Chris Heminway, Exec-Chair at Time To ACT, explains why now is the right time for the Group to IPO. Watch the video here.
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Chris, she was yeah. I wrote to her a few months back now, never heard back though. I asked her what she thought about SNG001, and whether she thought interferon in a nebuliser would be a better administration than subcutaneous injection. That’s been answered now though really :)
Yes, interesting to see EF supporting beta vs alpha. I wonder if she's wishing she'd joined Synairgen rather than BetterLife?!
Re ChinaTrial - And just to add it was used on medical workers .....
I think this is the trial in China that people are referring to. Interferon Alpha was used as opposed to our Beta and the application was by nasal drops so a completely different delivery method and for prophylactic (Preventative) use.
https://www.medrxiv.org/content/10.1101/2020.04.11.20061473v2
Miggy, I think Eleanor Fish was on a lot of those early Cuban/ Chinese studies? There was an article shared this morning where she was suggesting the use of Interferon Beta specifically (as opposed to alpha).
Woodstock, don’t mind a cash raise at all provided they do it at a higher SP. Certainly well over £2
Hewhodares, yea thats right! It was a lot of those early reports that encouraged me to invest so heavily. What we've seen over the last several weeks is the scientific validation of them.
And still no argument against it.
The Chinese interferon would have been Alpha. They had advisors from Cuba who discovered the drug quite some time ago. Their was indeed reports at the start of the outbreak that healthcare workers were using a spray in China. I actually did a lot of research into interferons, with others on here, pre manic Monday and I recall a medical trial report ex vivo that stated their was a virtual 100% success rate with stopping viral replication when healthy cells were given interferon and the virus was then applied later. It made me think at the time could this be a shield from the virus if given as a prophylactic. Would be a very interesting research project that.
There was a non-peer reviewed study released several months ago about a hospital in China giving their front line staff inhaled interferon (might have been alpha). None of them caught the virus.
This would obviously all have to be validated in clinical trials but the potential for SNG001 as a prophylactic is there.
Ducati2
Great post.....highlights SGN001 could have so much more potential.....thank you....
GLA
Her comment is on similar lines to an alternative vaccine option. Advantage being that it provides a naturally occurring protein that has been seen to be effective, and will be more so in the coming weeks with the French ATU. Licence deals will spring up all over the place and if Boris has stockpiled 4 months worth of PPE, imagine how much of this he'll stockpile (when he finally gets his finger out).
Woodie - wouldn't mind a cash raise when the business is already worth multiples of today's SP but we will have licensed or sold off part to a large pharma and they'll take care of the funding
The meat and potatoes of this company are outstanding however we must be prepared to be strong and ride the days of uncertainty and insecurity. We must remember this company this company has a coronavirus treatment that works.
My only reservation is we could be looking at a cash raise however the market cap of this company will reach billions imop. Dyor.
Was anybody aware of Chinese healthcare workers using inhaled interferon proactively? I would treat it with quite a bit of scepticism if it wasn't from "the Waldemar Von Zedtwitz Professor in the Department of Immunobiology and a Professor in the Department of Molecular, Cellular, and Developmental Biology at Yale University".
Her support for Interferon is positive enough without this fact, but this opens up a whole new use case which could be used in huge quantities if it had merit.
Wow
Wow
Wow
I was thinking the same thing when I was buying SNG share @ around 35-40p,
if it happen, it will be at least months away ,
this is one of my vision of this drug.
If this really happen the world will become normal,
and I will become a multi- millionaire. (Dreaming)
Wow. She really said this. This is mind blowing, no?
https://www.medscape.com/viewarticle/933621#vp_2
Medicine and the Machine from 8.22 mins
Topol: A paper just came out in Nature Reviews Immunology that reviewed four small ongoing trials and that multicenter study from China. All of them look quite promising. If you were to predict the future, do you envision that we all could have an inhaler with an IFN that we would take at first diagnosis or exposure? Do you think that's a possibility?
Iwasaki: As long as we can give the right dose without toxicity, that may be the future, especially in a preventive setting. For example, if your family member was diagnosed with a viral infection, you could potentially treat the rest of the family members with prophylactic IFN, and healthcare workers or people who are exposed to high-dose virus on a daily basis. That's what happened in China; they gave an inhaled IFN to healthcare workers and none of them were infected. So this may be a good thing to do in the future.