RE: SCLP...how valuable!3 Nov 2020 18:49
Agree with Redmile firing on all cylinders, as I posted below Martin Diggle sold just under 2m back in April at 8p. I don"t think Scancell or here knew of Redmiles interest then, relevance being we hear these deals take money months to finalise and whether it is a lot of money to them, or not, it is a lot of money, certainly to us. In the months after we were awarded the INNOVATE funding for £2.9m and appointed manufactures for the vaccine. I think many of us would love to know when the cancer trials will re open, but reading this from the October 2nd RNS reminds me of the high hopes we and others have for COVIDITY, even more valuable as developments now think antibodies created by the treatments of Big Pharma have a shelf life of only 4 months, dereasing quickly in the over 60 age group. To remind...................
2 October 2020
""Cobra Biologics selected to manufacture plasmids for Phase I clinical trial of Scancell's COVID-19 vaccine in 2021
The collaboration will ensure GMP production of material for the Phase 1 clinical trial of Scancell's DNA vaccine against SARS-CoV-2
Oxford and Keele, UK, 2 October 2020. Cobra Biologics (Cobra), part of the Cognate BioServices family, an international CDMO manufacturer of biological materials and pharmaceuticals, and Scancell Holdings plc (Scancell), the developer of novel immunotherapies for the treatment of cancer and infectious disease, today announced that they have entered into a collaboration for Cobra to manufacture Scancell's COVID-19 vaccine. The agreement covers Good Manufacturing Pracatice (GMP) production of plasmid DNA needed to generate the DNA vaccine, against SARS-CoV-2, for use in a Phase 1 clinical trial in 2021 (COVIDITY). The project is funded by an Innovate UK grant awarded to the consortium between Scancell, the University of Nottingham and Trent University, as previously announced in August 2020.
Scancell's DNA vaccine will target the SARS-CoV-2 nucleocapsid (N) protein plus the key receptor binding domain of the spike (S) protein to generate both T cell responses and virus neutralising antibodies against the SARS-CoV-2 virus. This new vaccine has the potential to provide long lasting immunity against COVID-19 by generating protection not only against this strain, but also against new strains of coronavirus that may arise in the future.""
The interest from UK Government seems IMHO to have increased Redmiles interest after the 2.9m funding and I asked earlier what value might be attached to our vaccine. A very speculative question,but the more I dig, the more I think COVIDITY is one of the drivers behind their interest and news flow could well drive this past the 20p you mention. Then we have the result of the adjournment quickly followed by the AGM where we expected to hear news on many issues which will hopefully see us back into cancer trials end H1 2021. I think the importance to us of COVIDITY has been understated but could well be driving