Member Info for bignose58

Pom My point exactly. They should have gone with the 20 dose canister and saved us the extra 3 year wait. it seems to me that they were not truthful regarding the discussions and agreements they had with the FDA, otherwise we would now be in a position to launch EU and USA together. As you note, they have definitely withheld some of the facts.

Pom, that would be so true..... So here is a little reminder of what we have let slip through our fingers for the last few years through inexperience. remember launch will be in beginning of 2020. Thats nearly 6 years from the below statement. Plethora (AIM: PLE) is pleased to inform shareholders that our recent meeting during Q1 2014 with the United States Food and Drug Administration ("FDA") has now unambiguously defined the path to a successful submission of the New Drug Application for PSD 502. Appropriate actions are well underway with the Company's various consultants. Importantly, the FDA has confirmed that premature ejaculation is an area of high medical need with a requirement for effective therapy and recognises the importance of the initiatives that Plethora has made towards this goal. Not wanting to dig up old ground, but for me this delay in FDA approval is unforgivable given what they alluded to in the above. I still cannot get my head round why they never went forward with the 20 dose canister in the beginning and possibly changed via a variation later, we would still be more advanced now even if they had, which we now know they won't.

Pom Thanks for the research, I looked through the old RNS�s, but obviously missed that part.

Although JM closed everything down to concentrate on Fortacin, surely the time is right for a resurrerection or a 2nd cumming....... sorry, I just couldn�t resist those two..... but still .... could this not be raised from the dead. Was Timms sold off........ I cannot find anything else on the matter.

Kicked into touch to concentrate on delaying Fortacine .... LOL I wonder what also happened to Timm Medical Technologies, Inc ..... wholly owned by PLE ?

Whatever happened to this ? I was going through some old PLE RNS's-I've posted below a couple of extracts: RNS Number : 1455I Plethora Solutions Holdings PLC 14 November 2008 Embargoed Release: 07:00hrs Friday 14 November 2008 Plethora Solutions Holdings plc New Study Confirms the Role of ErecAid� as First Line Treatment for Erectile Dysfunction Plethora Solutions Holdings PLC ("Plethora", AIM : PLE), the specialist developer of products for the treatment and management of urological disorders, announces results of a study confirming the role of its product, ErecAid�, as supplemental first line treatment for erectile dysfunction (ED). ErecAid� is marketed through Plethora's US subsidiary, Timm Medical Technologies, Inc. And RNS Number : 6773J Plethora Solutions Holdings PLC 08 December 2008 Embargoed Release: Monday 8 December 2008 Plethora Solutions Holdings plc ("Plethora" or "the Company") Clinical Update: Final analysis - PSD502 for Premature Ejaculation All Primary and Secondary Endpoints Met in Phase III Pivotal Trial Both Patient and Partner Satisfaction Increased Significantly 86% of Patients Rated the Treatment as Positive Well Tolerated and Devoid of Systemic Side Effects

Probably run out of the 12 dose can in English due to Recordati taking up all the current and future manufacturing runs for the EU launch and all that's available are the remaining 20 dose cans.

All very interesting although the last couple of words I found were the most. One of them reminded me of that old Paul Robeson song from the film showboat.... but this one had muppet frogs singing.. Ol' man "ribbit" that ol' man "ribbit"......... a bit more entertaining me thinks ..... lol

pxsmaaad, One other point which is probably the most important is that our product is far superior than any of the others with respect to onset time and side effects. This in itself will play a huge part in sufferers using it and for those who will definitely migrate from the other products. No one wants to wait several minutes let alone an hour or two a for a product to work, they will be embarrassed enough to begin with. To be able to pop to the loo apply the drug and carry on as if nothing happened has to be the biggest positive thing. Sufferers will feel so much more comfortable using it. When you compare the different ED drugs, they all basically work in the same way hence a large distribution of sales between the big 3. For us, however, I'm sure Forticin will eventually be the "big one". With respect to our possible ED spray. Imagine the rush to our product if we do manage to get it off the ground. The above still applies. People want products to act near immediately without thinking too much about it. I'm pretty sure the ED spray will eventually come since even just by crushing a blue pill n rubbing it on the end of the floppy bit its effects, I understand, are much much faster than taking any drug orally. (this was something Dr Mike mentioned last year when I met him). Having a product in liquid form will just make it quicker.

pxsmaaaad. This has been discussed on this board years ago, even before the unfortunate demise of the founder, so I only consider this as news for new investors and I am in no-way knocking your research since its all part of the course in making an investment. As Pom would write...good sniffing. :-) Given the number of men who may suffer from the condition, there is more than enough of a market for both our products and a few more, so I personally have little concern. Obviously I write this based on comparing sales of ED products which currently is all we have to go on. For me the product currently on sale in the States is just aiding us in market awareness. There are still many a man who would rather get the product through a doctor rather than going to a pharmacy and coming out will a pocket full of headache tablets .....LOL

Maybe you should have asked him to indicate if it was between 1 and 10 .... LOL As to your other query on ROW licenses. Are you expecting an update before the end of the year? Even though JG indicated that nothing would happen till after the EU launch ? Good if yes, but........?

Pom It was the same when I lived on the French Riviera. Wine could be bought in large plastic containers from the local supermarket. And as you write, similar to you, some of the cheaper red stuff tasted really good. I had about 300 bottles of nice wine n champagne which I had just bought before I decided to move to Australia. Took them all with me... was a bit expensive to to import them all but wtf. Australia only had their own expensive lesser quality liquid. Then I moved to Singapore and took the remainder with me there. Spent more money to import those bottles too. They ended up being probably the most expensive wine in the region ......lol. however, they still tasted the dogs **********. I still considered it was worth it. Now all that's run out, I only buy the cheap stuff which is ok as long as it has a high % of alcahol ....hic.

And remember there have also been many expected events that have been delayed. I personally think the market is still very cautious even with the 4mill since there is still nothing to stop a possible delay (due to the toilets being clogged or the ash trays not being emptied....or anything else...). We will only be informed closer to the event. I'm not suggesting there will be, but past experience will surely lead the market to be highly cautious. As such I see a healthy lift in SP once the EU launch news is out followed by the 2nd 4mill payment. Just my opinion for what its worth.

Pom you are lucky. My wife us Chinese, so a double whamy

To understand the wokings of the Asian mind would take many years, so ypu will never nose ;-)

So, given the increase in volume on the back of what I would consider as not much of an announcement, it would still indicate traders will be working this right up to the EU launch. I'm sure many probably didn't even read the announcement and just jumped in on the rise as usual. I would guess that most major long-term positions were all taken up last November and what we are seeing since are just day traders with maybe a handful of small new long-term investors who see the potential upside within the next 6 months (having read through all the announcements since last year). Just my take on things from watching how trading has been since last November. But what do I know ;-)

Very difficult to do when they themselves are in a deep sleep....;-)

Well..... That didn't last long. Looks like its currently being driven by traders and probably by the same ones who have been working it the last few years. If there is no more news to help sustain the SP, I can see it slowly drifting back down again which means an even lower springboard to bounce off from. i.e If the starting point is high, the SP will reach high highs on the EU launch news, otherwise it will only be low highs or even high lows.... ;-)

Probably aiming for the weirdos who like to have their wing dang doodle pierced. The idea of having ones pri%K, pricked was probably a turn on with added benifit of ED longevity.....LOL

Unfortunately not. I rarely email Jamie these days since whatever he seemed to respond with in the past has turned out to never been correct... :oD Although now everything has been sorted I may just ask him and he may feel a bit more willing to be truthful ....LOL At the moment, I just speculate like you that this must have something to do will eventual entry in to China