Member Info for bighammer

Just a thought, not accusing anyone but if this is correct then there should really be an after hours RNS to either confirm or deny, NHS and NICE were also running pilot testing for lab work. A big car crash with the sp with no conformation officially, is this on NICE website???

The problem is, all 3 added a little to the table but on their own none of them are right for a small company like this in the big meat market factory of Rand D.

Roger, or like our last CEO said , they are fed up with being mucked around and everything taking and age , this is the problem with texts e mails etc it can be read in a number of different ways, a good old fashioned chat gets the info/reply correct and straight away. Not as big a car crash as could have happened but at least we know roughly where we stand financially, did nt say it was a good position though.

£2-3m required i think some how , but no idea how.

Good news is they are going for both tests to FDA, bad news is not much cash left. Lets see what options are open to them and how much they will look to raise????

So they have been reccomending lab testing but the service has nt been available and they are testing to find somewhere it can be done , but they have a test ready to go , well done NICE lol.

Old but interesting,

What does this mean?

Currently, there isn’t an NHS lab-based service offering this genetic test in England. To

address this, NICE and NHS England are running a pilot project to test an early version

of the service. This pilot will take place at four sites in England, including Doncaster

and Bassetlaw Teaching Hospitals (DBTH). The project is led by Dr. Ahmad Maatouk,

Stroke Lead, with support from specialists at the National Stroke Programme, NHS

England Genomics Unit and NHS Network of Excellence in Pharmacogenomics.

The main objective of the project is to design and test the first versions of a new end

to-end genetic testing service in the NHS to guide clopidogrel use after ischaemic

stroke or TIA. This includes understanding and developing workflows, clinical and

operational practicalities, laboratory requirements, and patient experience to inform

the broader rollout across the NHS.

NICE has recommended offering genetic testing to people who have recently had an

ischaemic stroke or a mini-stroke (TIA). However, they suggest starting this testing in

stages, beginning with patients at higher risk of having another stroke, such as those

who have had more serious strokes. During the pilot, we’ll focus on high-risk patients,

including those who’ve had a TIA or a stroke with minimal disability. The first tests will

Ahmad Maatouk, Stroke Team, DBTH NHS FT

27th November 2024

Purely my opinion , but i would be surprised if we see any offer until we have full FDA approval and sales in the US. Big pharmas are big for a reason , they do not take chances. They would much rather pay hundreds of millions if not billions than buy a company for 50m quid and hope they can make sales. Most if not all takeovers are for profitable companies with no risk, but i agree within 2 years that is possible if we get FDA approval next year.

If it comes good then i will be prepared to wait to get out , 18months to 2 years would bre my guess for full value, but top slicing along the way

Roger, it is very obvious we will need to raise more funds but if the roll out is announced in the next month and it is positive we should have an idea on how much we will need, i am still surprised we have not had orders from outside the UK yet and that is the worrying part for me .

It would be good if the company gave an update on timelines regarding rollout , just confirming that August is the cut off time for comments and publication after that . Good work again Jimi, early mid September could well be a target for publication, the only question is will it be in time before we run out of money. we can only guess atm , September to November are the best guesses so i am hoping the BOD have this in hand with financial package or raises in the pipeline. as there has been no RNS as yet then even they dont know officially what is going on but hopefully they have been in constant contact throughout the proccess.

EC, lol. Pot and kettle.

Most of those handy appliances are useless, ended up throwing loads of them away lol.

Gloria, given that option would you not cough up the £100 straight away??. This is where NICE really need to look at the bigger picture, yes lab testing is cheaper on bulk testing, how much compensation would the NHS have to pay out if you waited for a lab result, how much quicker could a bed become available with a poc test . I may not be the brightest button but if someone can see that then why cant others in charge, this not me talking as a shareholder but someone with a little common sense .

Stocksaint, lab testing will be cheaper on block as that is why tests can take 2-3 weeks to get results as they wait for a certain number of samples before they run the tests, but while you are waiting for results that hospital bed is being occupied at what, £300 per day?. This is the problem with NICE in so much as they do not take into account additional on going costs/savings to the NHS when making their reccomendations, within their own crieria.

More of an Aldi man myself. I think the big problem it seems is convincing the establishment that this is the way forward, progress. Why when they admit that test per test it is cheaper and quicker than lab tests, just dont get it?????

625m shares in issue

FDA application expected by Christmas with approval following Christmas , De Novo route could be done in 6 months

fully funded by June next year

imo with rollout up and running and FDA by x mas 10p will be a good target to aim for.

Hi Stephen, when we get news of commisioning we will have a better idea of which route they will go down , was thinking of trying to trade the shares working on the theory they might go on a fund raise with a 25% discount, this may not happen and go down another route . off to lake Come next month for my 60th , hoping to slowly watch the sp grow while travelling across the lake on a daily check in , here s hoping.

That s great news Junior.

Hi Stephen, just adding 2and 2, as the trial was extended to May, then Gino said in June we could be self funding in 12 months time it is going to be a positive outcome, only time will tell just seems boxes are being ticked slowly. How s the holiday going?.

Great feedback Junior, thank you. So in laymans terms i can understand i am assuming that they dont have to inform us of individual sales and the company hopes /expects to be fully self funding in about 11 months time.

Assuming we have cash in the bank for the next 3 months or so then they are expecting sales in the near future as we will not go from 0-£6m in a couple of weeks . For me that means 2 things, 1, we may well not need as much extra cash as i first thought and 2, it gives us a lot better leverage to raise any capitol required as there are forward sales in the pipeline which should aleviate some worries shareholders may have, great work sir.