Member Info for 13thmonkey

phase 1 trials are about safety, it is perfectly normal, and expected, to have patients who are not reactive.

we need cash now. the dx business can now been seen as a cluster****, the previous management paid that price. we need the cash, and be seen to have the focus, more than the slight amount of profit.

these are 'limited results' from a phase 1 trial, not a phase 2 trial, not a phase 3 trial.

the end game is either a buyout in which case the further along the path of the trials we are, the better the price, or licensing win which the same is true, or going solo in which case we'll need to hit phase 3 at some point.

the sp is ****, but the potential is great.

Les is that a chatgpt summary? Do you have access to the original?

As far as I'm concerned she's gone back to the US on her usual cycle of working a bit in the UK and a bit in the US, I saw no mention of a non working period. I might have missed that tweet though.

So are we in a position that if there is a takeover in the woods and no one is around to hear it, does it make a sound?

You can do the transcript next time if you want.

Thanks thompi, I knew it wasn't going to soon.

Didn't CC literally say it would be a good while and a stage later before the US.

Touk you are making the claim that the rate is not good enough, so what is it? You make the claim your provide the evidence.

I weigh those 'facts' against the tumour shrinkage fact that we've been shown, and so what if the half life is short, it's doing it's job.

Could more frequent be better? 3w is based off what we do with dox, which needs a big gap to let the patient recover. If less/no recovery is needed then is 2w better than 3w? We need to know, BP needs to know, the FDA needs to know.

Half life improvement may be beneficial elsewhere.

Again the 2 week test will test both efficacy and toxicity so can the kidneys clear it.

Same facts, different implications.

Same touk.

They'll be one of many trying to the same thing, the last batch have had their ups and downs, mostly downs.

CJ back to an earlier point £5 is nothing to BP, if that offer came in, £6 would be right behind it from someone else.

As soon as a 50 plus 50p dream was even thought of someone else would outbid it because it's useful to many BPs. And so on until they start to think it's a bit pricey and then the outbidding will stop. We do not have just one potential buyer, there are more than a couple that would benefit both for themselves and to prevent a competitor from having the platform.

Livedataaccount, does it? what are they? I've not seen a new strategy every meeting.

Did you listen to the Wednesday interview?

Touk, regarding the below, I could have sworn that you had the persona of a naive investor who was hoping against hope that this would come off, as it was a decent portion of a pension pot or something. Rather than a 'better place to put the money right now' or is that a slip up?

Toukankahmoon

Posts: 1,759

Price: 53.00

No Opinion

RE: Going forwardToday 08:54

Agree with analysis but don’t see this as a buy quite yet because better place to put money for returns over next few months

Regarding Phase 3, there has to be a phase 3 either ongoing or planned at the point that phase 2 is used as registrational, so it should not add to the timeline, it can be in this case a post approval activity.

24 mins in: https://www.youtube.com/watch?v=eqj0hhgmX6U

And the whole purpose of this study is to find DLTs, note that not enough/not strong enough DLTs have been found to stop dosing faster or higher, as some of these were not in the final cohort.

Not being Juvenile Touk, just not mincing words, calling you out for what you are. I think you add little value from the posts i've seen, in fact you detract from it. So your opinion is irrelevant to me. PL75 adds value, so I speak differently to him, the message might not be what he wants to hear, but that's a different issue.

again touk, you prove my point. i've not once said search for it. and frankly i don't give two ****s what wyn says, he is solely here to be disruptive, why would anyone want him in a group, again it's not balance if the sole intent is to disrupt, which it is.

PL75, honestly, it's the responses here, and the last time, that make me (and it's not my decision by any means) not want to share them. But it doesn't actually matter, the purpose was to seed some questions that aren't 'how does it work', some interesting questions that haven't been approached before but should have been, the questions will be seen on the day, those that they are allowed to answer at least.

In fact if you all ask the same questions that probably tells Avacta more about what LTHs are looking for from them than if you self-censor and don't even ask the question because you know it's already been asked. Sure it'll cost them some time collating them, but knowing that there are say 10 wholly independent people all wanting to know the same thing is important in my opinion.

Meanwhile some can ask is it ribena coloured, and which flavour is it?