Member Info for Borsaci06

also not to be forgotten

EU criteria for an SME and GlioKIDS grant news

Preparations for a Phase II trial of safety and efficacy in 19 patients with Kinderspital, Zurich are well advanced.
The study endpoint is expected to be patient survival after 12 months

Nast
here you go:

https://uk.advfn.com/stock-market/london/midatech-pharma-MTPH/share-chat
https://twitter.com/search?q=%23mtph%20&src=typed_query&f=live
https://twitter.com/search?q=%24mtp&src=typed_query&f=live
https://twitter.com/search?q=%23mtph%20%24mtp&src=typed_query&f=live

spread what you like ( good / bad )

Seems like pretty bad news for the vaccine? Four strains already in one building?

"At least" four strains of COVID-19 found in Baltimore Ravens' facility
https://www.espn.com/nfl/story/_/id/30454991/at-least-four-strains-covid-19-found-baltimore-ravens-facility

Unlike flu, a deficient interferon innate immune response is associated with #COVID19 pneumonia, the lack of viral clearance, and subsequent cytokine storm
https://www.nature.com/articles/s41590-020-00840-x

This is for DIPG &
other rare, more likely to be fatal Childhood Cancers
https://twitter.com/HoCpetitions/status/1334196423156494340

lets see what this brings in next week

https://committees.parliament.uk/committee/326/petitions-committee/news/136874/mps-to-debate-a-petition-relating-to-research-into-childhood-cancers/

assuming trades are marked correctly
counted AT trades yesterday
BUY 144
SELL 104

trial in
Cardiff & Sweden

that said PATENT ( APPARATUS AND METHOD FOR MAKING SOLID BEADS )
adressed to:

(73)Proprietor: Midatech Pharma (Wales) Limited
Cardiff

https://twitter.com/robinmonotti/status/1334109385476497408
Robin Monotti Graziadei
@robinmonotti
The vaccine is NOT the end of the epidemic, the epidemic ended in June & SARSCoV2 is both seasonal & endemic. The vaccine is the beginning of the biometric vaccination passport linked to digital currency on the mobile phone as yet another tool of real time surveillance & control.
12:17 PM · Dec 2, 2020·Twitter for Android

https://twitter.com/flavinkins/status/1325923745215623169
Ersa Flavinkins
@flavinkins

Normally TMPRSS2 and ACE2 don’t coexpress, but with the mosaic pattern of the ACE2/TMPRSS2 cells, TMPRSS2 cells will fuse with ACE2 cells with the vaccine (mRNA). Forming syncytia is hich is both aneuploid and therefore likely cancerous, and also now coexpresses ACE2 and TMPRSS2

@flavinkins
Replying to
@NoWackyScience
and
@veryvirology
Expression of the S in any healthy, not-will-be-killed cells, are potentially carcinogenic by syncytial formation. Mitosis itself does not work properly with more than one nuclei in the same cell.

https://twitter.com/a_m_molenda/status/1325892608720297984
Aneta Molenda
@a_m_molenda
Replying to
@drakchaurasia

I don't like an idea of providing viral RNA sequence of spike to many people in the population (who have other accompanying viral infections). We may unexpectedly create next unknown virus by recombination of genetic material #COVID
https://www.sciencedirect.com/science/article/pii/S0092867420306309

https://twitter.com/BidoliNicola/status/1325900749574959104
Nicola Bidoli
@BidoliNicola
Replying to
@drakchaurasia

Dear @drakchaurasia
,R. Baric he also said in your interview
Down pointing backhand index

Rightwards arrow
..."The one more function we gave the virus is the
Right pointing backhand index
changed its antigenicity that is, any future vaccine, or antibody, would not have protected people from its infectious action". R.Baric.
https://www.huffingtonpost.it/amp/entry/e-possibile-creare-un-virus-in-laboratorio-senza-lasciare-traccia-la-risposta-dellesperto_it_5f5f3993c5b62874bc1f7339/?__twitter_impression=true

dr a k chaurasia
@drakchaurasia

dear Adam, what vector is being used in Pfizer vaccine?
even if this mRNA binds to TLR, is coV2 genome included in to replicate?

Adam Gaertner
@veryvirology
Replying to
@drakchaurasia
Lipid bilayer fusion. It's encased in a liposome. No, there's no replicating vRNA included. The danger is in whether the mRNA can be degraded or whether it's persistent. As far as I know their work is proprietary so there's no way to know, but I'd expect a vax to try to last.
https://twitter.com/drakchaurasia/status/1325857995834548224

Keep reading the thread

Adam Gaertner
@veryvirology
The Pfizer vaccine inserts viral spike protein mRNA into cells. If the mRNA is protected such that it is persistent, that spike will bind to TLR2 & TLR4, just like the virus, to cause the lasting inflammatory response we know better as CHRONIC COVID.

If it becomes mandatory, RUN

waiting more than 46minutes for what?

A1b2c3
SNG posters must have seen it by now

When add them together (Department of Health and Social Care + National Institute for Health Research)
are they planning to give sng001 a temporary authorisation for ..............................

Updated 16 October 2020
any product licensed by the European Medicines Agency before the end of 2020 will automatically be valid in the UK. Following the end of the transition period, the UK’s licensing authority will have new powers to approve medicines, including vaccines, itself.

In the UK, the HMRs contain several existing provisions relevant to the supply of medicinal products under pandemic conditions, regulation 174 being particularly relevant. Regulation 174 of the HMRs allows the licensing authority to permit a temporary authorisation for the supply of an unlicensed medicinal product for use in response to certain specific types of public health threat – the suspected or confirmed spread of pathogenic agents, toxins, chemical agents or nuclear radiation
https://www.gov.uk/government/consultations/distributing-vaccines-and-treatments-for-covid-19-and-flu/consultation-document-changes-to-human-medicine-regulations-to-support-the-rollout-of-covid-19-vaccines

Published: 19/11/2020
The trial is led by the Oxford BRC’s Professor Ling-Pei Ho, and locally by Professors Naj Rahman, the LCRN’s respiratory lead, and Duncan Richards. Eight patients took part in the national trial, at Oxford’s John Radcliffe Hospital.
https://local.nihr.ac.uk/news/inhaled-drug-for-covid-19-shows-positive-results/26232

Talk about vaccines:
This reminds me the licencee Emergex who raised $22m recently

Scientists develop a ‘nanoparticle’ COVID-19 vaccine that could trigger a 10-times stronger immune response than the reaction seen in survivors and protect against future mutated strains

Nanoparticles, whether they are natural or synthetic, mimic the structural features of viruses, which are often nano-sized themselves.

This makes it easier for the the nanoparticles to mold to the size and shape of the virus receptors.

UW Medicine’s vaccine candidate displays 60 copies of the coronavirus’s receptor-binding domain, which the virus allows it to dock to body receptors to gain entry into cells.
http://healthmedicinet.com/i2/covid-19-nanoparticle-vaccine-could-trigger-strong-immune-response/

No-one has ever produced a safe and effective vaccine against a coronavirus.
Birger Sørensen,
Angus Dalgleish &
Andres Susrud
What if, as I fear, there will never be a vaccine. I was involved in the early stages of identifying the HIV virus as the cause of Aids. I remember drugs companies back then saying there would be a vaccine within around 18 months. Some 37 years on, we are still waiting. Prof ANGUS DALGLEISH@MailOnline

10 Jul 2020 last update
This trial has been completed in UK (Global End Date: 30 Dec 2019),

End of Trial Status: Completed
Date of the global end of the trial: 2019-12-30

results should be very close

woul be lovely
if that buy is from Sabine Mueller, MD, PhD