Member Info for CauldStream7

Hi Dallo,

You have messaged on this board, in Sept 2024, that you hold 5 million IMM shares and have been an investor in this company for over 10 years. Very impressive. Are you going to hold on to your shareholding or even increase it given that the prospects for its share price look much better? Or cash in some of your chips? There are quite a few of us in the same boat.

There's a good feel about that really BIG buy @ £ 9000. And the Board is bound to ache for a good news story on the anniversary of the Simbec-Orion appointment.

Tonnacombe,

I agree with your observation that the appointment of the new CFO is a positive sign. There can be few people, and certainly no one on this bb, who knows anything approaching as much about the financial prospects of IMM as the new CFO. That being so, would she undertake her new role unless she felt the optimistic about her future job security?

Of course, we still need information about the IMM drugs pipeline, lots of it, particularly about the P140/Lupuzor phase 3 trial.

What do all these tiny transactions mean? Any why are there so many "unknowns"?

I doubt if anyone contributing to this bb has much of a clue about the future of Lupuzor.

I still believe that the Lupuzor Phase 3 Trial will go ahead and will be successful. My belief is based on the continuation of the Collaboration between IMM and Dr Syliane Muller the scientist who discovered theP140 peptide (Lupuzor) and of CNRS, the top French research institute where Dr Muller was the leading research pharmacist. The continuing collaboration of these two, reassures me that they have too much invested of their reputations to allow P140 to fail.

They know so much more than we do about P140. If they are still supporting IMM, I feel reassured that all will be well in the end.

Wigwammer:

Thanks for your thoughts on IMM.

Wigwammer,

First, I must apologise for writing "last September" instead of last December in my last post.

Second, I commend you on accepting your responsibility for your decisions to buy and hold Immupharma shares. As it happens, so do I but I also depend on the newsflow (or lack of it) from the Company for guiding my decisions.

I do not think it is incompatible for TM to be endeavouring to achieve the best result for Lupuzor as soon as possible, with providing more transparency and more regular information shareholders.

Wigwammer

With respect, an undertaking was made in the RNS of last September, to provide detailed information on the progress of the trial at regular intervals. I took that to mean quarterly, or at a minimum, half-yearly intervals. It is the absence of these regular reports that I find annoying and a feeling that I've been taken for a ride.

Exactly 11 months ago, IMM posted a RNS to inform shareholders that Simbec-Orion had been appointed as CRO to undertake a Phase 3 trial on Lupuzor.

In the course of that upbeat RNS came this sentence.

"As the study moves forward in 2024 , further details on the study's timings, protocol and key elements of the clinical trial design will be communicated at regular intervals".

Perhaps I have been asleep, but I cannot recall any communications from the company giving shareholders details of the progress the study/Phase 3 trial. Is this forgetfulness, lack of any progress or what?

I remain of the view that the directors of IMM are not being deceitful and that refinement of the basic trial parameters, recruitment of patient volunteers, etc is still going on. But we were promised this information at regular intervals and it should have been supplied.

Wildbunch: I totally agree with you. It won't be long before we are proved right... or wrong.

There seems to be a presumption that the Company should have issued a RNS at 7 am. But consider that on 3rd June, AT 10:09, Imm issued a RNS "Realisation of c £1.5 million on sale of shares in Incanthera". Moreover, since then it has issued all 4 of its RNS announcements in the afternoon. So, don't despair..

Wildbunch:

The board of IMM is being remarkably tight-lipped. I find it interesting that your request for an RNS which would update shareholders was not met with even a vague promise of one. Obviously, that would be the case if some very big announcement was imminent; the Board would not want to divulgeit prematurely until all the i's were dotted, etc.

Will it be good news or bad.? I favour the former, bearing in mind the upbeat mood of the AGM and your decision to purchase 200,000 shares immediately after the AGM, an increase of over 10% in your shareholding. Could the mood music of the AGM have misled you?

On the basis of believing that you were not a sucker, I think there is likely to be a big announcement that will have a

substantial impact on the share price, on the upside as they say nowadays.

To all well wishers.

Thanks to all of you for your good wishes. I find it very reassuring that so many of you are very supportive of the science behind IMM's P140 peptide platform for the similar reasons to myself, because we see in it a possible cure to a number of autoimmune diseases that affect family members and friends with often devastating effects on their health.

It may explain why so many of us continue to hold these shares despite being told that we are investing in a lost cause.

It seems to those investors who have invested in IMM as just another small and risky pharma that the only rational step to take was to divest oneself of these shares in 2016 when Lupuzor failed its first P3 trial and that we have been pig-headed in persisting in holding on to our belief that eventually Lupuzor will succeed in a future trial.

8 years later we are still waiting and still believers. Will we be proved right, hopefully some day soon?

Best wishes.

Thanks Nolupus for your good wishes despite our differing views from time to time. It's good not to let differences of opinion interfere with normal human goodwill.

Thanks GG for your good wishes.

7p is now my average

Today is my 88th birthday so I thought I should pen a few thoughts about IMM, trying to take a long view of this company.

My first purchase of its shares was made 11 years ago when I was 77. The price I paid then was 48.5p per share and little did I imagine that I was paying 22 times as much as I would be paying now.

So should I live for another 11 years and reach the age of 99, will the price have returned to the same level of when I was 77?

If it does, then I'll be somewhat the richer having used the ultra low price of the past two years to buy 22 times as many shares as I bought initially. Can one call that progress?

My fault is that I feel emotionally attached to IMM because of the hope it holds out as a cure for autoimmune diseases.

One of my sons has had his life blighted by Crohns Disease for 20 years. It's my enduring hope that the P140 platform will come up with a cure for this disease as well as for Asthma which afflicted him in his early years and the other diseases in this stable.

So I live in the expectation of a huge medical advance, not in the hope of making oodles of money.

Thanks, Wigwammer for your detailed and helpful response.

Wigwammer: On the 30th June you were advising me to be patient regarding the Lupuzor trial announcement.

I take comfort from the AGM report by wildbunch. He obviously got positive vibes from the IMM management team although he seems to be saying that they were non-committal about whether they would issue a RNS about the state of progress in arriving at patient testing.

He was confident enough with the news at the meeting and the attitudes of IMM staff to buy a further 200,000 shares. So let's wait and see whether we get an announcement of a CIDP trial with an up-front payment for IMM and a start date for patient trials in the new Lupuzor Phase 3 trial.

Wildbunch, thanks for your news and views of the AGM. Your purchase of shares this morning speaks louder than words.

Thanks wildbunch.

How do I give you my email address privately? Only Lisa within this community knows it as far as I know.