George Frangeskides, Chairman at ALBA, explains why the Pilbara Lithium option ‘was too good to miss’. Watch the video here.
London South East prides itself on its community spirit, and in order to keep the chat section problem free, we ask all members to follow these simple rules. In these rules, we refer to ourselves as "we", "us", "our". The user of the website is referred to as "you" and "your".
By posting on our share chat boards you are agreeing to the following:
The IP address of all posts is recorded to aid in enforcing these conditions. As a user you agree to any information you have entered being stored in a database. You agree that we have the right to remove, edit, move or close any topic or board at any time should we see fit. You agree that we have the right to remove any post without notice. You agree that we have the right to suspend your account without notice.
Please note some users may not behave properly and may post content that is misleading, untrue or offensive.
It is not possible for us to fully monitor all content all of the time but where we have actually received notice of any content that is potentially misleading, untrue, offensive, unlawful, infringes third party rights or is potentially in breach of these terms and conditions, then we will review such content, decide whether to remove it from this website and act accordingly.
Premium Members are members that have a premium subscription with London South East. You can subscribe here.
London South East does not endorse such members, and posts should not be construed as advice and represent the opinions of the authors, not those of London South East Ltd, or its affiliates.
W$,
Thanks for the good thought.
Don’t even try working this out but if ff is accepted as a drug then this could be a ready made market with the blessing of the Chinese government . “A study backed by scientists from the National Center for Cardiovascular Diseases in China which was updated in 2020 (www.ncbi.nlm.nih.gov/pmc/articles/PMC7008101/#) stated that:
· the prevalence of Cardiovascular Disease ('CVD') in China has been increasing continuously since 2006, with approximately 290 million patients in China who now have CVD; and
· two in five deaths in China are attributed to CVD, with CVD remaining the leading cause of death in 2016.”
Fully agree. Seems my mate and colleagues have timed there investment well
Great work Gixer. Seems lots of news in the pipeline
DP
if DSM had not loaded all the corporate overhead to keep the profit to PXS as small as possible, then the number of users, if 1p a shot came to us, is between 50 and 100,000. If 0.3 p a shot then scale up.
https://postimg.cc/5X4tjSqh
But DSM would have loaded the cost of Frederic, all the marketing, the Prof's business travel, the research costs, and patents. So to me, between 250 and 500K users is a good ballpark. Certainly not in the millions (imho)
Perhaps the Prof might tell us more in his next presentation ;-)
W-not sure-IF-will-be-too-happy-with-the-Prof-telling-commercial-secrets-$
If a pharma company is currently doing trials, then I would assume they have some kind of agreement with PXS, but we have not been told anything about that. Would be nice to know more about it.
I meant ‘it seems like a good pharma company Gix’
I would imagine that the whole pricing has changed or will soon. Some cost reduction will be passed on to customers.
Hi guys, great work as always, loads going on and only a matter of time now IMHO.
In reply to your future profit predictions.
My calcs:
Cost to produce 2p.
Wholesale price 11p
Profit 9p.
1 kg @ 6666 doses @ 9p would give a profit per kilo of £600.
Kilos per 1 million users requires : 1,000,0000/6666 = 150kg.
150kg x £600 = £90,000.
1 million users daily generates £90,000.
2 million - £180,000
3 million - £270,000
BUT, these are daily users, so on a yearly basis,
1 million - £90,000 x 365 = £32,000,000
2 million - £64,000,000
3 million - £96,000,000.
At the moment my subscription costs me £15 for 30 capsules = 50p each, so its quite feasible that a profit margin exists around the 6p- 9p area for each capsule and that is currently sold by Provexis.
Production costs will probably go even lower as will the retail price but a profit of 3 or 4 times production costs will still generate a very large income, I also expect it to go into may other products other than capsule form (yoghurts etc) with the drive for gut health, gut/brain/heart axis.
Its only when you start to look at the possible numbers it makes you realise the scale of its possibilities.
GLA
1,000,000 users
At a rate of 1kg/6666 doses, 1 million users would require
1 million users/
Hopefully get some news next week as DSM launch their new Health from the Gut solutions platform at Probiota tomorrow.
https://www.linkedin.com/feed/update/urn:li:activity:7026201548242194433/?updateEntityUrn=urn%3Ali%3Afs_updateV2%3A(urn%3Ali%3Aactivity%3A7026201548242194433%2CFEED_DETAIL%2CEMPTY%2CDEFAULT%2Cfalse)&fbclid=IwAR2LIJQUkaHXijDIyY65FZwsMPZMNHaUT96QJL0UDcsjuQrrV6aPoQSb0eM
and host a round table session on Tuesday.
Prebiotics
Towards the next generation
https://postimg.cc/B8mwJf7Q
Sounds like a pharma company Gix.
Wellsite,
Cost to produce
150 euro = £135
£135/kg divided by 6,666 doses in a kilo = £0.0201 or 2p a dose to produce.
Wholesale price in China
6000 RMB/ kg = £735
£735 divided by 6666 doses = £0.1102 or 11p a dose.
11p - 2p = 9p profit per dose.
Again these figures are taken from the published articles and maybe way off the mark (or my sums are wrong) but I recon your 2.5p profit/dose could be a little on the conservative side :)
W$,
So the main question is how many FF users have now and what is the annual growth projection?
gix
very nice find.
So the cost to produce is now 2.5p a dose ? I think it reasonable that gross profit should be greater than that to PXS.
Attached is a gross profit vs # users for 2.5p a shot profit
https://postimg.cc/PNz7CcYS
W;-)$
Surely must be further along the drug route than we are led to believe !
"the top local pharmaceutical company"
Could be Square Pharmaceuticals Ltd
"Square Pharmaceuticals Limited, the leading company of Square Group is the best pharmaceutical company in Bangladesh"
https://mybangla24.com/pharmaceutical-companies-bangladesh
"Square Pharmaceuticals Limited, the flagship company of Square Group, is holding the strong leadership position in the pharmaceutical industry of Bangladesh since 1985 and is now on its way to becoming a high performance global player."
https://www.squarepharma.com.bd/
“ Bangladesh, in 2009, it was discussed with the top local pharmaceutical company. It was closed due to Corona. Now the work has started again in full swing.'”
Can only assume it means 2019 not 2009.
A top local pharmaceutical company sounds good :)
Yes of course , hopefully it will become irrelevant when By health get approval and we start getting those multi million £ orders ,i wish
sphinx, the thing we don't know is how long it was taking DSM to sell 1 million Euros worth of Fruitflow.
Your calculation would suggest once a year but it could have been longer (or shorter).
"Stability and storage
Fruitflow® II SD is sensitive to air, heat and light. The product may be stored for at least 36
months from the date of manufacture in the unopened original container and at a
temperature below 25°C. The ‘best use before’ date is printed on the label. Keep container
tightly closed. Once opened, use contents quickly and store below 25°C."
http://technicaldocuments.dsm.com/product_finder/technical_documents/DNP/level10/DNP_DNPNA_000000000005015118_PDS_en.pdf
IF that’s the sort of money DSM we’re making from ff and giving us £300k ish then it’s just as well we walked away from the AA , that’s less than 10% to pxs when they knew we were struggling for cash ,makes you wonder about these huge companies ,they didnt get big by being generous with their cash .
That’s the kind of ballpark figure I have been assuming for the current total Fruitflow sales. That’s the current income and the prospective sales pipeline is substantial multiples of that.
Food for thought.
I cannot verify any of the following figures are accurate but they have been taken from published information.
Cost of Goods = 150 Euro a Kilo
https://kalbela-com.translate.goog/ajkerpatrika/lastpage/tuymwkotei?_x_tr_sl=auto&_x_tr_tl=en&_x_tr_hl=en&_x_tr_pto=wapp
Retail price in China 6000 RMB/kg = 818 Euro/kg
March 2021
https://mbd.baidu.com/newspage/data/landingsuper?baijiahao_id=1693898004131476920&id=1693898004131476920&wfr=spider&for=pc&third=baijiahao&c_source=kunlun&p_tk=9730STo9J072M1g0xXZRVfXfOzJJ9r8LvLuQGv4skK7MNiAqI8HYeB9K09cgtOn8fiMSVMUcB1umi2hwOL4dYQ2AIERpR0rat9oadroAjcCpXHq2bwDAtOwzJR9p22EoZ2di4FVXwXIzQKC7fm8PxL8YDg%3D%3D&p_timestamp=1675530080&p_sign=e431b0d5367a77fa702f49d6eee0bfe3&p_signature=026274465313f9b0ccec538b807c2596&__pc2ps_ab=9730STo9J072M1g0xXZRVfXfOzJJ9r8LvLuQGv4skK7MNiAqI8HYeB9K09cgtOn8fiMSVMUcB1umi2hwOL4dYQ2AIERpR0rat9oadroAjcCpXHq2bwDAtOwzJR9p22EoZ2di4FVXwXIzQKC7fm8PxL8YDg%3D%3D|1675530080|026274465313f9b0ccec538b807c2596|e431b0d5367a77fa702f49d6eee0bfe3
So if you take it that the stock DSM holds is worth 1 million Euro and we are buying it back at cost then.......
1 Million Euro divided by 150 euro/kg = 6,666Kg
6,666kg x 818 Euro = 5,452,788 Euro
Subtract 1 million Euro for cost of goods = 4,452,788 Euro profit.
Wouldn't that be good if correct????
Also says there has been 7 Chinese studies, cost of manufacture has come down massively ,Poland obviously feel it should be classed as a drug ! all looking good for pxs new production ability .
Some interesting points , seems a disproportionate number of countries selling ff and what pxs have received !
Some interesting comments/info from Asim in this interview for a Bangladeshi Newspaper.
Translation a bit iffy in places as well.
https://kalbela-com.translate.goog/ajkerpatrika/lastpage/tuymwkotei?_x_tr_sl=auto&_x_tr_tl=en&_x_tr_hl=en&_x_tr_pto=wapp