the first 5 trades showing in duplicate.

MMs taking 100k at 7.6 and after the sell 110/130k at 7.525

ISA Pharmaceuticals too. Still going through it, I had no idea this conference was going on.

Wow that is some list. Appears we are presenting on Day 1 at 16.45, but boy that PDF is 36 pages!!!

Thanks cc, great find.

And I wonder too whether we might just get some news regarding BioNTech, just something one day from our flirtation with The Karolinska Institute, perhaps even some news regarding any potential funding for Moditope.

In each of the last couple of years a few of us have observed that the plans the BOD have made have suggested that they know pretty much where and when the next raising will be, I can only assume they know exactly when the next will be, and IMHO that could well be in late October when the accounts are signed off. That was something I was discussing with David Evans, and David presuming you are reading this BB which we know you do, would really like you to comment on when you can on ADVFN. It is my hope that would assist many of us into not jumping into any unrealistic conclusions. I hope to David you can see your way through any issues that are preventing you from posting here on LSE, health and time permitting. Sending you my best wishes too.

So it is an important week ahead for us all, as we all wait to hear some direction as to existing plans, and alleviate uncertainty that exists in any of us. It does seem to point to an RNS this week, for the interims, update and news, and who knows if that is correct it might be well worth setting your alarms for 06.55 in the morning.

Have a good evening guys, lets hope for great news, Moditope feels close enough to touch. ATVB

Yes, Good Morning,

Pretty sure that is what we all hope for, need to happen, and allow us to focus on the here and now.

I believe after eight years here, I understand why to a large extent news takes time to filter through, although that is very frustrating for most of us.

Personally my hopes are that the IND has been reubmitted to the IND, but as Ray Pointer pointed out we were not RNSed the first time we submitted it, so the chances are we will suddenly be notified it has been Approved or not. Further that the MOD1 we trial is as close to the timelines set as possible, delays to the trials have damaged us so much, and lets remeber SCIB2. How well that will go down to hear the trial is being initiated by CRUK.

A fourth collaboration will surprise none of us, and as Ivy posted we will be able to make better informed decisions about our investment.

So lets hope for some good news, I will remain hopeful and positive until the fat lady sings.

Have a good day all.