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Thanks Zen
I Wonder when Is the soonest we may hear how REMAP-CAP Trial Is doing.
Sax - how do you find the amount of patients currently dosed?
Best regards TA
Leiwounion thanks for your post.
To confirm how it’s administered in the REMAP-CAP trial
Interferon ß1a - 10 µg will be diluted in 1 mL of sterile water. The diluted IFN-ß1a will be administered as an intravenous bolus injection via a central or peripheral line. The injection will be followed with a 5 mL flush of sterile saline. IFN-ß1a will be administered once daily for 6 days or until ICU discharge, whichever occurs first.
Yes great to have a knowledgeable guy and a local in Finland who picks up on the subtle details .
95 new patients and counting with Covid-19 as of last night on REMAP .
Should be 200 + by end of next week I'm guessing , more if they have doubled hospital sites involved
Plus you have all top UK medical experts making plea for volunteers to take part in trials , although granted the Traumakine patients will be ones already in ICU or about to be , so not so much volunteering there .
I had a feeling that last week would be a watershed moment for Faron.
You couldn't really ask for more if you were trying to get your drug approved and marketed pronto.
Nominated for post of the year . Well done LeiwoUnion.
Nominated fornpistbof the year. Well done leiwoUnion.
Zengah I am not in medical department and didn’t understand that’s why I ask. U look very intelligent person so I know I will get answer.
There seem to be some confusion for some people about what medical trial at phase III actually means. A substance going to phase III has already been proven to work, small time, regarding the issue it's meant to affect. Traumakine has already went through a phase III trial, where the problem of ineffectiveness was raised; a result that was on the contrary to the phase II trial results. The result of ineffectiveness was put to question, as it was caused by interfering corticosteroids used during the trial III. I wouldn't question Traumakine's effectiveness in treating what is supposed to treat. What trial III's usually bring about, are the myriad possible side effects of the drugs, which may be found to be more severe than previously though (in shorter small time trials). I don't think this is an issue at all regarding Traumakine as interferon beta 1a has been studied and trialled through and through long ago.
To flip the question on its head - what happens if it is proven to be effective?
Obviously a massive demand short term for cv patients. And governments may want to stockpile to ensure supply in case of further outbreaks or a new strain.
But don't forget that ARDS was already a massive problem with an unmet need. Over 2 million people diagnosed every year. Mortality rates around 30-40%. Average hospital treatment cost of $50k per patient. 13% of survivors need permanent dialysis at a cost of $89k per year.
The need was there prior to CV and will continue King after. The remap-cap trial will rapidly accelerate that path to market and is funded by agencies.
Of course it might not work. But there's enough to this company aside from covid-19 that it could still have a very bright future even if traumakine is not successful.
Amazing 44% reduction and the trail has yet to begin.. this was on tolerability.
And to top this faron are dealing with puatents who have had 6 different treatments that have radiated the living daylights out of their immune system
Imagine putting someone on clevgen as the first treatment!
I guess this is why someone would invest here!
Gargar, you're not allowed to point out facts. Particularly the one about the 44% reduction in tumour size that happened to one lucky patient!
Obviously, as it's Friday night I/we will be accused of hitting the drink early!
Cheers all!
(Hic)
Zen stop filling this board with rubbish scientifically its not proven hence why they are at the trial stage .... don't give people false hope to part with the hard earned.
Its looking good but not proven Yet!
Yes Barry.
In the fairly unlikely event that is the case I guess we'll just have to make do with clevegen which has shown a 44% reduction in tumours after all other treatments failed. On a dosage finding study.
Oh and the secret weapon.
Funny but CEO has no doubts lol
If this is not work what will be happen than. I don’t think any one sure that this is going to work