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ReNeuron Group begins dosing second cohort in hRPC study

Mon, 18th Mar 2019 11:33

(Sharecast News) - Cell-based therapeutics company ReNeuron Group updated the market on progress with the ongoing phase 1 and 2 clinical trial in the US of its 'hRPC' cell therapy candidate in the blindness-causing disease, retinitis pigmentosa (RP).The AIM-traded firm reported that, following a positive data safety monitoring board review of the clinical data from the first phase 2 patient cohort in the study, dosing of the second cohort of three phase 2 subjects had now begun, with the first subject in the cohort treated last week at Massachusetts Eye and Ear in Boston.It said the next dose cohort comprised patients who had a greater baseline level of visual acuity than those treated in the study thus far, providing a framework to better evaluate the safety of the treatment and to gain further clarity on the strong efficacy signal that was seen in the first phase 2 cohort.Last month, ReNeuron reported that all three of the first cohort of subjects in the phase 2 part of the study had reported a "rapid and significant" improvement in vision, on average equivalent to reading an additional three lines of five letters on the EDTRS eye chart - the standardised eye chart used in clinical trials to measure visual acuity.The company's RP clinical programme benefited from orphan drug designation in both Europe and the US, as well as 'fast track' designation from the FDA.As it had previously reported, the company expected to report further short term readouts in mid-2019 from the ongoing study."We remain extremely encouraged by the positive efficacy data we have seen thus far in the phase 1 and 2 study with our hRPC cell therapy candidate in RP patients," said ReNeuron Group chief executive officer Olav Hellebø."These results have already attracted considerable interest, particularly from those in the ophthalmology field, and we look forward to reporting further results from the study as it progresses over the coming months."As at 1135 GMT, shares in ReNeuron Group were up 6.41% at 74.49p.
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12 Sep 2018 14:44

ReNeuron pleased with progress on several therapy fronts

(Sharecast News) - Cell-based therapeutics developer ReNeuron Group updated the market on its trading on Wednesday, as investors gathered for the firm's annual general meeting, announcing that following recent co-ordinating ethics committee approval, the first clinical site has now been initiated in the US Phase IIb study with its CTX cell therapy candidate for stroke disability.

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12 Sep 2018 13:54

ReNeuron Expects To Enroll First Patient For Stroke Study Shortly

LONDON (Alliance News) - ReNeuron Group PLC said Wednesday it expects to enroll the first patient in its stroke disability study "shortly".The company said that the first clinical

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5 Jul 2018 16:01

UK Earnings, Trading Statements Calendar - Next 7 Days

Friday 6 July SVM UK Emerging FundFull Year Results Monday 9 July GroupHalf

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19 Apr 2018 13:17

ReNeuron Wins GBP1.5 Million Grant For Stem Cell Therapy Development

LONDON (Alliance News) - ReNeuron Group PLC on Thursday said it is the "lead" industry participant in a new GBP1.5 million grant from the UK's innovation agency Innovate grant has to

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3 Apr 2018 13:29

Portugal looks to renewables as March output tops mainland power demand

LISBON, April 3 (Reuters) - For the first time in at least four decades, Portugal's monthly renewable energy production in March exceeded power demand

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26 Mar 2018 15:53

ReNeuron Now Expects hRPC Stem Cell Trial Data In First Half Of 2019

LONDON (Alliance News) - ReNeuron Group PLC on Monday said it has decided to adjust the number of clinical sites for its CTX stem cell therapy candidate study, and now expects

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5 Dec 2016 11:06

ReNeuron's first half revenues supported by new drug developments

(ShareCast News) - ReNeuron, an AIM-listed UK based developer of cell-based therapeutics, saw first half revenues double due to a series of successful drug trials. Revenues were £22,000 for the six months ended 30 September 2016 up from £11,000 in the first half of 2015. During the period, the grou

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4 Dec 2016 14:45

Sunday share tips: ReNeuron, Clipper Logistics, RM Secured Direct Lending

(ShareCast News) - Shares of ReNeuron are for brave investors only, said the Sunday Times' Inside the City column. The stem cell pioneer is scheduled to publish the results of second-phase clinical trials of its potential stroke paralysis treatment alongside its interim results on Monday. ReNeuron's

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6 Sep 2016 11:38

ReNeuron reports positive progress in clinical trials

(ShareCast News) - UK-based developer of cell-based therapeutics ReNeuron Group provided a trading update ahead of its annual general meeting on Tuesday. The AIM-traded firm reported that all patients have been treated in the PISCES II Phase II clinical trial of its CTX cell therapy candidate for pa

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7 Jul 2016 09:37

ReNeuron Annual Loss Widens As Product Trials Ramp Up

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4 Jul 2016 15:16

UK Earnings, Trading Statements Calendar - Next 7 Days

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13 Jun 2016 07:58

ReNeuron Completes Phase II Stroke Therapy Trial Patient Recruitment

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9 Jun 2016 08:55

ReNeuron Selects Glioblastoma Multiforme As First Clinical Target

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8 Jun 2016 08:36

ReNeuron Progressing Blindness Candidate Through Phase I/II Trial

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15 Mar 2016 09:52

ReNeuron Says First Patient Treated For Retinitis Pigmentosa

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