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Oh dear
The daily threads of the ultimate tangential summariser, supported by the conductor of the orchestra of gloom and doubt, who now proclaims the cold unit trolls are being cruelly treated.
What a sad place this board has become.
News is coming one way or another, but beware this board because it’s full of sharks and not all of them have obvious fins.
Sakura - you are a troll, plain and simple.
You have no interest or belief in Synairgen’s drug but still come here to “warn others” of “scientific misinformation” on a stock that is down 90% odd. You talk about mental health? Yes, coming here telling long suffering holders who are down heavily that Synairgen will likely be insolvent in a few years is very helpful.
You acknowledged that your views are unlikely to be well received. If you can’t handle the responses, clear off.
The accusations being put forward against contributors to a niche investor forum are pointless quibbles at best.
None of this dialogue will ever influence shareholders’ sentiment, so why bother to state it?
I read each contribution at face value initially. Should a series of comments from an individual strike me as being nonsense, then I have the option to filter the author. To date, very few contributors have fallen in that category since the migrations of less than helpful individuals to the advfn board some time ago.
The major issue regarding Synairgen, as I see it is the company’s perceived inaction over twenty six months. We have read about several successive incarnations of “forthcoming trials”, dialogues with significant partners, and appointments and departures of pointless major staff.
It is the company’s leadership that should be under major scrutiny. They are rewarding themselves with high salaries, and have produced nothing concrete, above speculation that is, to date in over two years.
Should we still be in the position where we are hoping for the best, but preparing for the worst regarding P2 trialling - due to having no idea whatsoever about the progress, if any, that has been achieved over the last seven months or so?
The company’s CEO has hardly raised his head above the parapet for more than two years! Is he still at the helm? If so it would be good to receive an update from him.
Rant over!
Should we receive promising news of the aforementioned P2 trials in the near future, I will be more than happy to apologise to this forum for sharing these grim thoughts. However, my view of the inappropriate way that Synairgen has disregarded its investors, LTIs in particular, will remain, whatever the future may bring.
GLALTIs.
Pandemic experts express concern over avian influenza spread to humans. Dr Jeremy Farrar, Chief Scientist at the WHO, said that the virus has an extremely high mortality rate among humans already infected with it. Underlines critical need for vaccines, therapeutics, diagnostics.
https://twitter.com/COVID19_disease/status/1786372468401451086
How has it been proven that I am a liar? I was at Cambridge dept of clinical medicine 86-87; Salisbury 87-89; ILRAD 89-92 (Nairobi); SKB/ GSK 93 - 99; Cambridge again 2000-2007…
What in your wildest imagination makes you assert this is not true. I use social media very little but hear on the radio that this sort of thing goes on and it impacts people’s mental health.Unpleasant people making unfounded allegations.
I make no complaint to those who think I am wrong but I find it unnecessarily unpleasant that people should hide behind a forum like this to insult and make false allegations
Medication time Fruits
You're making yourself look silly now Doc.Dan. You really want to trade what little credibility you have left defending the Walter Mitty characters on here...? Be my guest. Most investors aren't that stupid.
Sakura7 has been proven to be: (a) a liar about their professional experience and (b) correct about the outcome of P3.
For what it's worth, I suspect it is another damaged poster with access to a captive audience.
Also, the poster behind the Manifesto account is not a woman. No woman types "tee hee hee", etc.
It closely resembles Mrs Doubtfire and "Got to sign off now to get my fella's tea ready - he'll be in soon".
Fruits - it is outrageous libel to say I am lying about working with David Tyrrell. He was a wonderful and kind mentor . Why would you say such a thing?
Fair enough Jint - I wasn't defending S7's entire posting history particularly and might have referenced that thread maybe - but I was simply addressing the ludicrous idea proposed by Fruits that S7 is some kind of paid fifth columnist. Or that she appears just before positive news ( I mean - what positive news have we had ? ) Fruits has accused half of us as being agent provocateurs at one time or another and there's really only evidence of a few characters - the most prominent being Andybe4 - that fit this narrative.
God knows who or what Sakura 7 is.
Doc.D
Sukura7 stating that Synairgen had no patent for INF (which it hasn’t) and conveniently not mentioning the SNG001 formula that allows for nebulisation (patent granted), do you remember that series of posts?
Little wonder there’s a hostile response to their posts and motives.
We both know that's not true Doc.Dan, but carry on with this S'akura the 70's Scientist Fantasy', it's fun. You were obviously on one of your MIA stints when she was outed here as having lied about her time in Hampshire, you know, with Dr. Tyrell. It was proven to have been factually impossible, her dates on some matters being detached from reality by some 2 years or so. Now that is risable, for sure.
Https://journals.asm.org/doi/10.1128/jvi.01204-23
However, a trend in lower hospitalizations was observed in patients treated with SNG001 [86% relative risk reduction (P = 0.07)] (128). These three studies highlight the need for additional research into the effect of the route of administration/site of drug delivery not just for IFN-I but for all COVID-19 candidate therapeutics. In particular, given that SARS-CoV-2 is a respiratory virus, efforts should focus on evaluating nasal and oral inhalation routes to promote drug distribution to the respiratory mucosa.
As far as I recall Sakura7 has only posted once before significant news, and that was in late 2021 / early 2022. She was abused then as you are abusing her now. And then Sprinter dropped. We all hope she's wrong - and Synairgen has generated enough data to say that she is - but the idea that some malign force has 'wheeled her out' to generate negativity at sixpence is risible.
Can't think why anyone would want to put off new investors and eliminate any SP volatility right now. .... Oh, wait .......
Occupational hazard. Must be an RNS expected Monday - Sakura7 only gets wheeled out with the "I was a pretend scientist in the 70's" narrative when news drop looks close.
I'm gonna tell them to stop your cocoa if you keep nodding off Fruits.
Yawn.
Mr Costs
The positives are thin pickings but:
There will be another respiratory virus outbreak and governments and the private sector have that in their sights
Early intervention with IFN in an outbreak- say an old people’s home - could be useful.
If some efficacy can properly be demonstrated then this product might have a commercial future as an extra tool in the physicians tool box.
The share price is reasonably cheap
The final possibility is that the research on bio markers or the interaction with viruses and IFN suppression gives new insight as to how IFN may be used strategically . But that is speculative at the moment.
What seems really unlikely is that this will become the blockbuster some think it will.
I repeat people have been saying IFN will revolutionise therapy since the 1970s.
Given where we are and the cash spend I doubt the company will survive but it might
The spread here is fecking a joke for penny share
Hear hear DocD and T-P,
We all await illumination on the strategy by the company and I have zero to add, other than hoping that all us LTI’s will eventually get some meaningful results 🤪🤔🙏
MrCosts.
LTIs, like myself, are the wrong people to seek advice from. I have made the same error as yourself, in holding too much stock prior to the P3 trial outcome in Feb 2022. Further, in retrospect, I should have sold out and invested elsewhere when TFG Holdings added to their stake resulting in the only share price rise with an underlying cause in over two years.
Doc.Daneeka has provided a good summary of the last two years from an LTI's perspective. To summarise, after all this time, we are still waiting for a detailed announcement from Synairgen to launch their strategy. This needs to happen soon owing to the company's diminishing cash reserves. I am reading Spacman's contributions with interest. However, like all LTIs, my hopes are pinned on, hopefully, imminent news from the company concerning the P2 trials. For sure, they have not endeared themselves to LTIs by not issuing any updates for so long.
GLALTIs.
What company was that Aether?
Doc.Dan - Yes, that sums it up.
The company I was originally going to invest in subsequently increased four fold.
In normal circumstances, I don't think I would have invested in this company.