RE: Exscientia24 Sep 2021 11:09
https://www.nanalyze.com/2021/09/ai-powered-drug-discovery-stocks/
Four AI Drug Discovery Stocks
Company Name Ticker Market Cap
(USD billions)
Exscientia TBD TBD
AbCellera ABCL 5.67
Schrodinger SDGR 4.42
Recursion Pharmaceuticals RXRX 4.52
Founded in 2012, Oxford’s own Exscientia raised $374.4 million in disclosed funding from a slew of investors including names like Softbank, BlackRock, Celgene, Bristol Myers Squibb, and Sir William of Gates. All that money was used to build an AI-powered design platform known as Centaur Chemist which combines the power of machine learning with the knowledge of human chemists to discover drugs faster. As seen below, Exscientia reduces the time it takes to go from target to candidate by 70%.
Once there’s a drug candidate, it then needs to proceed through the FDA drug approval process like any other. That’s an easy value proposition to understand, but the accompanying business model is anything but.
If a software-as-a–service (SaaS) business model is to be rewarded for consistency and predictability, then a business model with unpredictable revenue streams should be penalized. While Exscientia’s revenues may appear to be starting out stable, there’s loads of volatility bubbling under the surface. There are two revenue streams – service fees and licensing fees – from which there can be four types of payments; upfront payments, research funding, milestone payments, and opt-in payments. Each relationship Exscientia has comes with its own terms. From collaborations to joint ventures, the business model quickly becomes so complex that it’s hard to fathom how anyone can keep track of what’s going on. So far, most of their revenues are coming from their relationship with Celgene.
During the periods ending December 31, 2019 and 2020, 69% and 83% of our revenue, respectively, related to the recognition of the Celgene up-front payments in line with our progress towards delivering up to three clinical candidate compounds.
Credit: Exscientia S-1 Filing
Then there’s the $4.6 million in revenues recorded for the first half of 2021 which consisted of 13% share ownership in a Chinese firm called GT Apeiron Therapeutics. While it’s counted as revenue, it sits on the balance sheet as an asset, albeit one that’s not likely to be very liquid.
While Exscientia has originated “the first three AI-designed precision drug candidates to enter human clinical trials,” their business model is far too complex for our liking. Complex business models = uncertain cash flows = stock price volatility. The same can be said for our next company.