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This helps reinforce the dermal epidermal junction and skin barrier function enhancing the skin’s resistance to both physical and emotional stress.

How does Zenakine™ differentiate from other neuroactives on the market?

Zenakine™ is aligned with market demand in substantiated neurocosmetic benefits. Unlike other neuroactives, it is the first ingredient with clinical instrumental measures on sleep quality and duration benefits. Our clinical studies show that it increases sleep score by 11.3 % (p

Https://www.sofw.com/de/news/interviews/5242-unlock-and-reveal-the-power-of-skin-s-chronobiology-to-combat-cortisol-damage-with-zenakine-2

Unlock and Reveal the Power of Skin’s Chronobiology to Combat Cortisol Damage with Zenakine™

Interview with Hishda Mohamed, Senior Marketing Lead | Insights and Innovation, Croda Beauty Actives

What is chronobiology?

Every organ of our body has its own internal biological clock, synchronised by the centralclock in the brain. Chronobiology is the science that studies biological rhythms and howthey influence our body's functions, including skin functions.

Why is it important in skin care?

The human skin follows a 24-hour circadian rhythm that influences different functions such as cell proliferation, repair and defence, regulated by clock genes such as CLOCK, BMAL, PER and CRY. The expression of clock genes oscillates in a 24-hour cycle, peaking at different times of the day. For instance, PER1 and PER2 expressions peak in the morning when barrier function is increased allowing skin hydration and protection against external aggressors. CRY1 and CRY2 expressions, in contrary, peak at night when maximal cell repair mechanisms occur to ensure skin regeneration. It is then important to maintain this rhythmicity to promote skin health and longevity. However, lifestyle and life challenges can trigger the production of molecules such as cortisol that perturbates circadian rhythms, disrupting proper skin functions.

What is cortisol and how does it impact our skin and wellbeing?

Cortisol is a key messenger that helps regulate our body’s response to psychological and emotional challenges. It is beneficial for maintaining skin homeostasis during occasional stress. However, chronic stress leads to excessive cortisol accumulation that disrupts circadian rhythm, weakens the skin barrier, and reduces collagen production resulting in skin fatigue, dryness and premature ageing.

What is Zenakine™ and how does it counteract cortisol damage?

Zenakine™ is a cutting-edge neuroactive ingredient designed to counteract the effects of stress on the skin and overall wellbeing. It works in sync with the skin’s natural biological rhythms, enhancing melatonin production to help improve sleep quality, elevating positive emotions and stimulating skin regeneration. After 1 month of use, Zenakine™ restores skin firmness by 13.3 % (p

Both the US and Australia are working on Monday 5th May and their markets are open.

The half-year results published on 26th March stated:

Due to the highly confidential nature of its business and market, shareholders will only see the impact from the Croda partnership upon our financial results at full year end, and long term, we believe the potential enhanced commercial opportunities could be considerable.

The Board believes that its dual strategy will result in Group profitability in the medium term, and increased shareholder value in the medium to long term.

The full year trading update last year was on 29th July 2024.

Coincidentally Croda's half-year results are scheduled for 29th July 2025.

Looks like the wall of silence is likely to continue for another 13 weeks yet, happy days.

Made my first purchase in May 2020, not sure if that means I'm a LTH or not. However, I'm very happy with my investment throughout the 5 years and I currently sit on a nice paper profit. I have no intention of selling or buying any more. The big issue with SA is lack of communication, when he does communicate it is one step forward and two back. The IMC is orchestrated, the questions only receive a fleeting glance with between 5 and 10% only ever answered and the rest ignored even after the event.

Thankfully we have Elrico and Alex to thank for keeping us interested and positive about future outcomes.

GLA

6th May you mean.

Oh dear another comedian, no thanks Dire.

Oh dear Solley, sorry to hear that mate. Hope it's not permanent.

you don't make any sense dustbin, what do you mean archived or do you mean achieved?

many aim companies are absolute ****e, sbtx are not one of them. you don't want them to act like the others do you?

Fair enough Toyin, the outcome is the same though.

OldsCool, nobody asked you for your opinion. This is a chat board and I'll post as often as I like, if you don't want to read my updates then filter me.

SBTX isn't a bluechip company, it's a small fry AIM company with the potential for growth and requires the CEO to build momentum by being open and honest with its shareholders.

Cheers Solley, hope you're well. Yes, I got bored reading all of the Tom's garbage on here so didn't think it was worthwhile posting until something interesting materialised. I think things may be warming up here. Good luck, hope your golfing is going well.

Croda will be releasing their half-year results on 29th July 2025. They may give a trading update earlier, who knows. As Toyin has stated SA has delayed providing any meaningful data for a number of months. SA continues to kick the can down the road and has zero interest in communicating with his shareholders. Agreeing to do IMC 6 times a year for a CEO in charge of a growth company is absolutely pathetic IMHO.

I think you've covered the wording 'mainly lifted'. What isn't being lifted then?

Article today covering French company interest in ITV.

https://www.sharesmagazine.co.uk/article/itv-receives-takeover-interest-from-french-media-giant-banjay

None of us know when the NDA ends, you're just guessing and hoping.

SP started the month on 24.25p and ended on 23p, during which a blockbuster cosmetic ingredient with the catchy name Zenakine was launched. What happened? Well there was a standing ovation in Amsterdam on 8th April and then........nothing. Oh well, missed out on the opportunity to build any momentum with no media coverage, lost behind a wall of silence called the NDA. Let's hope May/June is more interesting.

GLA

13.3 close, took it down as per usual.

Manprit didn't have the choice.

He didn't say all of the NDA would be lifted (only a lot). He didn't say when (only either May or June). So what isn't he able to tell us? Might get some high level numbers if we are lucky. He signed the NDA and you would expect there to be a date of when it concludes rather than keeping everyone guessing. There always seems to be something missing with SA, which is very unusual in somebody so highly professional and with full integrity don't you think.