Member Info for Brand

https://www.google.com/amp/s/medicalxpress.com/news/2021-12-nose-cells-key-severe-covid-.amp

"However, once it was established, the interferon response began to hinder the replication of the virus. Consistent with this, when we added interferons before infection, we found that they potently blocked viral replication.

"This opens up the possibility that interferons, which are approved for treatment of other viral infections in patients, could be repurposed to develop interventions, such as a nasal spray, for preventing COVID-19 in certain clinical scenarios. These include helping to protect people who do not respond well to vaccines, or after specific high-risk exposures."

https://pubmed.ncbi.nlm.nih.gov/34875033/

'Our previous report showed that individuals with anti-IFN-?2 and/or IFN-? autoAbs constitute a
group at significant risk for developing critical COVID-19 disease [2]. Identifying these individuals
early in the course of disease for targeted intervention with compensatory therapeutics, such as
inhaled IFNb therapy, might alter their course of disease and improve outcome [7].'

He offered a lordship to Kate Bingham if she told him to who to call...

Boris currently on phone w RM offering bigger and bigger bungs to unblind P3 data to save his a**e ;-)

Sure is Oak. Same old tired lines. Same old tired accounts.

I'm blushing over here TL :)

Would just add that every lth here can be part of that roll out. Whether it's sharing info about SNG on social media, writing to their representatives or just letting your mates know down the pub.

Get that snowball rolling

A little reminder, just incase any of these clownshoes is asking why they haven't done delta yet.

We already know it works ;-)

https://www.biorxiv.org/content/10.1101/2021.11.16.468777v1

Hmmmm....

https://www.fiercepharma.com/pharma/astrazeneca-weighs-spinning-division-covid-19-vaccine-antibodies-into-separate-company

Spoiler Alert - We know it works ;-)

https://www.biorxiv.org/content/10.1101/2021.11.16.468777v1

'The Delta variant of SARS-CoV-2 maintains high sensitivity to interferons in human lung cells'

Direct link to the variant poster for anyone that wants to share with say, journalists, MPs, etc :)

https://c212.net/c/link/?t=0&l=en&o=3382352-1&h=2017075230&u=https%3A%2F%2Fwww.synairgen.com%2Fumbraco%2FSurface%2FDownload%2FGetFile%3Fcid%3Db13a246f-a9fc-4e7e-aac2-622208c3ac71&a=website

Expect they at least have to wait until the conference is finished.

XV,

The China market certainly is tempting, but I do genuinely believe the CCP will completely disregard any IP laws and reverse engineer SNG within days of approval. This doesn't concern me at all, but I think true authentic SNG001 will be the preserve of only the wealthiest in China who will insist on western pharma.

The good news is even 5% of the Chinese market would be absolutely massive.

This one out of China - they've dig a bit deeper and identifed which parts of the virus inhibit INF production

https://www.frontiersin.org/articles/10.3389/fcimb.2021.766922/full?utm_source=dlvr.it&utm_medium=twitter

'In summary, we identified SARS-CoV-2 proteins that antagonize IFN-I production and the IFN-I signaling pathway. The antagonistic steps of each identified protein were mapped onto different components of the IFN-I signaling cascade. Importantly, our study reveals for the first time that SARS-CoV-2 M protein inhibits IRF3 nuclear translocation by inhibiting the interaction between KPNA6 and IRF3, and S protein inhibits STAT1 activation and nuclear translocation by inhibiting the interaction of JAK1 and STAT1. This finding may provide promising targets for antiviral intervention. Our findings provide new evidence for the interaction between SARS-CoV-2 and mammalian host cells and contribute to a better understanding of the pathogenesis of COVID-19'

To my very uneducated eye it seemed to follow the same patter as previous polygon buys on Friday/today

Tbf city and sharedealer were both pretty much spot on.

NDN is in sng hq for the 'Virtual' conference smh.

TL

I think you've got it spot on with the warm up act. I don't know about stocks and shares (tho I'm certainly learning! :) But I do know about marketing

Sng will of course want to get the whole worlds attention when P3 data drops and while yes, 'weve got a cure for covid' will certainly turn lots of heads, you need to have all your ducks in a row, because if for some reason the message doesn't break though (say another huge news story on the day) you've shot your shot and are now a sitting duck.

By putting previous work in the frame, re-introducing SNG to those in the know, creating content of your most important aspects (posters, presentations = easily sharable content), building up your SM and company profile, you can build bigger circles of awareness and start to break through to the mainstream, priming the market for P3 release a few weeks down the road.

I would expect the PR/marketing team to have a day by day (if not hour by hour) plan for the next 4-6 weeks. (and I'm really looking forward to watching it come together)

Best

1m shares @ 2.05 = 2,050,000
1m shares @ 1.90 = 1,900,000

Gotta expect all that time and effort is well worth £150k no???

Fri morn sp was sitting at a nice 205, we got a barrage of de-ramping, negative sentiment and even a dodgy article to sew doubt. The trolls were even working overtime at the weekend. This morning, a barrage of small sells to bring the SP down and now there looks to be a large order being filled at 189/190.

Sound about right?

I don't know anything about this ESWI bar what I've seen on the website this morning - but just going by the sponsors alone, it would seem quite a good venue to be demonstrating your home run respiratory disease drug.