Microscope maker Renishaw says cost cutting will offset the impact of tough market conditions and claims an operating loss for the second half is expected to be "somewhat less" than the £10m flagged in March. The company, which supplies microscopes, scanning probes and other devices, has already announced 500 redundancies and voluntary pay cuts.IT services company Computacenter is going well after it said it expects first half profit to be well ahead of the same period the previous year having seen strong trading in the first four months of 2009.On the downside, PV Crystalox Solar, which produces silicon wafers for use in solar power generation systems, falls after saying it expects first half revenues to take a 10% dive from last year's half-yearly revenues.Punters did well at the Cheltenham Festival in March, but that was bad news for bookmaker Ladbrokes which saw profits plunge 34% in the first four months of 2009. The shares are down 11%.FTSE 250 - RisersRenishaw (RSW) 407.75p +7.30%Computacenter (CCC) 179.00p +6.55%JPMorgan Indian Inv Trust (JII) 283.50p +5.78%Pace (PIC) 176.50p +5.37%Peter Hambro Mining (POG) 609.50p +5.18%Bellway (BWY) 680.50p +4.29%DSG International (DSGI) 38.00p +4.11%Croda International (CRDA) 558.50p +4.10%Inchcape (INCH) 19.25p +4.05%BlackRock World Mining Trust (BRWM) 373.00p +3.83%FTSE 250 - FallersPV Crystalox Solar (PVCS) 91.75p -15.05%Ladbrokes (LAD) 199.25p -11.35%Morgan Crucible (MGCR) 104.50p -10.11%GKN (GKN) 107.00p -9.13%Tullett Prebon (TLPR) 253.75p -8.72%SThree (STHR) 210.00p -8.50%Enterprise Inns (ETI) 131.00p -7.09%Hansard Global (HSD) 135.25p -6.72%Babcock International Group (BAB) 470.25p -6.14%Kier Group (KIE) 1,022.00p -5.37%